urea

• cationic amino acid transporter-2 and C/EBPbeta mRNA in liver

  increases

  Cationic amino acid transporter-2 and C/EBPbeta mRNAs were also highly increased

  PMID:10652239 · one of two readings recorded this

• iNOS mRNA in liver

  increases

  When rats were injected intraperitoneally with LPS, iNOS mRNA was markedly induced

  PMID:10652239 · one of two readings recorded this

• mRNAs of urea cycle enzymes except ornithine transcarbamylase

  decreases

  mRNAs for all the urea cycle enzymes except ornithine transcarbamylase were gradually decreased and reached 16-28% of controls at 12 h

  PMID:10652239 · one of two readings recorded this

• urea cycle enzyme protein levels

  no effect

  However, all these enzymes remained unchanged at protein level up to 24 h

  PMID:10652239 · one of two readings recorded this

• adriamycin- and light-induced lipid and lipoprotein changes

  modulates

  All changes induced by adriamycin and constant light were reverted toward normality by melatonin administration

  PMID:12435086 · one of two readings recorded this

• LDL-c increase and HDL-c decrease

  modulates

  Constant light exposure also prompted an increase in LDL-c levels and a decrease in HDL-c values, and intensified the effects of adriamycin on these two lipoproteins

  PMID:12435086 · one of two readings recorded this

• melatonin levels in serum and kidney

  decreases

  Results show a decrease in melatonin levels induced by both adriamycin and constant light

  PMID:12435086 · one of two readings recorded this

• triglycerides, total cholesterol and LDL cholesterol

  increases

  adriamycin induced significant increases in triglycerides, total cholesterol and light-density lipoprotein cholesterol, and lowered high-density lipoprotein cholesterol levels

  PMID:12435086 · one of two readings recorded this

• inulin clearance

  no effect

  No differences were observed in inulin (0.28+/-0.08 vs 0.25+/-0.08 ml/min/100 g; P=NS) or creatinine clearance rates

  PMID:12543878 · one of two readings recorded this

• serum creatine and intramuscular total creatine concentrations

  increases, p = 0.05

  Serum creatine and intramuscular total creatine concentrations were higher in creatine-supplemented groups (P<0.05)

  PMID:12543878 · one of two readings recorded this

• urea clearance

  no effect

  Serum cystatin C concentration, urinary protein excretion, and albumin and urea clearance were comparable between creatine-supplemented and control-diet fed animals in both sham-operated and two-thirds nephrectomized animals

  PMID:12543878 · one of two readings recorded this

• urea production by bovine pulmonary arterial endothelial cells under L-valine, L-arginine

  decreases, L-Val decreased urea production, concentration-dependent

  Not recorded as a finding: the compound is what was measured, not what was given

  Addition of L-Val to the medium led to a concentration-dependent decrease in urea production and a concentration-dependent increase in NO production in both control and L/T-treated bPAEC.

  PMID:14977627 · one of two readings recorded this

• urea production

  increases

  Treatment with L-Arg increased both urea and NO production

  PMID:14977627 · one of two readings recorded this

• urea production

  decreases

  In both control and L/T bPAEC, treatment with L-Val decreased urea production and increased NO production

  PMID:14977627 · one of two readings recorded this

• urea production

  decreases

  The addition of the combination L-Arg and L-Val decreased urea production compared with the addition of L-Arg alone

  PMID:14977627 · one of two readings recorded this

• urea production

  decreases

  Addition of L-Val to the medium led to a concentration-dependent decrease in urea production and a concentration-dependent increase in NO production in both control and L/T-treated bPAEC

  PMID:14977627 · one of two readings recorded this

• average daily weight gain

  increases, p = 0.05

  enhanced (P < 0.05) average daily weight gain by 28 and 66%, and body weight by 15 and 32%

  PMID:14988458 · one of two readings recorded this

• average daily weight gain

  increases, p = 0.05

  enhanced (P < 0.05) average daily weight gain by 28 and 66%, and body weight by 15 and 32%

  PMID:14988458 · one of two readings recorded this

• body weight

  increases, p = 0.05

  enhanced (P < 0.05) average daily weight gain by 28 and 66%, and body weight by 15 and 32%

  PMID:14988458 · one of two readings recorded this

• body weight

  increases, p = 0.05

  enhanced (P < 0.05) average daily weight gain by 28 and 66%, and body weight by 15 and 32%

  PMID:14988458 · one of two readings recorded this

• food intake

  no effect

  Food intake did not differ between control and arginine-supplemented piglets [66.7 vs. 69.5 g dry matter/(kg body wt. d)]

  PMID:14988458 · one of two readings recorded this

• plasma ammonia concentration

  decreases, p = 0.05

  decreased (P < 0.05) plasma concentrations of ammonia by 20 and 35%, and those of urea by 19 and 33%

  PMID:14988458 · one of two readings recorded this

• plasma ammonia concentration

  decreases, p = 0.05

  decreased (P < 0.05) plasma concentrations of ammonia by 20 and 35%, and those of urea by 19 and 33%

  PMID:14988458 · one of two readings recorded this

• plasma arginine concentration

  increases, p = 0.05

  increased (P < 0.05) plasma concentrations of arginine by 30 and 61%

  PMID:14988458 · one of two readings recorded this

• plasma arginine concentration

  increases, p = 0.05

  increased (P < 0.05) plasma concentrations of arginine by 30 and 61%

  PMID:14988458 · one of two readings recorded this

• plasma insulin and growth hormone concentrations

  increases, p = 0.05

  Dietary supplementation with 0.4% L-arginine also increased (P < 0.05) plasma concentrations of insulin and growth hormone by 24-27% in piglets

  PMID:14988458 · one of two readings recorded this

• plasma urea concentration

  decreases, p = 0.05

  decreased (P < 0.05) plasma concentrations of ammonia by 20 and 35%, and those of urea by 19 and 33%

  PMID:14988458 · one of two readings recorded this

• plasma urea concentration

  decreases, p = 0.05

  decreased (P < 0.05) plasma concentrations of ammonia by 20 and 35%, and those of urea by 19 and 33%

  PMID:14988458 · one of two readings recorded this

• ureagenesis

  increases

  ureagenesis (approximately 130%, EC50 7.0 x 10(-8) M)

  PMID:16352677 · one of two readings recorded this

• kidney MDA

  decreases

  Diet supplemented with Flax and Pumpkin seeds mixture ameliorated the antioxidant enzymes activities observed in diabetic rats and significantly decreased MDA levels

