(R)-3-aminoisobutyric acid

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

430 compounds within 3 steps: 2 in 1, 52 in 2, 376 in 3

One step

2-methyl-3-oxopropanoic acidReach from here →
1. (S)-3-amino-2-methylpropionate transaminase (2-methyl-3-oxopropanoate)
Catalysed by ABAT, AGXT2mitochondrial matrixOne of 2 routes
L-alanineReach from here →
1. (R)-3-Amino-2-methylpropanoate:pyruvate aminotransferase
Catalysed by AGXT2mitochondrial matrix

Two steps

CHEBI:1146900Reach from here →
1. (R)-3-Amino-2-methylpropanoate:pyruvate aminotransferase
2. amino-acid N-acetyltransferase (N-acetyl-L-alanine)
Catalysed by AGXT2mitochondrial matrix
N(omega)-methyl-L-arginineReach from here →
1. (R)-3-Amino-2-methylpropanoate:pyruvate aminotransferase
2. N(omega)-methyl-L-arginine + pyruvate = 5-(3-methylguanidino)-2-oxopentanoate + L-alanine
Catalysed by AGXT2mitochondrial matrix
pyruvateReach from here →

(S)-3-amino-2-methylpropionate transaminase (2-methyl-3-oxopropanoate)

(R)-3-Amino-2-methylpropanoate:pyruvate aminotransferase

Catalysed by ABAT, AGXT2mitochondrial matrixOne of 15 routes

propionyl-CoAReach from here →

Catalysed by ABAT, AGXT2, ALDH6A1mitochondrial matrix

CHEBI:15570Reach from here →

Catalysed by AGXT2mitochondrial matrix, cytosol

L-leucineReach from here →

Catalysed by AGXT2, SLC7A5mitochondrial matrix, extracellular space, cytosolOne of 4 routes

CHEBI:15699Reach from here →

Catalysed by AGXT2, SLC7A5mitochondrial matrix, extracellular space, cytosolOne of 3 routes

CHEBI:15971Reach from here →

Catalysed by AGXT2, SLC7A6mitochondrial matrix, extracellular space, cytosolOne of 2 routes

L-cystineReach from here →

Catalysed by AGXT2, SLC7A9, SLC3A1mitochondrial matrix, extracellular space, cytosol

L-citrullineReach from here →

Catalysed by AGXT2, SLC7A6mitochondrial matrix, extracellular space, cytosolOne of 2 routes

L-valineReach from here →

Catalysed by AGXT2, SLC7A5mitochondrial matrix, extracellular space, cytosolOne of 6 routes

L-arginineReach from here →

Catalysed by AGXT2, SLC7A6mitochondrial matrix, extracellular space, cytosolOne of 3 routes

protein polypeptide chainReach from here →

Catalysed by AGXT2mitochondrial matrix, cytosol

CHEBI:16633Reach from here →

Catalysed by AGXT2, SCLYmitochondrial matrix, cytosol

CHEBI:16857Reach from here →

Catalysed by AGXT2, SLC7A5mitochondrial matrix, extracellular space, cytosolOne of 4 routes

L-isoleucineReach from here →

Catalysed by AGXT2, SLC7A5mitochondrial matrix, extracellular space, cytosolOne of 3 routes

CHEBI:17203Reach from here →

Catalysed by AGXT2, SLC7A5mitochondrial matrix, extracellular space, cytosolOne of 3 routes

AH2Reach from here →

Catalysed by AGXT2, MOCOSmitochondrial matrix

L-cysteineReach from here →

Catalysed by AGXT2, SLC7A5mitochondrial matrix, extracellular space, cytosolOne of 11 routes

Ala-tRNA(Ala)Reach from here →

Catalysed by AGXT2, AARS1mitochondrial matrix, cytosol

CHEBI:17895Reach from here →

Catalysed by AGXT2, SLC7A5mitochondrial matrix, extracellular space, cytosolOne of 4 routes

