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Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Pathways

Names from Reactome and WikiPathways

pathways in the graph: 3,812

Filter pathways by name

#a b c d e f g h i j k l m n o p q r s t u v w x y z

1–100 of 3,812, alphabetically

10q11 21q11 23 copy number variation syndromeWikiPathways5352
10q22q23 copy number variationWikiPathways5402
11p11 2 copy number variation syndrome WikiPathways5348
13q12 12 copy number variationWikiPathways5406
13q12 or CRYL1 copy number variation WikiPathways5405
15q11 2 copy number variation syndrome

More of the reference layer

Biological processes
Anatomy
Cell types
Organisms
Materials
Regulatory assessments
Diseases

Evidence: Compounds · Outcomes · Papers · Search

WikiPathways4940

15q11q13 copy number variationWikiPathways5407

15q13 3 copy number variation syndromeWikiPathways4942

15q25 copy number variationWikiPathways5408

16p11 2 distal deletion syndromeWikiPathways4950

16p11 2 proximal deletion syndromeWikiPathways4949

16p12 2 copy number variation syndrome 520kb WikiPathways5510

16p13 11 copy number variation syndrome WikiPathways5502

17p13 3 YWHAE copy number variationWikiPathways5376

17q12 copy number variation syndromeWikiPathways5287

1p36 copy number variation syndromeWikiPathways5345

1q21 1 copy number variation syndromeWikiPathways4905

2-LTR circle formationReactomeR-HSA-164843

22q11 2 copy number variation syndromeWikiPathways4657

22q11 2 distal CNVWikiPathways5546

2q11 2 copy number variation syndromeWikiPathways5221

2q13 copy number variation syndromeWikiPathways5222

2q21 1 copy number variation syndromeWikiPathways5223

2q37 copy number variation syndromeWikiPathways5224

3-hydroxyisobutyryl-CoA hydrolase deficiencyReactomeR-HSA-9916722

3-Methylcrotonyl-CoA carboxylase deficiencyReactomeR-HSA-9909438

3-methylglutaconic aciduriaReactomeR-HSA-9914274

3q29 copy number variation syndromeWikiPathways4906

4 hydroxytamoxifen dexamethasone and retinoic acids regulation of p27 expressionWikiPathways3879

4p16 3 copy number variationWikiPathways5365

5-Phosphoribose 1-diphosphate biosynthesisReactomeR-HSA-73843

5q35 copy number variationWikiPathways5380

6q16 copy number variationWikiPathways5400

7 oxo C and 7 beta HC pathwaysWikiPathways5064

7q11 23 copy number variation syndromeWikiPathways4932

7q11 23 distal copy number variationWikiPathways5401

8p23 1 copy number variation syndromeWikiPathways5346

8q11 23 RB1CC1 copy number variationWikiPathways5412

Abacavir ADMEReactomeR-HSA-2161522

Abacavir metabolismReactomeR-HSA-2161541

Abacavir transmembrane transportReactomeR-HSA-2161517

Abasic sugar-phosphate removal via the single-nucleotide replacement pathwayReactomeR-HSA-73930

ABC transporter disordersReactomeR-HSA-5619084

ABC transporters in lipid homeostasisReactomeR-HSA-1369062

ABC-family protein mediated transportReactomeR-HSA-382556

Aberrant regulation of mitotic cell cycle due to RB1 defectsReactomeR-HSA-9687139

Aberrant regulation of mitotic exit in cancer due to RB1 defectsReactomeR-HSA-9687136

Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defectsReactomeR-HSA-9659787

Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarateReactomeR-HSA-2978092

ABO blood group biosynthesisReactomeR-HSA-9033807

Abortive elongation of HIV-1 transcript in the absence of TatReactomeR-HSA-167242

ACE inhibitor pathwayWikiPathways554

Acetaminophen in analgesia and antipyresisWikiPathways5444

AcetylationReactomeR-HSA-156582

Acetylcholine binding and downstream eventsReactomeR-HSA-181431

Acetylcholine inhibits contraction of outer hair cellsReactomeR-HSA-9667769

Acetylcholine Neurotransmitter Release CycleReactomeR-HSA-264642

Acetylcholine regulates insulin secretionReactomeR-HSA-399997

Acetylcholine synthesisWikiPathways528

Acquired partial lipodystrophy Barraquer Simons syndromeWikiPathways5104

Acrosome Reaction and Sperm:Oocyte Membrane BindingReactomeR-HSA-1300645

Acrylamide biotransformation and exposure biomarkersWikiPathways4233

Activated NOTCH1 Transmits Signal to the NucleusReactomeR-HSA-2122948

Activated NTRK2 signals through CDK5ReactomeR-HSA-9032845

Activated NTRK2 signals through FRS2 and FRS3ReactomeR-HSA-9028731

Activated NTRK2 signals through FYNReactomeR-HSA-9032500

Activated NTRK2 signals through PI3KReactomeR-HSA-9028335

Activated NTRK2 signals through PLCG1ReactomeR-HSA-9026527

Activated NTRK2 signals through RASReactomeR-HSA-9026519

Activated NTRK3 signals through PI3KReactomeR-HSA-9603381

Activated NTRK3 signals through PLCG1ReactomeR-HSA-9034793

Activated NTRK3 signals through RASReactomeR-HSA-9034864

Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3ReactomeR-HSA-5625886

Activated point mutants of FGFR2ReactomeR-HSA-2033519

activated TAK1 mediates p38 MAPK activationReactomeR-HSA-450302

Activation and oligomerization of BAK proteinReactomeR-HSA-111452

Activation of AKT2ReactomeR-HSA-165158

Activation of AMPA receptorsReactomeR-HSA-399710

Activation of AMPK downstream of NMDARsReactomeR-HSA-9619483

Activation of anterior HOX genes in hindbrain development during early embryogenesisReactomeR-HSA-5617472

Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteinsReactomeR-HSA-176814

Activation of ATR in response to replication stressReactomeR-HSA-176187

Activation of BAD and translocation to mitochondriaReactomeR-HSA-111447

Activation of BH3-only proteinsReactomeR-HSA-114452

Activation of BIM and translocation to mitochondriaReactomeR-HSA-111446

Activation of BMF and translocation to mitochondriaReactomeR-HSA-139910

Activation of C3 and C5ReactomeR-HSA-174577

Activation of Ca-permeable Kainate ReceptorReactomeR-HSA-451308

Activation of caspases through apoptosome-mediated cleavageReactomeR-HSA-111459

Activation of G protein gated Potassium channelsReactomeR-HSA-1296041

Activation of GABAB receptorsReactomeR-HSA-991365

Activation of gene expression by SREBF (SREBP)ReactomeR-HSA-2426168

Activation of HOX genes during differentiationReactomeR-HSA-5619507

Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE)ReactomeR-HSA-936964

Activation of kainate receptors upon glutamate bindingReactomeR-HSA-451326

Activation of Matrix MetalloproteinasesReactomeR-HSA-1592389

Activation of Na-permeable kainate receptorsReactomeR-HSA-451307

Activation of NF-kappaB in B cellsReactomeR-HSA-1169091

Activation of NIMA Kinases NEK9, NEK6, NEK7ReactomeR-HSA-2980767

Activation of NLRP3 inflammasome by SARS CoV 2WikiPathways4876

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