  PMID:20570704 · one of two readings recorded this

• bladder cancer susceptibility, rs10775480/rs10853535 (SLC14A1, 18q12.3)

  increases

  rs10775480/rs10853535 (r(2)= 1.00; P = 8.9 × 10(-9); allelic odds ratio 1.16 with 95% CI: 1.10-1.22)

  PMID:21824976 · one of two readings recorded this

• bladder cancer susceptibility, rs7238033 (SLC14A1, 18q12.3)

  increases

  rs7238033 (P = 8.7 × 10(-9); allelic odds ratio 1.20 with 95% CI: 1.13-1.28)

  PMID:21824976 · one of two readings recorded this

• serum urea in cisplatin-injected rats, standard diagnostic kit

  decreases, urea lower with rosuvastatin than cisplatin alone

  Not recorded as a finding: the compound is what was measured, not what was given

  The treatment with RST showed highly significant decrease in BUN (P < 0.001), urea (P < 0.001), creatinine (P < 0.01) and significant increase in albumin (P < 0.001) as compared to CIS-treated group.

  PMID:24014910 · one of two readings recorded this

• serum urea

  increases, p = 0.001

  significant (P < 0.001) increase in serum urea, BUN, creatinine, uric acid

  PMID:24014910 · one of two readings recorded this

• serum urea

  decreases, p = 0.001

  The treatment with RST showed highly significant decrease in BUN (P < 0.001), urea (P < 0.001), creatinine (P < 0.01)

  PMID:24014910 · one of two readings recorded this

• serum urea

  decreases, p = 0.01

  The treatment with SIM showed significant decrease in BUN (P < 0.01), urea (P < 0.01), and creatinine (P < 0.05)

  PMID:24014910 · one of two readings recorded this

• antioxidant enzyme activities, MDA and carbonyl levels after cisplatin plus riboflavin

  decreases

  Hence, this study reveals that cisplatin is more toxic in male mice and the ameliorative effect of riboflavin against cisplatin toxicity is stronger in female mice

  PMID:25242266 · one of two readings recorded this

• glycated haemoglobin (HbA1c)

  decreases, significant reduction in HbA1c with coenzyme Q10

  The diabetic rats treated with coenzyme Q10 showed a significant (P < 0.05) reduction in HbA1C level as compared to diabetic control rats.

  PMID:25538335 · one of two readings recorded this

• glycated hemoglobin (HbA1c)

  decreases, p = 0.05

  The diabetic rats treated with coenzyme Q10 showed a significant (P < 0.05) reduction in HbA1C level as compared to diabetic control rats.

  PMID:25538335 · one of two readings recorded this

• renal TNF-alpha, MPO activity and TGF-beta

  decreases

  The treatment with coenzyme Q10 in STZ-nicotinamide treated rats showed a significant reduction in TNF-α (P < 0.001) level, MPO activity (P < 0.05) and TGF-β (P < 0.01) in renal tissue when compared to diabetic control rats.

  PMID:25538335 · one of two readings recorded this

• renal TNF-alpha, myeloperoxidase (MPO) activity, TGF-beta

  decreases, significant reduction in TNF-alpha, MPO activity and TGF-beta versus diabetic control

  The treatment with coenzyme Q10 in STZ-nicotinamide treated rats showed a significant reduction in TNF-α (P < 0.001) level, MPO activity (P < 0.05) and TGF-β (P < 0.01) in renal tissue when compared to diabetic control rats.

  PMID:25538335 · one of two readings recorded this

• serum urea concentration by standard diagnostic kit

  decreases, significant reduction in urea levels with coenzyme Q10, metformin, or their combination compared to diabetic control rats

  Not recorded as a finding: the compound is what was measured, not what was given

  The treatment with coenzyme Q10, metformin or coenzyme Q10 + metformin showed a significant (P < 0.01; P < 0.05 and P < 0.001) reduction in urea levels as compared to diabetic control rats.

  PMID:25538335 · one of two readings recorded this

• serum urea concentration, standard diagnostic kit assay

  decreases, significant reduction in serum urea levels with coenzyme Q10, metformin, or the combination versus diabetic control rats

  Not recorded as a finding: the compound is what was measured, not what was given

  The treatment with coenzyme Q10, metformin or coenzyme Q10 + metformin showed a significant (P < 0.01; P < 0.05 and P < 0.001) reduction in urea levels as compared to diabetic control rats.

  PMID:25538335 · one of two readings recorded this

• serum urea

  decreases

  The treatment with coenzyme Q10, metformin or coenzyme Q10 + metformin showed a significant (P < 0.01; P < 0.05 and P < 0.001) reduction in urea levels as compared to diabetic control rats.

  PMID:25538335 · both readings recorded this

• negative likelihood ratio

  Likelihood ratio for a positive test was 12 and for a negative test was 0.05 with an area under thecurve of 0.985

  PMID:25632206 · one of two readings recorded this

• positive likelihood ratio

  Likelihood ratio for a positive test was 12 and for a negative test was 0.05 with an area under thecurve of 0.985

  PMID:25632206 · one of two readings recorded this

• area under the curve

  Likelihood ratio for a positive test was 12 and for a negative test was 0.05 with an area under thecurve of 0.985

  PMID:25632206 · one of two readings recorded this

• pooled sensitivity of urea breath test for H. pylori

  Pooled sensitivity was 0.96 (95%CI: 0.95-0.97)

  PMID:25632206 · one of two readings recorded this

• pooled specificity of urea breath test for H. pylori

  andpooled specificity was 0.93 (95%CI: 0.91-0.94)

  PMID:25632206 · one of two readings recorded this

• plasma urea

  no effect, p = 0.05

  creatinine, urea, and creatinine clearance, compared to control group (p> 0.05)

  PMID:26016930 · one of two readings recorded this

• pooled sensitivity of 13C-UBT for H. pylori

  the summary estimate for sensitivity was 97% (95% CI: 96, 98%)

  PMID:31348624 · one of two readings recorded this

• pooled sensitivity

  100 mg | 5 | 0.07 (53.0%) | <0.01 (76.1%) | 0.98 (0.97, 0.99) | 0.94 (0.92, 0.96)

  PMID:31348624 · one of two readings recorded this

• pooled sensitivity

  50 mg | 4 | 0.24# (28.7%) | 0.17# (40.6%) | 1.00 (0.98, 1.00) | 0.99 (0.96, 1.00)

