17beta-hydroxy-5alpha-androstan-3-one

1. glucuronosyltransferase (5-alpha-dihydrotestosterone)

Catalysed by UGT2B4, UGT1A1, UGT2B28, UGT1A10 and 1 moreendoplasmic reticulumOne of 2 routes

1. steroid sulfatase (5-alpha-dihydrotestosterone)

Catalysed by STScytosolOne of 4 routes

1. 17beta-hydroxy-5alpha-androstan-3-one + NAD(+) = 5alpha-androstan-3,17-dione + NADH + H(+)

Catalysed by HSD17B2, HSD17B8, HSD17B10, DHRS9

1. 3beta-hydroxy-Delta(5)-steroid dehydrogenase (5-alpha-dihydrotestosterone)

Catalysed by HSD3B1, HSD3B2cytosolOne of 3 routes

1. 3beta-Hydroxysteroid:NADP+ oxidoreductase

Catalysed by AKR1C4cytosolOne of 3 routes

1. glucuronosyltransferase (5-alpha-dihydrotestosterone)
2. 5alpha-dihydrotestosterone 17-O-(beta-D-glucuronate) + UDP-alpha-D-glucuronate = 5alpha-dihydrotestosterone 17-O-[beta-D-glucuronosyl-(1->2)-glucuronate] + UDP + H(+)

Catalysed by UGT2B4, UGT1A1, UGT2B28, UGT1A10 and 1 moreendoplasmic reticulum

1. 3beta-hydroxy-Delta(5)-steroid dehydrogenase (5-alpha-dihydrotestosterone)
2. androst-5-en-3beta,17beta-diol + NAD(+) = 17beta-hydroxy-androst-5-en-3-one + NADH + H(+)

Catalysed by HSD3B1

1. steroid sulfatase (5-alpha-dihydrotestosterone)
2. steroid sulfatase (5-alpha-dihydrotestosterone)
3. Steryl-Sulfatase

Catalysed by STScytosol, Golgi apparatusOne of 2 routes

1. 3beta-Hydroxysteroid:NADP+ oxidoreductase
2. 5alpha-androstane-3alpha,17beta-diol + NAD(+) = androsterone + NADH + H(+)
3. steroid sulfatase (androsterone sulfate)

Catalysed by AKR1C4, AKR1C3, and 1 more