oxalic acid

Three steps

• glycyldehydrophenylalanineReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. transport of chloride and glycine (cytosol to extracellular)
  3. glycyldehydrophenylalanine + H2O = 2,3-didehydrophenylalanine + glycine

  Catalysed by SLC26A6, SLC6A9, SLC6A14, DPEP1extracellular space, cytosol

• 2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidineReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. Transport of L-Glutamine by Atb0 Transporter
  3. N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide + L-glutamine + ATP + H2O = 2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine + L-glutamate + ADP + phosphate + H(+)

  Catalysed by SLC26A6, SLC6A14, PFASextracellular space, cytosol

• kinetensinReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. Transport of L-Phenylalanine by Atb0 Transporter
  3. Chymase

  Catalysed by SLC26A6, SLC6A14, CMA1extracellular space, cytosolOne of 3 routes

• an N-(fatty acyl)-glycineReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. transport of chloride and glycine (cytosol to extracellular)
  3. a fatty acyl-CoA + glycine = an N-(fatty acyl)-glycine + CoA + H(+)

  Catalysed by SLC26A6, SLC6A9, SLC6A14, GLYATL2extracellular space, cytosol

• N-(9Z,12Z-octadecadienoyl)-glycineReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. transport of chloride and glycine (cytosol to extracellular)
  3. (9Z,12Z)-octadecadienoyl-CoA + glycine = N-(9Z,12Z-octadecadienoyl)-glycine + CoA + H(+)

  Catalysed by SLC26A6, SLC6A9, SLC6A14, GLYATL2extracellular space, cytosol

• acetaldehydeReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. Transport of L-Threonine by Atb0 Transporter
  3. L-threonine acetaldehyde-lyase (glycine-forming)

  Catalysed by SLC26A6, SLC6A14extracellular space, cytosol

• acetylcholineReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. transport of chloride and choline (cytosol to extracellular)
  3. Acetyl-CoA:choline O-acetyltransferase

  Catalysed by SLC26A6, SLC5A7, CHATextracellular space, cytosolOne of 3 routes

• pyruvateReach from here →
  1. Mitochondrial Carrier (Mc) Tcdb:2.A.29.7.2
  2. Citrate Transport, Mitochondrial
  3. (S)-malate:NAD+ oxidoreductase (decarboxylating)

  Catalysed by SLC25A1, ME2, ME3mitochondrial matrix, cytosolOne of 37 routes

• all-trans-retinoic acidReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. transport of chloride and formate (cytosol to extracellular)
  3. transport of formate and retinoate (cytosol to extracellular)

  Catalysed by SLC26A6, SLC26A4, SLC16A4, SLC16A5extracellular space, cytosolOne of 2 routes

• 4a-hydroxytetrahydrobiopterinReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. Transport of L-Phenylalanine by Atb0 Transporter
  3. L-phenylalanine,tetrahydrobiopterin:oxygen oxidoreductase(4-hydroxylating)

  Catalysed by SLC26A6, SLC6A14, PAHextracellular space, cytosolOne of 3 routes

• CHEBI:15477Reach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. 2-Methylbutyrylglycine Transport, Extracellular
  3. glycine N-acyltransferase (2-methylbutyryl-CoA)

  Catalysed by SLC26A6, SLC6A5, GLYAT, GLYATL2 and 1 moreextracellular space, cytosol, mitochondrial matrix

• propionyl-CoAReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. Carnitine Transport by Atb0
  3. Active Transport

  Catalysed by SLC26A6, SLC6A14extracellular space, cytosol, mitochondrial matrixOne of 2 routes

• CHEBI:15570Reach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. transport of chloride and glycine (cytosol to extracellular)
  3. transport of D-alanine and glycine (cytosol to extracellular)

  Catalysed by SLC26A6, SLC6A9, SLC6A14, SLC3A2 and 1 moreextracellular space, cytosolOne of 5 routes

• CHEBI:15611Reach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. transport of chloride and glycine (cytosol to extracellular)
  3. S-Adenosyl-L-methionine:glycine N-methyltransferase

  Catalysed by SLC26A6, SLC6A9, SLC6A14, GNMTextracellular space, cytosol

• 10-formyltetrahydrofolic acidReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. transport of chloride and formate (cytosol to extracellular)
  3. Formate:tetrahydrofolate ligase (ADP-forming)

  Catalysed by SLC26A6, SLC26A4, MTHFD1extracellular space, cytosolOne of 2 routes

• (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterinReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. Transport of L-Phenylalanine by Atb0 Transporter
  3. (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-phenylalanine + O2 = (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin + L-tyrosine

  Catalysed by SLC26A6, SLC6A14, PAHextracellular space, cytosolOne of 2 routes

• CHEBI:15699Reach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. transport of chloride and glycine (cytosol to extracellular)
  3. transport of glycine and homoserine (cytosol to extracellular)

  Catalysed by SLC26A6, SLC6A9, SLC6A14, SLC7A5extracellular space, cytosolOne of 52 routes