  PMID:31348624 · one of two readings recorded this

• pooled sensitivity

  75 mg | 4 | 0.01 (76.5%) | 0.28# (21.0%) | 0.93 (0.90, 0.96) | 0.96 (0.94, 0.98)

  PMID:31348624 · one of two readings recorded this

• pooled sensitivity

  10 to 15 minutes | 5 | <0.01 (83.0%) | 0.06 (55.4%) | 0.96 (0.94, 0.98) | 0.94 (0.90, 0.96)

  PMID:31348624 · one of two readings recorded this

• pooled sensitivity

  20 minutes | 5 | 0.26# (24.0%) | 0.15# (40.3%) | 0.99 (0.98, 1.00) | 0.99 (0.97, 1.00)

  PMID:31348624 · one of two readings recorded this

• pooled sensitivity

  30 minutes | 5 | 0.07 (54.6%) | 0.10# (48.4%) | 0.96 (0.94, 0.97) | 0.96 (0.94, 0.98)

  PMID:31348624 · one of two readings recorded this

• pooled sensitivity

  <5.0 δ over baseline | 9 | 0.02 (54.4%) | <0.01 (75.9%) | 0.98 (0.97, 0.99) | 0.96 (0.95, 0.97)

  PMID:31348624 · one of two readings recorded this

• pooled sensitivity

  Hong Kong | 6 | <0.01 (75.5%) | 0.36# (8.4%) | 0.96 (0.94, 0.98) | 0.98 (0.96, 0.99)

  PMID:31348624 · one of two readings recorded this

• pooled sensitivity

  Taiwan | 5 | 0.13# (44.0%) | 0.06 (54.8%) | 0.98 (0.96, 0.99) | 0.93 (0.91, 0.96)

  PMID:31348624 · one of two readings recorded this

• pooled sensitivity

  13C-UBT (INER, Taiwan) | 5 | 0.13# (44.0%) | 0.06 (54.8%) | 0.98 (0.96, 0.99) | 0.93 (0.91, 0.96)

  PMID:31348624 · one of two readings recorded this

• pooled sensitivity

  Others | 10 | <0.01 (77.5%) | 0.05 (46.7%) | 0.96 (0.94, 0.97) | 0.98 (0.97, 0.99)

  PMID:31348624 · one of two readings recorded this

• pooled specificity of 13C-UBT for H. pylori

  and specificity was 96% (95% CI: 95, 97%)

  PMID:31348624 · one of two readings recorded this

• pooled specificity

  100 mg | 5 | 0.07 (53.0%) | <0.01 (76.1%) | 0.98 (0.97, 0.99) | 0.94 (0.92, 0.96)

  PMID:31348624 · one of two readings recorded this

• pooled specificity

  50 mg | 4 | 0.24# (28.7%) | 0.17# (40.6%) | 1.00 (0.98, 1.00) | 0.99 (0.96, 1.00)

  PMID:31348624 · one of two readings recorded this

• pooled specificity

  75 mg | 4 | 0.01 (76.5%) | 0.28# (21.0%) | 0.93 (0.90, 0.96) | 0.96 (0.94, 0.98)

  PMID:31348624 · one of two readings recorded this

• pooled specificity

  10 to 15 minutes | 5 | <0.01 (83.0%) | 0.06 (55.4%) | 0.96 (0.94, 0.98) | 0.94 (0.90, 0.96)

  PMID:31348624 · one of two readings recorded this

• pooled specificity

  20 minutes | 5 | 0.26# (24.0%) | 0.15# (40.3%) | 0.99 (0.98, 1.00) | 0.99 (0.97, 1.00)

  PMID:31348624 · one of two readings recorded this

• pooled specificity

  30 minutes | 5 | 0.07 (54.6%) | 0.10# (48.4%) | 0.96 (0.94, 0.97) | 0.96 (0.94, 0.98)

  PMID:31348624 · one of two readings recorded this

• pooled specificity

  <5.0 δ over baseline | 9 | 0.02 (54.4%) | <0.01 (75.9%) | 0.98 (0.97, 0.99) | 0.96 (0.95, 0.97)

  PMID:31348624 · one of two readings recorded this

• pooled specificity

  Hong Kong | 6 | <0.01 (75.5%) | 0.36# (8.4%) | 0.96 (0.94, 0.98) | 0.98 (0.96, 0.99)

  PMID:31348624 · one of two readings recorded this

• pooled specificity

  Taiwan | 5 | 0.13# (44.0%) | 0.06 (54.8%) | 0.98 (0.96, 0.99) | 0.93 (0.91, 0.96)

  PMID:31348624 · one of two readings recorded this

• pooled specificity

  13C-UBT (INER, Taiwan) | 5 | 0.13# (44.0%) | 0.06 (54.8%) | 0.98 (0.96, 0.99) | 0.93 (0.91, 0.96)

  PMID:31348624 · one of two readings recorded this

• pooled specificity

  Others | 10 | <0.01 (77.5%) | 0.05 (46.7%) | 0.96 (0.94, 0.97) | 0.98 (0.97, 0.99)

  PMID:31348624 · one of two readings recorded this

• sensitivity

  n = 100

  5. | Chua (2002) | 100 | 65 | 31 | 0 | 4 | 94.2 | 100.0 | 96.0 | 100.0 | 88.6

  PMID:31348624 · one of two readings recorded this

• sensitivity

  n = 220

  6. | Kato (2002) | 220 | i87 | i129 | i2 | i2 | 97.8 | 98.5 | 98.2 | 97.8 | 98.5

  PMID:31348624 · one of two readings recorded this

• sensitivity

  n = 136

  9. | Peng (2000) | 136 | i76 | i49 | i6 | i5 | 93.8 | 89.1 | 91.9 | 92.7 | 90.7

  PMID:31348624 · one of two readings recorded this

• sensitivity

  n = 50

  2. | Peng (2005a) | 50 | 27 | 22 | 0 | 1 | 96.4 | 100.0 | 98.0 | 100.0 | 95.6

  PMID:31348624 · one of two readings recorded this

• sensitivity

  n = 50

  Peng (2005b) | 50 | 18 | 32 | 0 | 0 | 100.0 | 100.0 | 100.0 | 100.0 | 100.0

  PMID:31348624 · one of two readings recorded this

• sensitivity

  n = 127

  3. | Urita (2004) | 127 | i42 | i85 | i0 | i0 | 100.0 | 100.0 | 100.0 | 100.0 | 100.0

