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Proteins/UNIPROT:Q96GA7
Catalyzes the pyridoxal-phosphate-dependent dehydrative deamination of L-threonine and L-serine to ammonia and alpha-ketobutyrate and pyruvate, respectively. Also exhibits racemase activity towards L-glutamate and D-glutamate (By similarity)..
Function from UniProtKB (Q96GA7), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
16 statements
16 statements · 7 reference databases · Subject: SDSL · Sources: Bgee, Hetionet, Human-GEM, Reactome, Rhea, UniProt, WikiPathways
7 reactions
L-seryl residueproton+ammonium+pyruvate
Catalysed by SDS or SDSL or SRR
Reaction pageLeft to rightBalancedEC 4.3.1.17, 4.3.1.19cytosol
Human-GEM MAR03883CC BY 4.0Reference data
2-aminoacrylic acid+waterproton+ammonium+pyruvate
Catalysed by SDS
10 names
Resolves to: SDSL
Reaction pageLeft to rightBalancedEC 4.3.1.17, 4.3.1.19cytosol
Human-GEM MAR03974CC BY 4.0Reference data
L-seryl residue2-aminoacrylic acid+water
Catalysed by SDS or SDSL or SRR
Reaction pageLeft to rightBalancedEC 4.3.1.17, 4.3.1.19cytosol
Human-GEM MAR04200CC BY 4.0Reference data
CHEBI:168572-oxobutanoate+proton+ammonium
Reaction pageLeft to rightBalancedEC 4.3.1.19cytosol
Human-GEM MAR04348CC BY 4.0Reference data
L-glutamate(1-)CHEBI:29986
Catalysed by SDSL
Reaction pageReversibleBalanced
Rhea RHEA:12813CC BY 4.0Reference data
L-seryl residuepyruvate+ammonium
Catalysed by SDS or SDSL or SRR
Reaction pageDirection not assertedBalanced
Rhea RHEA:19169CC BY 4.0Reference data
L-threonine2-oxobutanoate+ammonium
Reaction pageDirection not assertedBalanced
Rhea RHEA:22108CC BY 4.0Reference data