• betaine aldehydeReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. transport of chloride and choline (cytosol to extracellular)
  3. choline dehydrogenase (choline)

  Catalysed by SLC26A6, SLC5A7, CHDHextracellular space, cytosolOne of 3 routes

• trimethylenediamineReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. transport of chloride and lysine (cytosol to extracellular)
  3. deoxyhypusine synthase (1,3-diaminopropane)

  Catalysed by SLC26A6, SLC6A14, DHPSextracellular space, cytosol

• CHEBI:15727Reach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. transport of chloride and histidine (cytosol to extracellular)
  3. L-histidine:beta-alanine ligase (ADP-forming)

  Catalysed by SLC26A6, SLC6A14, CARNS1extracellular space, cytosolOne of 2 routes

• formateReach from here →
  1. transport of oxalate and sulfate (cytosol to extracellular)
  2. oxalate(in) + sulfate(out) = oxalate(out) + sulfate(in)
  3. oxalate(in) + formate(out) = oxalate(out) + formate(in)

  Catalysed by SLC26A6, SLC25A14, SLC26A2, SLC25A30 and 1 moreextracellular space, cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

• hexadecanoic acidReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. Carnitine Transport by Atb0
  3. Utilized Transport

  Catalysed by SLC26A6, SLC6A14extracellular space, cytosol, endoplasmic reticulumOne of 2 routes

• nicotinic acid D-ribonucleotideReach from here →
  1. transport of oxalate and sulfate (cytosol to extracellular)
  2. Transport of Quinolinic Acid
  3. Nicotinate-nucleotide:pyrophosphate phosphoribosyltransferase (carboxylating)

  Catalysed by SLC26A6, SLC22A6, QPRTextracellular space, cytosol

• CHEBI:15765Reach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. Transport of L-Tyrosine by Atb0 Transporter
  3. L-Tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)

  Catalysed by SLC26A6, SLC6A14, THextracellular space, cytosolOne of 5 routes

• N-carbamoyl-L-aspartic acidReach from here →
  1. transport of oxalate and sulfate (cytosol to extracellular)
  2. L-aspartate(in) + sulfate(out) = L-aspartate(out) + sulfate(in)
  3. carbamoyl-phosphate:L-aspartate carbamoyltransferase

  Catalysed by SLC26A6, SLC25A14, SLC25A30, CADextracellular space, cytosol, inner side of the membrane, outer side of the membrane

• alpha-D-glucosamine 6-phosphateReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. Transport of L-Glutamine by Atb0 Transporter
  3. L-glutamine:D-fructose-6-phosphate isomerase (deaminating)

  Catalysed by SLC26A6, SLC6A14, GFPT2, GFPT1extracellular space, cytosol

• androsteroneReach from here →
  1. transport of oxalate and sulfate (cytosol to extracellular)
  2. steroid sulfatase (androsterone sulfate)
  3. steroid sulfatase (androsterone sulfate)

  Catalysed by SLC26A6, STSextracellular space, cytosolOne of 3 routes

• ureaReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. transport of arginine and chloride (cytosol to extracellular)
  3. L-Arginine amidinohydrolase

  Catalysed by SLC26A6, SLC6A14, ARG1extracellular space, cytosolOne of 3 routes

• succinic semialdehydeReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. transport of 4-aminobutyrate and chloride (cytosol to extracellular)
  3. 4-aminobutanoate:2-oxoglutarate aminotransferase

  Catalysed by SLC26A6, SLC6A12, ABATextracellular space, cytosol, mitochondrial matrix

• L-cystineReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. transport of alanine and chloride (cytosol to extracellular)
  3. Transport of L-Cystine (L-Alanine antiport) by B0, +At Transporter

  Catalysed by SLC26A6, SLC6A14, SLC7A9, SLC3A1extracellular space, cytosolOne of 9 routes

• CHEBI:16284Reach from here →
  1. Mitochondrial Carrier (Mc) Tcdb:2.A.29.7.2
  2. transport of citrate and PEP (cytosol to mitochondria)
  3. dATP:pyruvate 2-O-phosphotransferase

  Catalysed by SLC25A1, PKM, PKLRmitochondrial matrix, cytosol

• (R)-3-aminoisobutyric acidReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. transport of alanine and chloride (cytosol to extracellular)
  3. (R)-3-Amino-2-methylpropanoate:pyruvate aminotransferase

  Catalysed by SLC26A6, SLC6A14, AGXT2extracellular space, cytosol, mitochondrial matrix

• 17beta-hydroxy-5alpha-androstan-3-oneReach from here →
  1. transport of oxalate and sulfate (cytosol to extracellular)
  2. steroid sulfatase (5-alpha-dihydrotestosterone)
  3. steroid sulfatase (5-alpha-dihydrotestosterone)

  Catalysed by SLC26A6, STSextracellular space, cytosolOne of 3 routes

• (R)-carnitineReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. transport of betaine and chloride (cytosol to extracellular)
  3. glycine betaine(out) + (R)-carnitine(in) = glycine betaine(in) + (R)-carnitine(out)