  PMID:31348624 · one of two readings recorded this

• sensitivity

  n = 352

  11. | Wang (1998a) | 352 | 197 | 143 | 10 | 2 | 99.0 | 93.4 | 96.6 | 95.2 | 98.6

  PMID:31348624 · one of two readings recorded this

• sensitivity

  n = 352

  Wang (1998b) | 352 | 196 | 142 | 11 | 3 | 98.5 | 92.8 | 96.0 | 94.7 | 97.9

  PMID:31348624 · one of two readings recorded this

• sensitivity

  n = 76

  1. | Wardi (2012) | 76 | i9 | i57 | i5 | i5 | 64.2 | 91.9 | 86.8 | 64.2 | 91.9

  PMID:31348624 · one of two readings recorded this

• sensitivity

  n = 202

  10. | Wong (2000a) | 202 | i110 | i86 | i2 | i4 | 96.5 | 97.7 | 97.0 | 98.2 | 95.6

  PMID:31348624 · one of two readings recorded this

• sensitivity

  n = 202

  Wong (2000b) | 202 | i108 | i86 | i2 | i6 | 94.7 | 97.7 | 96.0 | 98.2 | 93.5

  PMID:31348624 · one of two readings recorded this

• sensitivity

  n = 200

  4. | Wong (2003) | 200 | i99 | i101 | i0 | i0 | 100.0 | 100.0 | 100.0 | 100.0 | 100.0

  PMID:31348624 · one of two readings recorded this

• sensitivity

  n = 294

  8. | Wong BCY (2001) | 294 | i151 | i127 | i4 | i12 | 92.6 | 96.9 | 94.5 | 97.4 | 91.2

  PMID:31348624 · one of two readings recorded this

• sensitivity

  n = 101

  7. | Wong WM (2001a) | 101 | i49 | i50 | i2 | i0 | 100.0 | 96.2 | 98.0 | 96.1 | 100.0

  PMID:31348624 · one of two readings recorded this

• sensitivity

  n = 105

  Wong WM (2001b) | 105 | i50 | i54 | i1 | i0 | 100.0 | 98.2 | 99.1 | 98.0 | 100.0

  PMID:31348624 · one of two readings recorded this

• specificity

  n = 100

  5. | Chua (2002) | 100 | 65 | 31 | 0 | 4 | 94.2 | 100.0 | 96.0 | 100.0 | 88.6

  PMID:31348624 · one of two readings recorded this

• specificity

  n = 220

  6. | Kato (2002) | 220 | i87 | i129 | i2 | i2 | 97.8 | 98.5 | 98.2 | 97.8 | 98.5

  PMID:31348624 · one of two readings recorded this

• specificity

  n = 136

  9. | Peng (2000) | 136 | i76 | i49 | i6 | i5 | 93.8 | 89.1 | 91.9 | 92.7 | 90.7

  PMID:31348624 · one of two readings recorded this

• specificity

  n = 50

  2. | Peng (2005a) | 50 | 27 | 22 | 0 | 1 | 96.4 | 100.0 | 98.0 | 100.0 | 95.6

  PMID:31348624 · one of two readings recorded this

• specificity

  n = 50

  Peng (2005b) | 50 | 18 | 32 | 0 | 0 | 100.0 | 100.0 | 100.0 | 100.0 | 100.0

  PMID:31348624 · one of two readings recorded this

• specificity

  n = 127

  3. | Urita (2004) | 127 | i42 | i85 | i0 | i0 | 100.0 | 100.0 | 100.0 | 100.0 | 100.0

  PMID:31348624 · one of two readings recorded this

• specificity

  n = 352

  11. | Wang (1998a) | 352 | 197 | 143 | 10 | 2 | 99.0 | 93.4 | 96.6 | 95.2 | 98.6

  PMID:31348624 · one of two readings recorded this

• specificity

  n = 352

  Wang (1998b) | 352 | 196 | 142 | 11 | 3 | 98.5 | 92.8 | 96.0 | 94.7 | 97.9

  PMID:31348624 · one of two readings recorded this

• specificity

  n = 76

  1. | Wardi (2012) | 76 | i9 | i57 | i5 | i5 | 64.2 | 91.9 | 86.8 | 64.2 | 91.9

  PMID:31348624 · one of two readings recorded this

• specificity

  n = 202

  10. | Wong (2000a) | 202 | i110 | i86 | i2 | i4 | 96.5 | 97.7 | 97.0 | 98.2 | 95.6

  PMID:31348624 · one of two readings recorded this

• specificity

  n = 202

  Wong (2000b) | 202 | i108 | i86 | i2 | i6 | 94.7 | 97.7 | 96.0 | 98.2 | 93.5

  PMID:31348624 · one of two readings recorded this

• specificity

  n = 200

  4. | Wong (2003) | 200 | i99 | i101 | i0 | i0 | 100.0 | 100.0 | 100.0 | 100.0 | 100.0

  PMID:31348624 · one of two readings recorded this

• specificity

  n = 294

  8. | Wong BCY (2001) | 294 | i151 | i127 | i4 | i12 | 92.6 | 96.9 | 94.5 | 97.4 | 91.2

  PMID:31348624 · one of two readings recorded this

• specificity

  n = 101

  7. | Wong WM (2001a) | 101 | i49 | i50 | i2 | i0 | 100.0 | 96.2 | 98.0 | 96.1 | 100.0

  PMID:31348624 · one of two readings recorded this

• specificity

  n = 105

  Wong WM (2001b) | 105 | i50 | i54 | i1 | i0 | 100.0 | 98.2 | 99.1 | 98.0 | 100.0

  PMID:31348624 · one of two readings recorded this

• correlation between rate of blood ammonia increase and total running time

  decreases, r = -0.57, p = 0.05, n = 19

  The rate of increase of blood ammonia concentration was significantly negatively correlated with total running time, which was measured as an index of exercise endurance capacity (r = −0.57, P < 0.05).

  PMID:32269254 · one of two readings recorded this

• energy metabolism (respiratory exchange ratio, fat and carbohydrate expenditure) under chronic hyperammonaemia

  increases

  we did observe significantly increased respiratory exchange ratio, significantly decreased fat expenditure, and significantly increased carbohydrate expenditure during the day.

  PMID:32269254 · one of two readings recorded this

• exercise time to exhaustion (endurance capacity)

  increases, GTC plus training improved endurance versus training alone

  Four weeks of continuous oral administration of GTCs and training intervention significantly improved exercise endurance in mice, whereas no improvement was observed in the mice subjected to training alone (control group).

