Compound

alpha-D-glucosamine 6-phosphate

A 2-amino-2-deoxy-D-glucopyranose 6-phosphate that has an α-configuration at the anomeric position.

Definition from ChEBI (CHEBI:15873), read 2026-09-23. CC BY 4.0.

CHEBI:15873ChEBI

Open in the graph

What it touches on the way

Mechanistic reach

3 entities

3 entities reached.

0 reported hops3 assembled from the scaffold

What the reference databases state

Statements

9 statements

9 statements · 2 reference databases · Subject: alpha-D-glucosamine 6-phosphate · Sources: Human-GEM, Rhea

Order

beta-D-fructose 6-phosphate is converted to alpha-D-glucosamine 6-phosphateCompoundRhea RHEA:12172Inferred only
alpha-D-glucosamine 6-phosphate is converted to beta-D-fructose 6-phosphateCompoundRhea RHEA:12172Inferred only
glucosamine is converted to alpha-D-glucosamine 6-phosphateCompoundHuman-GEM MAR04494Inferred only
alpha-D-glucosamine 6-phosphate is converted to keto-D-fructose 6-phosphateCompoundHuman-GEM MAR04299Inferred only
alpha-D-glucosamine 6-phosphate is a substrate of GNPDA1ProteinHuman-GEM MAR04299Inferred only
alpha-D-glucosamine 6-phosphate is a substrate of GNPDA1ProteinRhea RHEA:12172Inferred only
alpha-D-glucosamine 6-phosphate is a substrate of GNPDA2ProteinRhea RHEA:12172Inferred only
alpha-D-glucosamine 6-phosphate is a substrate of GNPDA2ProteinHuman-GEM MAR04299Inferred only
alpha-D-glucosamine 6-phosphate is a substrate of GNPNAT1ProteinHuman-GEM MAR04628Inferred only

Reactions

8 reactions

alpha-D-glucosamine 6-phosphate+waterketo-D-fructose 6-phosphate+proton+ammonium
Catalysed by GNPDA1 or GNPDA2
Reaction pageLeft to rightBalancedEC 3.5.99.6cytosol
Human-GEM MAR04299CC BY 4.0Reference data
keto-D-fructose 6-phosphate+L-glutaminealpha-D-glucosamine 6-phosphate+L-glutamate(1-)
Catalysed by GFPT2 or GFPT1
Reaction pageLeft to rightBalancedEC 2.6.1.16cytosol
Human-GEM MAR04300CC BY 4.0Reference data
ATP+glucosamineADP+alpha-D-glucosamine 6-phosphate+proton
Catalysed by GCK or HKDC1 or HK1 or HK2 or HK3
Reaction pageLeft to rightBalancedEC 2.7.1.1cytosol
Human-GEM MAR04494CC BY 4.0Reference data
glucosamine+CHEBI:16039alpha-D-glucosamine 6-phosphate+proton+CHEBI:17808
Catalysed by HK1 or HK2
Reaction pageLeft to rightBalancedEC 2.7.1.1cytosol
Human-GEM MAR04495CC BY 4.0Reference data
CHEBI:16284+glucosamineCHEBI:16174+alpha-D-glucosamine 6-phosphate+proton
Catalysed by HKDC1 or HK1 or HK2
Reaction pageLeft to rightBalancedEC 2.7.1.1cytosol
Human-GEM MAR04496CC BY 4.0Reference data
CHEBI:15351+alpha-D-glucosamine 6-phosphateCHEBI:1146900+proton+N-acetyl-D-glucosamine 6-phosphate
Catalysed by GNPNAT1
Reaction pageLeft to rightBalancedEC 2.3.1.4cytosol
Human-GEM MAR04628CC BY 4.0Reference data
water+N-acetyl-D-glucosamine 6-phosphateacetate+alpha-D-glucosamine 6-phosphate
Catalysed by AMDHD2 or CEMP1
Reaction pageLeft to rightBalancedEC 3.5.1.25cytosol
Human-GEM MAR04629CC BY 4.0Reference data
alpha-D-glucosamine 6-phosphate+waterbeta-D-fructose 6-phosphate+ammonium
Catalysed by GNPDA1 or GNPDA2
Reaction pageReversibleBalanced
Rhea RHEA:12172CC BY 4.0Reference data

Other names

7 names

Resolves to: alpha-D-glucosamine 6-phosphate

Also called: 2-amino-2-deoxy-6-O-phosphono-alpha-D-glucopyranose2-amino-2-deoxy-6-O-phosphono-α-D-glucopyranosealpha-D-glucosamine 6-(dihydrogen phosphate)GLUCOSAMINE 6-PHOSPHATEα-D-glucosamine 6-(dihydrogen phosphate)
Systematic name: 2-amino-2-deoxy-alpha-D-glucopyranose 6-(dihydrogen phosphate)2-amino-2-deoxy-α-D-glucopyranose 6-(dihydrogen phosphate)