CHEBI:18019Reach from here →

Catalysed by AGXT2, SLC7A6mitochondrial matrix, extracellular space, cytosolOne of 2 routes

L-glutamineReach from here →

Catalysed by AGXT2, SLC3A2, SLC7A5, SLC7A10mitochondrial matrix, extracellular space, cytosolOne of 6 routes

CHEBI:18095Reach from here →

Catalysed by AGXT2, SLC1A4mitochondrial matrix, extracellular space, cytosol

2-aminoisobutanoateReach from here →

Catalysed by AGXT2, SLC7A10mitochondrial matrix, inner side of the membrane, outer side of the membraneOne of 2 routes

N(omega),N('omega)-dimethyl-L-arginineReach from here →

Catalysed by AGXT2mitochondrial matrix

pyridoxine 5'-phosphateReach from here →

Catalysed by AGXT2, SCLYmitochondrial matrix, cytosol

chlorine(.)Reach from here →

Catalysed by AGXT2, SLC6A14mitochondrial matrix, extracellular space, cytosolOne of 2 routes

L-aspartateReach from here →

Catalysed by AGXT2mitochondrial matrix

D-cysteineReach from here →

Catalysed by AGXT2, SLC7A10mitochondrial matrix, inner side of the membrane, outer side of the membraneOne of 2 routes

D-serineReach from here →

Catalysed by AGXT2, SLC7A10mitochondrial matrix, inner side of the membrane, outer side of the membraneOne of 6 routes

L-ornithineReach from here →

Catalysed by AGXT2, SLC7A6mitochondrial matrix, extracellular space, cytosolOne of 3 routes

gamma-Glu-AlaReach from here →

Catalysed by AGXT2, GGT1, GGT5, GGTLC2 and 3 moremitochondrial matrix, extracellular space, cytosol

glycineReach from here →

Catalysed by AGXT2, AGXTmitochondrial matrixOne of 9 routes

(R)-methylmalonyl-CoAReach from here →

Catalysed by ABAT, AGXT2, ALDH6A1mitochondrial matrix

D-alanineReach from here →

Catalysed by AGXT2, SLC7A10mitochondrial matrix, inner side of the membrane, outer side of the membraneOne of 2 routes

D-threonineReach from here →

Catalysed by AGXT2, SLC7A10mitochondrial matrix, inner side of the membrane, outer side of the membraneOne of 2 routes

L-methionineReach from here →

Catalysed by AGXT2, SLC7A5mitochondrial matrix, extracellular space, cytosolOne of 7 routes

L-tryptophanReach from here →

Catalysed by AGXT2, SLC7A5mitochondrial matrix, extracellular space, cytosolOne of 4 routes

L-threonineReach from here →

Catalysed by AGXT2, SLC7A10mitochondrial matrix, inner side of the membrane, outer side of the membraneOne of 4 routes

L-kynurenineReach from here →

Catalysed by AGXT2, KYNUmitochondrial matrix

beta-alanineReach from here →

Catalysed by AGXT2, SLC7A10mitochondrial matrix, inner side of the membrane, outer side of the membraneOne of 2 routes

L-asparagineReach from here →

Catalysed by AGXT2, SLC7A5mitochondrial matrix, extracellular space, cytosolOne of 6 routes

L-phenylalanineReach from here →

Catalysed by AGXT2, SLC7A5mitochondrial matrix, extracellular space, cytosolOne of 6 routes

3-hydroxy-L-kynurenineReach from here →

Catalysed by AGXT2, KYNUmitochondrial matrix

N(omega),N(omega)-dimethyl-L-arginineReach from here →

Catalysed by AGXT2mitochondrial matrix

trans-4-hydroxy-L-prolineReach from here →

Catalysed by AGXT2, SLC1A4mitochondrial matrix, inner side of the membrane, outer side of the membraneOne of 2 routes

(S)-3-amino-2-methylpropanoateReach from here →

Catalysed by ABAT, AGXT2mitochondrial matrix