  Catalysed by SLC26A6, SLC6A12, SLC22A5extracellular space, cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

• L-citrullineReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. transport of chloride and glycine (cytosol to extracellular)
  3. transport of citrulline and glycine (cytosol to extracellular)

  Catalysed by SLC26A6, SLC6A9, SLC6A14, SLC7A9 and 2 moreextracellular space, cytosolOne of 39 routes

• ubiquinonesReach from here →
  1. transport of oxalate and sulfate (cytosol to extracellular)
  2. transport of fumarate and sulfate (cytosol to mitochondria)
  3. succinate:quinone oxidoreductase

  Catalysed by SLC26A6, SLC25A10, SDHD, SDHB and 2 moreextracellular space, cytosol, mitochondrial matrix

• nitric oxideReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. transport of arginine and chloride (cytosol to extracellular)
  3. L-Arginine, NADPH:Oxygen Oxidoreductase (Nitric-Oxide-Forming)

  Catalysed by SLC26A6, SLC6A14, NOS3, NOS1 and 1 moreextracellular space, cytosolOne of 2 routes

• CHEBI:16497Reach from here →
  1. Mitochondrial Carrier (Mc) Tcdb:2.A.29.7.2
  2. transport of citrate and PEP (cytosol to mitochondria)
  3. dGTP:pyruvate 2-O-phosphotransferase

  Catalysed by SLC25A1, PKM, PKLRmitochondrial matrix, cytosol

• CHEBI:16523Reach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. transport of chloride and glycine (cytosol to extracellular)
  3. transport of D-serine and glycine (cytosol to extracellular)

  Catalysed by SLC26A6, SLC6A9, SLC6A14, SLC3A2 and 1 moreextracellular space, cytosolOne of 4 routes

• protein polypeptide chainReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. transport of chloride and glycine (cytosol to extracellular)
  3. PROTEIN_BS

  Catalysed by SLC26A6, SLC6A9, SLC6A14extracellular space, cytosolOne of 18 routes

• 2-phenylacetamideReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. Transport of L-Phenylalanine by Atb0 Transporter
  3. L-phenylalanine:oxygen 2-oxidoreductase (decarboxylating)

  Catalysed by SLC26A6, SLC6A14, EPXextracellular space, cytosol

• pregnenoloneReach from here →
  1. transport of oxalate and sulfate (cytosol to extracellular)
  2. Steryl-Sulfatase
  3. Pregnenolone-sulfate sulfohydrolase

  Catalysed by SLC26A6, STSextracellular space, cytosol, Golgi apparatusOne of 4 routes

• CHEBI:16633Reach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. transport of alanine and chloride (cytosol to extracellular)
  3. L-selenocysteine selenide-lyase (L-alanine-forming)

  Catalysed by SLC26A6, SLC6A14, SCLYextracellular space, cytosol

• Met-tRNA(Met)Reach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. transport of chloride and methionine (cytosol to extracellular)
  3. L-Methionine:tRNAMet ligase (AMP-forming)

  Catalysed by SLC26A6, SLC6A14, MARS1extracellular space, cytosol

• 4-methylsulfanyl-2-oxobutanoateReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. transport of chloride and methionine (cytosol to extracellular)
  3. glyoxylate + L-methionine = 4-methylsulfanyl-2-oxobutanoate + glycine

  Catalysed by SLC26A6, SLC6A14, AADATextracellular space, cytosol

• N-[(S)-lactoyl]-L-phenylalanineReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. Transport of L-Phenylalanine by Atb0 Transporter
  3. (S)-lactate + L-phenylalanine = N-[(S)-lactoyl]-L-phenylalanine + H2O

  Catalysed by SLC26A6, SLC6A14, CNDP2extracellular space, cytosol

• 2-oxobutanoateReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. Transport of L-Threonine by Atb0 Transporter
  3. L-threonine ammonia-lyase (2-oxobutanoate-forming)

  Catalysed by SLC26A6, SLC6A14, SDS, SDSLextracellular space, cytosol

• tryptamineReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. Transport of L-Tryptophan by Atb0 Transporter
  3. L-tryptophan decarboxy-lyase

  Catalysed by SLC26A6, SLC6A14, DDCextracellular space, cytosol

• 2-oxoglutaramateReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. Transport of L-Glutamine by Atb0 Transporter
  3. L-Glutamine:pyruvate aminotransferase

  Catalysed by SLC26A6, SLC6A14, KYAT1extracellular space, cytosolOne of 3 routes

• 3-fumarylpyruvateReach from here →
  1. transport of oxalate and sulfate (cytosol to extracellular)
  2. transport of fumarate and sulfate (cytosol to mitochondria)
  3. 3-fumarylpyruvate + H2O = fumarate + pyruvate + H(+)

  Catalysed by SLC26A6, SLC25A10, FAHD1extracellular space, cytosol, mitochondrial matrix