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Proteins/UNIPROT:O15067
Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate..
Function from UniProtKB (O15067), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 1 · substrate of
1 compound
1 compound.
0 reported routes1 assembled route
183 statements
183 statements · 6 reference databases · Subject: PFAS · Sources: Hetionet, Human Protein Atlas, Human-GEM, Reactome, Rhea, WikiPathways
2 reactions
ATP+L-glutamine+water+N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide2-formamido-N(1)-(5-phospho-D-ribosyl)acetamidine+ADP+L-glutamate(1-)+proton+phosphate(3-)
Catalysed by PFAS
Reaction pageLeft to rightBalancedEC 6.3.5.3cytosol
Human-GEM MAR04808CC BY 4.0Reference data
8 names
Resolves to: PFAS
Catalysed by PFAS
Reaction pageLeft to rightBalanced
Rhea RHEA:17129CC BY 4.0Reference data