  PMID:32269254 · one of two readings recorded this

• liver ammonia concentration after GTC intake

  decreases, n = 7

  Administration of GTCs did not change the amount of ammonia in the gastrocnemius muscle, but it did significantly decrease the amount of ammonia in the liver.

  PMID:32269254 · one of two readings recorded this

• liver ammonia concentration

  decreases, GTCs significantly decreased liver ammonia, no change in muscle ammonia

  Administration of GTCs did not change the amount of ammonia in the gastrocnemius muscle, but it did significantly decrease the amount of ammonia in the liver.

  PMID:32269254 · one of two readings recorded this

• mitochondrial OCR in C2C12 myotubes pre-incubated with GTCs then exposed to ammonium chloride

  increases, n = 6

  Exposure to 5 mM ammonium chloride significantly decreased OCR in the C2C12 myotubes, and exposure to 0.01%, but not 0.001%, GTCs rescued the ammonium chloride-induced reduction in OCR.

  PMID:32269254 · one of two readings recorded this

• mitochondrial oxygen consumption rate (OCR) in C2C12 myotubes and soleus under ammonium chloride exposure

  decreases

  Administration of 5 mM ammonium chloride significantly suppressed OCR compared with control in C2C12 myotubes and soleus, but not in extensor digitorum longus.

  PMID:32269254 · one of two readings recorded this

• mitochondrial oxygen consumption rate (OCR) in C2C12 myotubes

  increases, GTC pre-incubation increased OCR and rescued ammonium-chloride-induced suppression

  Pre-incubation of the muscle cells with 0.01% GTCs significantly increased OCR in C2C12 myotubes compared with control.

  PMID:32269254 · one of two readings recorded this

• running time to exhaustion after GTC intake plus exercise training

  increases, n = 7

  Four weeks of continuous oral administration of GTCs and training intervention significantly improved exercise endurance in mice, whereas no improvement was observed in the mice subjected to training alone (control group).

  PMID:32269254 · one of two readings recorded this

• urea-cycle enzyme gene expression (Cps1, Otc, Ass1, Arg1, Nags, Asl) in primary mouse liver cells treated with GTCs

  increases, n = 4

  GTC treatment significantly increased the expression of Cps1, Otc, Ass1, and Arg1, but significantly decreased the expression of Nags and Asl, compared with control.

  PMID:32269254 · one of two readings recorded this

• urea-cycle enzyme gene expression (Nags, Cps1, Asl, Arg1) in mouse liver after 8-week GTC intake

  increases, n = 8

  ingestion of GTCs significantly increased the expression of Nags, Cps1, Asl, and Arg1, compared with control; the expression of Otc tended to increase (P = 0.07) and the expression of Ass1 remained unchanged.

  PMID:32269254 · one of two readings recorded this

• urea cycle enzyme gene expression (Nags, Cps1, Otc, Ass1, Asl, Arg1) in liver

  increases, increased Nags, Cps1, Asl, Arg1; Otc trend; Ass1 unchanged

  ingestion of GTCs significantly increased the expression of Nags, Cps1, Asl, and Arg1, compared with control; the expression of Otc tended to increase (P = 0.07) and the expression of Ass1 remained unchanged.

  PMID:32269254 · one of two readings recorded this

• urea cycle enzyme gene expression (Nags, Cps1, Otc, Ass1, Asl, Arg1) in mouse liver by qRT-PCR

  increases, increased expression of Nags, Cps1, Asl and Arg1; Otc trended up (P = 0.07); Ass1 unchanged

  Not recorded as a finding: subject_absent

  ingestion of GTCs significantly increased the expression of Nags, Cps1, Asl, and Arg1, compared with control; the expression of Otc tended to increase (P = 0.07) and the expression of Ass1 remained unchanged.

  PMID:32269254 · one of two readings recorded this

• decrease in conformational stability, modified alpha-crystallin

  decreases

  The decrease in conformational stability is estimated to be 0.22- and 0.92 kcal mol-1 for modified alpha- and gamma-II crystallin, respectively

  PMID:3409984 · one of two readings recorded this

• decrease in conformational stability, modified gamma-II crystallin

  decreases

  The decrease in conformational stability is estimated to be 0.22- and 0.92 kcal mol-1 for modified alpha- and gamma-II crystallin, respectively

  PMID:3409984 · one of two readings recorded this

• proteolytic degradation rate

  increases

  Proteolytic digestion also shows a faster rate of degradation for the modified crystallins

  PMID:3409984 · one of two readings recorded this

• urea and Gdn-HCl denaturation curve midpoint

  decreases

  The denaturation curves of both urea and Gdn-HCl shift to lower denaturant concentration for crystallins of glutathione mixed disulfide

  PMID:3409984 · one of two readings recorded this

• AUC of BUN/albumin ratio for mortality

  n = 433

  Alirezaei (2022) | 72 vs 56 | 63 vs 60 | 433 | 0.733 | 75.8/70.8 | 4.94 | Mortality | Iran

  PMID:36800572 · one of two readings recorded this

• AUC of BUN/albumin ratio for mortality

  n = 358

  Ata (2021) † | 66 vs 48 | 44 vs 39 | 358 | 0.823 | 74.5/75.6 | 3.4 | Mortality | Turkey

  PMID:36800572 · one of two readings recorded this

• AUC of BUN/albumin ratio for mortality

  n = 602

  Kucukceran (2021) | 75 vs 60 | 66 vs 49 | 602 | 0.809 | 87.5/59.9 | 3.9 | Mortality | Turkey

  PMID:36800572 · one of two readings recorded this

• AUC of BUN/albumin ratio for mortality

  n = 131

  Singh (2022) | 56 vs 53 | 31 vs 69 | 131 | 0.695 | 79/54 | 6.23 | Mortality | India

  PMID:36800572 · one of two readings recorded this

• AUC of BUN/albumin ratio for severity

  n = 609

  Gemcioglu (2021) | 68 vs 46 | 56 vs 57 | 609 | 0.795 | 63.37/84.89 | 4.83 | Severity | Turkey

  PMID:36800572 · one of two readings recorded this

• AUC of BUN/albumin ratio for severity

  n = 1370

  Huang (2021) | 67 vs 54 | 62 vs 44 | 1370 | 0.821 | 69/78.6 | 3.79 | Severity | China

