Compound
trimethylenediamine
An alkane-α,ω-diamine comprising a propane skeleton with amino substituents at positions 1 and 3.
Definition from ChEBI (CHEBI:15725), read 2026-09-23. CC BY 4.0.
What it touches on the way
Mechanistic reach
6 entities
6 entities reached.
0 reported hops6 assembled from the scaffold
- DHPSProteinUNIPROT:P49366substrate ofInferred only20 paths10 endpoints
- AOC1ProteinUNIPROT:P19801substrate ofInferred only12 paths12 endpoints
- SLC22A2ProteinUNIPROT:O15244transported byInferred only5 paths5 endpoints
- AOC3ProteinUNIPROT:Q16853substrate ofInferred only5 paths5 endpoints
- SLC22A3ProteinUNIPROT:O75751transported byInferred only4 paths4 endpoints
- SLC22A1ProteinUNIPROT:O15245transported byInferred only3 paths3 endpoints
What the reference databases state
Statements
9 statements
9 statements · 1 reference database · Subject: trimethylenediamine · Sources: Human-GEM
- trimethylenediamine is converted to 3-aminopropanalCompoundHuman-GEM MAR07992Inferred only
- trimethylenediamine is a substrate of AOC1ProteinHuman-GEM MAR07992Inferred only
- trimethylenediamine is a substrate of AOC2ProteinHuman-GEM MAR07992Inferred only
- trimethylenediamine is a substrate of AOC3ProteinHuman-GEM MAR07992Inferred only
- trimethylenediamine is a substrate of DHPSProteinHuman-GEM MAR06966Inferred only
- trimethylenediamine is a substrate of DHPSProteinHuman-GEM MAR06967Inferred only
- trimethylenediamine is transported by SLC22A1ProteinHuman-GEM MAR11807Inferred only
- trimethylenediamine is transported by SLC22A2ProteinHuman-GEM MAR11807Inferred only
- trimethylenediamine is transported by SLC22A3ProteinHuman-GEM MAR11807Inferred only
Reactions
6 reactions
trimethylenediamine+MAM00557cMAM01661c
Catalysed by DHPS
Reaction pageReversibleBalancedEC 2.5.1.46GO:0005829
Human-GEM MAR06966CC BY 4.0Reference data
trimethylenediamine+MAM01670cCHEBI:18019+spermidine
Catalysed by DHPS
Reaction pageReversibleBalancedEC 2.5.1.46GO:0005829
Human-GEM MAR06967CC BY 4.0Reference data
water+dioxygen+spermidinetrimethylenediamine+CHEBI:17769+hydrogen peroxide
Reaction pageLeft to rightBalancedGO:0005829
Human-GEM MAR07991CC BY 4.0Reference data
trimethylenediamine+water+dioxygen3-aminopropanal+proton+hydrogen peroxide+ammonium
Catalysed by AOC1 or AOC3 or AOC2
Reaction pageLeft to rightBalancedEC 1.4.3.21, 1.4.3.22GO:0005829
Human-GEM MAR07992CC BY 4.0Reference data
trimethylenediaminetrimethylenediamine
Transported by SLC22A2 or SLC22A3 or SLC22A1
Reaction pageReversibleBalancedGO:0005829, GO:0005615
Human-GEM MAR11807CC BY 4.0Reference data
Reaction pageReversibleBalance undeterminableGO:0005615
Human-GEM MAR11933CC BY 4.0Reference data
Where it reaches
2 systems, 2 regions, 5 tissues, 5 transporter routes — routes, not measurements: transporters known to carry trimethylenediamine are expressed there, and no source reports it arriving.
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Other names
10 names
Resolves to: trimethylenediamine
- Also called
- 1,3-diamino-n-propane1,3-diaminopropane1,3-propanediamine1,3-propylenediamine1,3-trimethylenediamine3-aminopropylaminealpha,omega-propanediaminetnα,ω-propanediamine
- Systematic name
- propane-1,3-diamine