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A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Compound

(R)-3-aminoisobutyric acid

The (R)-enantiomer of 3-aminoisobutyric acid.

Definition from ChEBI (CHEBI:16320), read 2026-09-23. CC BY 4.0.

CHEBI:16320ChEBI

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What it touches on the way

Inferred

Not reported; assembled from reference reactions.

Mechanistic reach

2 entities

2 entities reached.

0 reported hops2 assembled from the scaffold

AGXT2ProteinUNIPROT:Q9BYV1substrate ofInferred only16 paths8 endpoints
ABATProteinUNIPROT:P80404substrate ofInferred only15 paths15 endpoints

What the reference databases state

Statements

6 statements

6 statements · 1 reference database · Subject: (R)-3-aminoisobutyric acid · Sources: Human-GEM

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(R)-3-aminoisobutyric acid is converted to 2-methyl-3-oxopropanoic acidCompoundHuman-GEM MAR03792Inferred only
2-methyl-3-oxopropanoic acid is converted to (R)-3-aminoisobutyric acidCompoundHuman-GEM MAR03792Inferred only
3-(carbamoylamino)-2-methylpropanoate is converted to (R)-3-aminoisobutyric acidCompoundHuman-GEM MAR04819Inferred only
(R)-3-aminoisobutyric acid is a substrate of ABATProteinHuman-GEM MAR03792Inferred only
(R)-3-aminoisobutyric acid is a substrate of AGXT2ProteinHuman-GEM MAR03792Inferred only
(R)-3-aminoisobutyric acid is a substrate of AGXT2ProteinHuman-GEM MAR03793Inferred only

Reactions

6 reactions

2-methyl-3-oxopropanoic acid+L-glutamate(1-)2-oxoglutarate(2-)+(R)-3-aminoisobutyric acid
Catalysed by AGXT2 or ABAT
Reaction pageReversibleBalancedEC 2.6.1.22, 2.6.1.40GO:0005759
Human-GEM MAR03792CC BY 4.0Reference data
2-methyl-3-oxopropanoic acid+L-alanine(R)-3-aminoisobutyric acid+pyruvate
Catalysed by AGXT2
Reaction pageReversibleBalancedEC 2.6.1.40GO:0005759
Human-GEM MAR03793CC BY 4.0Reference data
3-(carbamoylamino)-2-methylpropanoate+proton+watercarbon dioxide+(R)-3-aminoisobutyric acid+ammonium
Catalysed by UPB1
Reaction pageLeft to rightBalancedEC 3.5.1.6GO:0005829
Human-GEM MAR04819CC BY 4.0Reference data
(R)-3-aminoisobutyric acid(R)-3-aminoisobutyric acid
Reaction pageLeft to rightBalancedGO:0005829, GO:0005615
Human-GEM MAR05020CC BY 4.0Reference data
(R)-3-aminoisobutyric acid(R)-3-aminoisobutyric acid
Reaction pageReversibleBalancedGO:0005829, GO:0005759
Human-GEM MAR07751CC BY 4.0Reference data
(R)-3-aminoisobutyric acid
Reaction pageReversibleBalance undeterminableGO:0005615
Human-GEM MAR09222CC BY 4.0Reference data

Other names

5 names

Resolves to: (R)-3-aminoisobutyric acid

Also called: (R)-3-amino-2-methylpropanoate(R)-beta-aminoisobutyric acid(R)-β-aminoisobutyric acidD-3-Amino-isobutanoate
Systematic name: (2R)-3-amino-2-methylpropanoic acid