Catalyst TwinIn development

A human body you can run.

A simulator of human physiology, built the way chemical plants are designed: substances as components, organs as unit operations, and every rate a property you can trace to the sentence in the paper it came from.

Engineers design a refinery in a simulator before a pipe is laid. Biology has simulators too. What it has not had is one that shows where every number came from, and how strong the evidence behind it is.

LiveThe evidence graph underneath: every finding quoted from its paper, its evidence strength computed and never typed in.
In developmentThe desktop twin: a live flowsheet you rearrange, edit and run. Caffeine first, checked against human studies it was not built from.
PlannedModels assembled from the literature automatically, each parameter weighted by its evidence. Virtual trials, labelled as simulations.
AspirationalThe whole body as one simulation: every organ, every pathway, every substance.

Hear when it opens

Kept for twelve months at most, then deleted. Privacy

Running a lab or a company? Write to us about early access. The evidence it stands on is open to read now.

caffeine-oral · flowsheetIllustration · not a prediction

Every number has an address

Clearance, CL/F 1.6 mL/min/kg

CL/F (1.6 versus 1.0 mL/min/kg, p = 0.015) PMID 27100333

An illustration of the workspace: caffeine, 200 mg by mouth in a 70 kg adult, in a one-compartment model using numbers from the papers quoted above. It is not the twin’s validated model and not a prediction.

Weak evidence cannot render as strong
A prediction is never evidence
Every model ships with its misses