  PMID:36800572 · one of two readings recorded this

• BUN/albumin ratio, poor vs good prognosis

  increases, p = 0.001

  Mean difference: 2.838, 95% CI: 2.015–3.66, P <.001, I2 = 92.5%, 7 studies

  PMID:36800572 · one of two readings recorded this

• pooled area under the sROC curve for poor prognosis

  an AUC of 0.81 (95% CI = 0.77–0.84)

  PMID:36800572 · one of two readings recorded this

• pooled sensitivity for poor prognosis

  0.76 (95% CI = 0.68–0.82; I2 = 70.59%)

  PMID:36800572 · one of two readings recorded this

• pooled specificity for poor prognosis

  0.72 (95% CI = 0.63–0. 8; I2 = 95.79%)

  PMID:36800572 · one of two readings recorded this

• risk of poor prognosis, high vs low BUN/albumin ratio

  increases, p = 0.001

  OR: 3.009, 95% CI: 1.565–5.783, P =.001, I2 = 93.7%

  PMID:36800572 · one of two readings recorded this

• sensitivity of BUN/albumin ratio at study cut-off

  n = 433

  Alirezaei (2022) | 72 vs 56 | 63 vs 60 | 433 | 0.733 | 75.8/70.8 | 4.94 | Mortality | Iran

  PMID:36800572 · one of two readings recorded this

• sensitivity of BUN/albumin ratio at study cut-off

  n = 358

  Ata (2021) † | 66 vs 48 | 44 vs 39 | 358 | 0.823 | 74.5/75.6 | 3.4 | Mortality | Turkey

  PMID:36800572 · one of two readings recorded this

• sensitivity of BUN/albumin ratio at study cut-off

  n = 609

  Gemcioglu (2021) | 68 vs 46 | 56 vs 57 | 609 | 0.795 | 63.37/84.89 | 4.83 | Severity | Turkey

  PMID:36800572 · one of two readings recorded this

• sensitivity of BUN/albumin ratio at study cut-off

  n = 1370

  Huang (2021) | 67 vs 54 | 62 vs 44 | 1370 | 0.821 | 69/78.6 | 3.79 | Severity | China

  PMID:36800572 · one of two readings recorded this

• sensitivity of BUN/albumin ratio at study cut-off

  n = 602

  Kucukceran (2021) | 75 vs 60 | 66 vs 49 | 602 | 0.809 | 87.5/59.9 | 3.9 | Mortality | Turkey

  PMID:36800572 · one of two readings recorded this

• sensitivity of BUN/albumin ratio at study cut-off

  n = 131

  Singh (2022) | 56 vs 53 | 31 vs 69 | 131 | 0.695 | 79/54 | 6.23 | Mortality | India

  PMID:36800572 · one of two readings recorded this

• specificity of BUN/albumin ratio at study cut-off

  n = 433

  Alirezaei (2022) | 72 vs 56 | 63 vs 60 | 433 | 0.733 | 75.8/70.8 | 4.94 | Mortality | Iran

  PMID:36800572 · one of two readings recorded this

• specificity of BUN/albumin ratio at study cut-off

  n = 358

  Ata (2021) † | 66 vs 48 | 44 vs 39 | 358 | 0.823 | 74.5/75.6 | 3.4 | Mortality | Turkey

  PMID:36800572 · one of two readings recorded this

• specificity of BUN/albumin ratio at study cut-off

  n = 609

  Gemcioglu (2021) | 68 vs 46 | 56 vs 57 | 609 | 0.795 | 63.37/84.89 | 4.83 | Severity | Turkey

  PMID:36800572 · one of two readings recorded this

• specificity of BUN/albumin ratio at study cut-off

  n = 1370

  Huang (2021) | 67 vs 54 | 62 vs 44 | 1370 | 0.821 | 69/78.6 | 3.79 | Severity | China

  PMID:36800572 · one of two readings recorded this

• specificity of BUN/albumin ratio at study cut-off

  n = 602

  Kucukceran (2021) | 75 vs 60 | 66 vs 49 | 602 | 0.809 | 87.5/59.9 | 3.9 | Mortality | Turkey

  PMID:36800572 · one of two readings recorded this

• specificity of BUN/albumin ratio at study cut-off

  n = 131

  Singh (2022) | 56 vs 53 | 31 vs 69 | 131 | 0.695 | 79/54 | 6.23 | Mortality | India

  PMID:36800572 · one of two readings recorded this

• negative likelihood ratio

  a negative likelihood ratio (LR-) of 0.05 (95%CI: 0.04-0.06)

  PMID:38463019 · one of two readings recorded this

• negative likelihood ratio

  a negative likelihood ratio (LR-) of 0.06 (95%CI: 0.04-0.08)

  PMID:38463019 · one of two readings recorded this

• positive likelihood ratio

  a positive likelihood ratio (LR+) of 22.00 (95%CI: 15.60-30.10)

  PMID:38463019 · one of two readings recorded this

• positive likelihood ratio

  a positive likelihood ratio (LR+) of 10.10 (95%CI: 5.74-16.90)

  PMID:38463019 · one of two readings recorded this

• diagnostic odds ratio

  the DOR was calculated at 586.47 (95%CI: 340.03-1011.51)

  PMID:38463019 · one of two readings recorded this

• diagnostic odds ratio

  a DOR of 226.50 (95%CI: 102.57-500.15)

  PMID:38463019 · one of two readings recorded this

• Egger test intercept for publication bias

  p = 0.001

  The intercept was 2.54 with a P value < 0.001 for 13C-UBT and 3.04 with a P value < 0.001 for 14C-UBT

  PMID:38463019 · one of two readings recorded this

• Egger test intercept for publication bias

  p = 0.001

  The intercept was 2.54 with a P value < 0.001 for 13C-UBT and 3.04 with a P value < 0.001 for 14C-UBT

  PMID:38463019 · one of two readings recorded this

• pooled sensitivity for H. pylori infection

  In cases where 100 mg of urea was used (in 12 studies), the 13C-UBT demonstrated a sensitivity of 97.31% (95%CI: 95.92-98.70) and a specificity of 96.08% (95%CI: 94.34-97.82)

  PMID:38463019 · one of two readings recorded this

• pooled sensitivity for H. pylori infection

  Two studies employing 125 mg of urea showed a sensitivity of 93.76% (95%CI: 86.13-100.00) and a specificity of 88.66% (95%CI: 81.07-96.25)

  PMID:38463019 · one of two readings recorded this

• pooled sensitivity for H. pylori infection

  a 25 mg urea dose demonstrated notably high sensitivity (98.85%; 95%CI: 95.68-100.00) and specificity (99.13%; 95%CI: 96.73-100.00)

