Compound
kinetensin
A peptide cation obtained from the deprotonation of the carboxy group of L-leucine residue, and protonation of the amino group of L-isoleucyl and protonation of the side chains of L-arginyl residues of kinetensin. It is the major species at pH 7.3.
Definition from ChEBI (CHEBI:147364), read 2026-09-23. CC BY 4.0.
Structure
No depiction stored
No three-dimensional record for this entry.
- Class
- Organic compound, cation
- Formula
- C56H87N17O11
- Mass
- 1174.42 g/mol
- Charge
- +2
- InChIKey
- PANUJGMSOSQAAY-IHXGQVBNSA-P
- SMILES
- CC[C@H](C)[C@H]([NH3+])C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=[NH2+])C(=O)N[C@@H](CCCNC(N)=[NH2+])C(=O)N[C@@H](Cc1cncn1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)[O-]
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
4 entities
4 entities reached.
0 reported hops4 assembled from the scaffold
- ACE2ProteinUNIPROT:Q9BYF1substrate ofInferred only37 paths37 endpoints
- CMA1ProteinUNIPROT:P23946substrate ofInferred only12 paths6 endpoints
- CPA1ProteinUNIPROT:P15085substrate ofInferred only8 paths4 endpoints
- L-leucineCompoundCHEBI:15603converted toInferred only2 paths1 endpoint
What the reference databases state
Statements
18 statements
18 statements · 2 reference databases · Subject: kinetensin · Sources: Human-GEM, Rhea
- kinetensin is converted to L-leucineCompoundHuman-GEM MAR03043Inferred only
- L-leucine is converted to kinetensinCompoundHuman-GEM MAR03043Inferred only
- kinetensin is converted to L-leucineCompoundHuman-GEM MAR09482Inferred only
- kinetensin is a substrate of ACE2ProteinRhea RHEA:63544Inferred only
- kinetensin is a substrate of CMA1ProteinHuman-GEM MAR03042Inferred only
- kinetensin is a substrate of CMA1ProteinHuman-GEM MAR09481Inferred only
- kinetensin is a substrate of CPA1ProteinHuman-GEM MAR09482Inferred only
- kinetensin is a substrate of CPA1ProteinHuman-GEM MAR03043Inferred only
- kinetensin is a substrate of CPA2ProteinHuman-GEM MAR09482Inferred only
- kinetensin is a substrate of CPA2ProteinHuman-GEM MAR03043Inferred only
- kinetensin is a substrate of CPA3ProteinHuman-GEM MAR09482Inferred only
- kinetensin is a substrate of CPA5ProteinHuman-GEM MAR03043Inferred only
Show the remaining 6
- kinetensin is a substrate of CPA5ProteinHuman-GEM MAR09482Inferred only
- kinetensin is a substrate of CPA6ProteinHuman-GEM MAR03043Inferred only
- kinetensin is a substrate of CPA6ProteinHuman-GEM MAR09482Inferred only
- kinetensin is a substrate of TPSAB1ProteinHuman-GEM MAR09483Inferred only
- kinetensin is a substrate of TPSB2ProteinHuman-GEM MAR09483Inferred only
- kinetensin is a substrate of TPSD1ProteinHuman-GEM MAR09483Inferred only
Reactions
7 reactions
2water+kinetensinMAM02315e+L-leucine+L-phenylalanine
Catalysed by CMA1
Reaction pageReversibleBalancedEC 3.4.21.39GO:0005615
Human-GEM MAR03042CC BY 4.0Reference data
water+kinetensinMAM02316e+L-leucine
Catalysed by CPA1 or CPA2 or CPA5 or CPA6
Reaction pageReversibleBalancedEC 3.4.17.1GO:0005615
Human-GEM MAR03043CC BY 4.0Reference data
Reaction pageReversibleBalance undeterminableGO:0005615
Human-GEM MAR04341CC BY 4.0Reference data
2water+kinetensinMAM02315c+L-leucine+L-phenylalanine
Catalysed by CMA1
Reaction pageLeft to rightBalancedEC 3.4.21.39GO:0005829
Human-GEM MAR09481CC BY 4.0Reference data
water+kinetensinMAM02316c+L-leucine
Catalysed by CPA1 or CPA2 or CPA5 or CPA3 or CPA6
Reaction pageLeft to rightBalancedEC 3.4.17.1, 3.4.17.15GO:0005829
Human-GEM MAR09482CC BY 4.0Reference data
2water+kinetensinMAM02314e+MAM02317e+L-leucine
Catalysed by TPSD1 or TPSAB1 or TPSB2
Reaction pageLeft to rightBalancedEC 3.4.21.59GO:0005615
Human-GEM MAR09483CC BY 4.0Reference data
kinetensin+waterkinetensin-(1-8)+L-leucine
Catalysed by ACE2
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:63544CC BY 4.0Reference data
Other names
4 names
Resolves to: kinetensin
- Also called
- Ile-Ala-Arg-Arg-His-Pro-Tyr-Phe-Leu(2+)L-isoleucyl-L-alanyl-L-arginyl-L-arginyl-L-histidyl-L-prolyl-L-tyrosyl-L-phenylalanyl-L-leucine(2+)
- Systematic name
- N-[(2S,3S)-2-azaniumyl-3-methylpentanoyl]-L-alanyl-N(5)-[amino(iminio)methyl]-L-ornithyl-N(5)-[amino(iminio)methyl]-L-ornithyl-L-histidyl-L-prolyl-L-tyrosyl-N-[(1S)-1-carboxylato-3-methylbutyl]-L-phenylalaninamideN-[(2S,3S)-2-azaniumyl-3-methylpentanoyl]-L-alanyl-N5-[amino(iminio)methyl]-L-ornithyl-N5-[amino(iminio)methyl]-L-ornithyl-L-histidyl-L-prolyl-L-tyrosyl-N-[(1S)-1-carboxylato-3-methylbutyl]-L-phenylalaninamide