2-oxobutanoate

1. 2-hydroxybutyrate:NAD+ oxidoreductase

Catalysed by LDHB, LDHC, LDHAL6A, LDHAL6Bcytosol

1. 2-oxobutanoate + L-alanine = (2S)-2-aminobutanoate + pyruvate

Catalysed by AGXT2

1. 2-oxobutyrate oxidation

No catalyst recordedcytosol

1. branched chain keto acid dehydrogenase E1 (2-oxobutyrate)

Catalysed by BCKDHA, BCKDHBmitochondrial matrix

1. N(omega),N(omega)-dimethyl-L-arginine + 2-oxobutanoate = 5-(3,3-dimethylguanidino)-2-oxopentanoate + (2S)-2-aminobutanoate

Catalysed by AGXT2

1. Selenomethionine methanethiol-lyase (deaminating)

Catalysed by CTHcytosol

1. Selenocystathionine Lysteine-lyase (deaminating)

Catalysed by CTHcytosol

1. glutamic-pyruvic transaminase ((S)-2-aminobutanoate)

Catalysed by GPTcytosol

1. (2S)-2-aminobutanoate + glyoxylate = 2-oxobutanoate + glycine

Catalysed by AGXT2

1. L-threonine = 2-oxobutanoate + NH4(+)

Catalysed by SDS, SDSL

1. 2-oxobutanoate + L-kynurenine = (2S)-2-aminobutanoate + kynurenate + H2O

Catalysed by AADAT

1. 2-oxobutanoate + L-kynurenine = (2S)-2-aminobutanoate + kynurenate + H2O

Catalysed by AADATOne of 5 routes

1. 2-iminobutanoate + H2O = 2-oxobutanoate + NH4(+)

Catalysed by RIDA

1. 2-oxobutyrate oxidation
2. Active Transport

No catalyst recordedcytosol, mitochondrial matrixOne of 2 routes

1. 2-oxobutyrate oxidation
2. Propanoyl-CoA hydrolase

Catalysed by ACOT7cytosolOne of 13 routes

1. 2-hydroxybutyrate:NAD+ oxidoreductase