  PMID:38463019 · one of two readings recorded this

• pooled sensitivity for H. pylori infection

  in a single study using 250 mg of urea, the 13C-UBT exhibited a sensitivity of 97.06% (95%CI: 91.38-100.00) and a specificity of 98.59% (95%CI: 94.72-100.00)

  PMID:38463019 · one of two readings recorded this

• pooled sensitivity for H. pylori infection

  Increasing the urea dose to 50 mg across four studies resulted in a sensitivity of 95.28% (95%CI: 88.51-100.00) and a specificity of 94.91% (95%CI: 87.67-100.00)

  PMID:38463019 · one of two readings recorded this

• pooled sensitivity for H. pylori infection

  Seventeen studies explored the use of 75 mg of urea in the 13C-UBT, revealing a sensitivity of 96.47% (95%CI: 95.14-97.79) and a specificity of 98.33% (95%CI: 97.59-99.07)

  PMID:38463019 · one of two readings recorded this

• pooled sensitivity for H. pylori infection

  two studies using 0.75 µCi of urea reported a sensitivity of 88.94% (95%CI: 76.10-100.00) and a specificity of 91.32% (95%CI: 78.18-100.00)

  PMID:38463019 · one of two readings recorded this

• pooled sensitivity for H. pylori infection

  when employing 1 µCi of marked urea (in 14 studies), the 14C-UBT exhibited a sensitivity of 96.78% (95%CI: 95.46-98.09) and a specificity of 87.19% (95%CI: 59.76-95.81)

  PMID:38463019 · one of two readings recorded this

• pooled sensitivity for H. pylori infection

  Elevating the urea dose to 10 µCi, as explored in a single study, resulted in a sensitivity of 96.72% (95%CI: 92.15-100.00) and a specificity of 80.00% (95%CI: 56.76-100.00)

  PMID:38463019 · one of two readings recorded this

• pooled sensitivity for H. pylori infection

  the use of a 5 µCi marked urea dose, as examined in four studies, demonstrated exceptional sensitivity (99.21%; 95%CI: 98.20-100.00) and specificity (93.43%; 95%CI 86.45-100.00)

  PMID:38463019 · one of two readings recorded this

• pooled sensitivity for H. pylori infection

  p = 0.01

  sensitivity of 96.60% (95%CI: 95.64-97.56; P value < 0.01; I2 = 65.0%)

  PMID:38463019 · one of two readings recorded this

• pooled sensitivity for H. pylori infection

  p = 0.01

  sensitivity of 96.15% (95%CI: 94.47-97.82; P value < 0.01; I2 = 62.0%)

  PMID:38463019 · one of two readings recorded this

• pooled sensitivity for H. pylori infection

  yielded a sensitivity of 91.67% (95%CI: 84.67-98.66) and a specificity of 93.02% (95%CI: 85.41-100.00)

  PMID:38463019 · one of two readings recorded this

• pooled sensitivity for H. pylori infection

  ICOS demonstrated a sensitivity of 98.99% (95%CI: 96.20-100.00) and a specificity of 98.55% (95%CI: 94.56-100.00)

  PMID:38463019 · one of two readings recorded this

• pooled sensitivity for H. pylori infection

  Infrared spectrometry, assessed in 8 studies, displayed a sensitivity of 94.72% (95%CI: 90.91-98.54) and a specificity of 98.55% (95%CI: 88.17-98.22)

  PMID:38463019 · one of two readings recorded this

• pooled sensitivity for H. pylori infection

  Isotope-ratio mass spectrometry, scrutinized in 17 studies, demonstrated a sensitivity of 97.37% (95%CI: 96.45-98.28) and a specificity of 98.38% (95%CI: 84.67-98.66)

  PMID:38463019 · one of two readings recorded this

• pooled sensitivity for H. pylori infection

  recorded a sensitivity of 91.65% (95%CI: 88.31-94.78) and a specificity of 91.92% (95%CI: 88.61-98.21)

  PMID:38463019 · one of two readings recorded this

• pooled sensitivity for H. pylori infection

  exhibited a sensitivity of 97.83% (95%CI: 93.61-100.00) and a specificity of 96.08% (95%CI: 90.75-100.00)

  PMID:38463019 · one of two readings recorded this

• pooled sensitivity for H. pylori infection

  the use of Beta-scintillation counter for the assessment of 14C-UBT resulted in a sensitivity of 98.11% (95%CI: 95.33-100.00) and a specificity of 93.47% (95%CI: 88.11-98.82)

  PMID:38463019 · one of two readings recorded this

• pooled sensitivity for H. pylori infection

  the Heliprobe Analyser, assessed in 7 studies, displayed a sensitivity of 95.41% (95%CI: 93.32-97.50) and a specificity of 88.10% (95%CI: 74.43-100.00)

  PMID:38463019 · one of two readings recorded this

• pooled sensitivity for H. pylori infection

  liquid scintillation counting yielded a higher sensitivity of 98.79% (95%CI: 97.90-99.69) while maintaining a specificity of 87.24% (95%CI: 77.69-96.79)

  PMID:38463019 · one of two readings recorded this

• pooled sensitivity for H. pylori infection

  Solid Scintillation UBT (scintillation counting) demonstrated higher specificity, reaching 97.46% (95%CI: 94.62-100.00), with a sensitivity of 95.40% (95%CI: 91.00-99.80)

  PMID:38463019 · one of two readings recorded this

• pooled sensitivity for H. pylori infection

  Tests performed 10 min after urea administration (based on one study) yielded a sensitivity of 97.56% (95%CI: 90.88-100.0) and a specificity of 97.56% (95%CI: 90.88-100.00)

  PMID:38463019 · one of two readings recorded this

• pooled sensitivity for H. pylori infection

  tests carried out at 15 min post-urea administration (as reported in five studies), sensitivity averaged at 97.61% (95%CI: 95.68-99.55), with specificity at 95.85% (95%CI: 91.33-100.00)

  PMID:38463019 · one of two readings recorded this

• pooled sensitivity for H. pylori infection

  optimal sensitivity (98.87%; 95%CI: 98.14-99.60) and specificity (98.14%; 95%CI: 96.98-99.30) were achieved when the assessment was conducted 20 min after urea administration

