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Proteins/UNIPROT:Q8NE62
Catalyzes the dehydrogenation of choline to betaine aldehyde in the mitochondria (By similarity). Involved in mitochondrial autophagy after mitochondrial damage..
Function from UniProtKB (Q8NE62), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 1 · substrate of
1 compound
1 compound.
0 reported routes1 assembled route
33 statements
33 statements · 7 reference databases · Subject: CHDH · Sources: Hetionet, Human Protein Atlas, Human-GEM, Reactome, Rhea, UniProt, WikiPathways
4 reactions
choline+NAD(+)betaine aldehyde+proton+NADH(2-)
Catalysed by CHDH
Reaction pageLeft to rightBalancedEC 1.1.99.1cytosol
Human-GEM MAR04696CC BY 4.0Reference data
2 names
Resolves to: CHDH
Reaction pageReversibleBalancedEC 1.5.5.1mitochondrial matrix
Human-GEM MAR06911CC BY 4.0Reference data
choline+FADbetaine aldehyde+FADH2
Catalysed by CHDH
Reaction pageLeft to rightBalancedEC 1.1.99.1mitochondrial matrix
Human-GEM MAR08441CC BY 4.0Reference data
Catalysed by CHDH
Reaction pageLeft to rightBalanced
Rhea RHEA:17433CC BY 4.0Reference data