  PMID:38463019 · one of two readings recorded this

• pooled sensitivity for H. pylori infection

  tests performed 30 min after urea administration (in 19 studies) had a sensitivity of 95.15% (95%CI: 93.30-96.92) and a specificity of 96.18% (95%CI: 94.48-97.87)

  PMID:38463019 · one of two readings recorded this

• pooled sensitivity for H. pylori infection

  For tests conducted 5 min post-urea administration (in one study), sensitivity was 97.83% (95%CI: 93.61-100.0), and specificity was 96.08% (95%CI: 90.75-100.00)

  PMID:38463019 · one of two readings recorded this

• pooled sensitivity for H. pylori infection

  A single study conducting tests 60 min post-urea administration reported a sensitivity of 96.03% (95%CI: 92.62-99.44) and a specificity of 97.83% (95%CI: 93.61-100.00)

  PMID:38463019 · one of two readings recorded this

• pooled sensitivity for H. pylori infection

  four studies investigating multiple time points after urea administration, the sensitivity was 96.13% (95%CI: 92.13-100.0), and the specificity was 97.95% (95%CI: 96.08-99.81)

  PMID:38463019 · one of two readings recorded this

• pooled sensitivity for H. pylori infection

  A single study, conducted at 12.5 minutes post-administration, reported a sensitivity of 96.05% (95%CI: 91.67-100.00) and a specificity of 95.12% (95%CI: 88.53-100.00)

  PMID:38463019 · one of two readings recorded this

• pooled sensitivity for H. pylori infection

  highest sensitivity (98.39%; 95%CI: 96.36-100.00) and specificity (98.71%; 95%CI: 96.58-100.00) when the tests were conducted 15 minutes after urea administration

  PMID:38463019 · one of two readings recorded this

• pooled sensitivity for H. pylori infection

  studies conducted at 20 min post-administration (n = 3) showed a sensitivity of 96.52% (95%CI: 93.50-97.55) and a specificity of 97.23% (95%CI: 94.48-99.97)

  PMID:38463019 · one of two readings recorded this

• pooled sensitivity for H. pylori infection

  A single study conducted at 25 min post-urea administration reported a sensitivity of 82.29% (95%CI: 76.89-87.69) and a specificity of 84.00% (95%CI: 75.70-92.30)

  PMID:38463019 · one of two readings recorded this

• pooled sensitivity for H. pylori infection

  A study conducted at 30 minutes post-administration yielded a sensitivity of 97.78% (95%CI: 91.69-100.00) and a specificity of 95.12% (95%CI: 88.53-100.00)

  PMID:38463019 · one of two readings recorded this

• pooled sensitivity for H. pylori infection

  the sensitivity was 96.03% (95%CI: 91.79-100.00), and the specificity was 91.02% (95%CI: 76.07-100.00)

  PMID:38463019 · one of two readings recorded this

• pooled sensitivity for H. pylori infection

  Studies conducted between 10- and 15-minutes post-urea administration (n = 3) showed a sensitivity of 94.92% (95%CI: 89.31-100.00) and a specificity of 96.00% (95%CI: 88.32-100.00)

  PMID:38463019 · one of two readings recorded this

• pooled sensitivity for H. pylori infection

  the sensitivity was consistently high at 97.83% (95%CI: 96.34-99.33), while specificity was somewhat lower at 79.90% (95%CI: 66.15-93.65)

  PMID:38463019 · one of two readings recorded this

• pooled specificity for H. pylori infection

  In cases where 100 mg of urea was used (in 12 studies), the 13C-UBT demonstrated a sensitivity of 97.31% (95%CI: 95.92-98.70) and a specificity of 96.08% (95%CI: 94.34-97.82)

  PMID:38463019 · one of two readings recorded this

• pooled specificity for H. pylori infection

  Two studies employing 125 mg of urea showed a sensitivity of 93.76% (95%CI: 86.13-100.00) and a specificity of 88.66% (95%CI: 81.07-96.25)

  PMID:38463019 · one of two readings recorded this

• pooled specificity for H. pylori infection

  a 25 mg urea dose demonstrated notably high sensitivity (98.85%; 95%CI: 95.68-100.00) and specificity (99.13%; 95%CI: 96.73-100.00)

  PMID:38463019 · one of two readings recorded this

• pooled specificity for H. pylori infection

  in a single study using 250 mg of urea, the 13C-UBT exhibited a sensitivity of 97.06% (95%CI: 91.38-100.00) and a specificity of 98.59% (95%CI: 94.72-100.00)

  PMID:38463019 · one of two readings recorded this

• pooled specificity for H. pylori infection

  Increasing the urea dose to 50 mg across four studies resulted in a sensitivity of 95.28% (95%CI: 88.51-100.00) and a specificity of 94.91% (95%CI: 87.67-100.00)

  PMID:38463019 · one of two readings recorded this

• pooled specificity for H. pylori infection

  Seventeen studies explored the use of 75 mg of urea in the 13C-UBT, revealing a sensitivity of 96.47% (95%CI: 95.14-97.79) and a specificity of 98.33% (95%CI: 97.59-99.07)

  PMID:38463019 · one of two readings recorded this

• pooled specificity for H. pylori infection

  two studies using 0.75 µCi of urea reported a sensitivity of 88.94% (95%CI: 76.10-100.00) and a specificity of 91.32% (95%CI: 78.18-100.00)

  PMID:38463019 · one of two readings recorded this

• pooled specificity for H. pylori infection

  when employing 1 µCi of marked urea (in 14 studies), the 14C-UBT exhibited a sensitivity of 96.78% (95%CI: 95.46-98.09) and a specificity of 87.19% (95%CI: 59.76-95.81)

  PMID:38463019 · one of two readings recorded this

• pooled specificity for H. pylori infection

  Elevating the urea dose to 10 µCi, as explored in a single study, resulted in a sensitivity of 96.72% (95%CI: 92.15-100.00) and a specificity of 80.00% (95%CI: 56.76-100.00)

  PMID:38463019 · one of two readings recorded this

• pooled specificity for H. pylori infection

  the use of a 5 µCi marked urea dose, as examined in four studies, demonstrated exceptional sensitivity (99.21%; 95%CI: 98.20-100.00) and specificity (93.43%; 95%CI 86.45-100.00)

  PMID:38463019 · one of two readings recorded this

• pooled specificity for H. pylori infection

  p = 0.01

  specificity of 96.93% (95%CI: 96.04-97.82; P value < 0.01; I2 = 58.0%)

  PMID:38463019 · one of two readings recorded this

The whole record — 804 rows