succinic semialdehyde

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

60 compounds within 3 steps: 2 in 1, 6 in 2, 52 in 3

One step

4-hydroxybutanoateReach from here →
1. Formation of 4-Hydroxy-Butyrate
No catalyst recordedmitochondrial matrix
4-aminobutanoateReach from here →
1. 4-aminobutanoate:2-oxoglutarate aminotransferase
Catalysed by ABATmitochondrial matrix

Two steps

L-homocarnosineReach from here →
1. 4-aminobutanoate:2-oxoglutarate aminotransferase
2. Formation of homocarnosine
Catalysed by ABAT, CARNS1mitochondrial matrix, cytosolOne of 2 routes
(R)-2-hydroxyglutarateReach from here →
1. Formation of 4-Hydroxy-Butyrate
2. 4-hydroxybutanoate + 2-oxoglutarate = (R)-2-hydroxyglutarate + succinate semialdehyde
Catalysed by ADHFE1mitochondrial matrix
chlorine(.)Reach from here →

Three steps

4-aminobutanoate:2-oxoglutarate aminotransferase

transport of 4-aminobutyrate and chloride (cytosol to extracellular)

Catalysed by ABAT, SLC6A12mitochondrial matrix, extracellular space, cytosolOne of 4 routes

L-ornithineReach from here →

Catalysed by ABAT, GATMmitochondrial matrix

4-guanidinobutanoateReach from here →

Catalysed by ABAT, GATMmitochondrial matrix

succinate semialdehydeReach from here →

Catalysed by ABATmitochondrial matrixOne of 3 routes

mitochondrial matrix, extracellular space, cytosol

D-histidineReach from here →

Catalysed by ABAT, GATM, SLC25A2mitochondrial matrix, inner side of the membrane, outer side of the membraneOne of 2 routes

L-homoarginineReach from here →

Catalysed by ABAT, GATM, SLC25A2mitochondrial matrix, inner side of the membrane, outer side of the membraneOne of 2 routes

cholineReach from here →

Catalysed by ABAT, SLC6A12, SLC5A7mitochondrial matrix, extracellular space, cytosol

L-leucineReach from here →

Catalysed by ABAT, SLC6A12, SLC6A14mitochondrial matrix, extracellular space, cytosolOne of 6 routes

CHEBI:15699Reach from here →

Catalysed by ABAT, GATM, SLC7A6mitochondrial matrix, extracellular space, cytosolOne of 2 routes

CHEBI:15971Reach from here →

Catalysed by ABAT, CARNS1, CNDP1, CNDP2mitochondrial matrix, cytosolOne of 6 routes

sulfateReach from here →

Catalysed by ABAT, SLC6A12, SLC26A6mitochondrial matrix, extracellular space, cytosol

ureaReach from here →

Catalysed by ABAT, GATM, AGMATmitochondrial matrix

L-citrullineReach from here →

Catalysed by ABAT, GATM, SLC7A9mitochondrial matrix, extracellular space, cytosolOne of 9 routes

iodideReach from here →

Catalysed by ABAT, SLC6A12, SLC26A4mitochondrial matrix, extracellular space, cytosol

L-valineReach from here →

Catalysed by ABAT, SLC6A12, SLC6A14mitochondrial matrix, extracellular space, cytosolOne of 4 routes

L-arginineReach from here →

Catalysed by ABAT, SLC6A12, SLC6A14mitochondrial matrix, extracellular space, cytosolOne of 9 routes

N(2)-acetyl-L-ornithineReach from here →

Catalysed by ABAT, GATM, ACY1mitochondrial matrix, cytosol

CHEBI:16857Reach from here →

Catalysed by ABAT, SLC6A12, SLC6A14mitochondrial matrix, extracellular space, cytosolOne of 3 routes

oxalic acidReach from here →

Catalysed by ABAT, SLC6A12, SLC26A6mitochondrial matrix, extracellular space, cytosol

L-isoleucineReach from here →

Catalysed by ABAT, SLC6A12, SLC6A14mitochondrial matrix, extracellular space, cytosolOne of 4 routes

CHEBI:17203Reach from here →

Catalysed by ABAT, SLC6A12, CLTRN, SLC6A20mitochondrial matrix, extracellular space, cytosolOne of 4 routes

L-glutamic 5-semialdehydeReach from here →

Catalysed by ABAT, GATM, OATmitochondrial matrix

AH2Reach from here →

Catalysed by ADHFE1, D2HGDHmitochondrial matrix

L-cysteineReach from here →

Catalysed by ABAT, SLC6A12, SLC6A14mitochondrial matrix, extracellular space, cytosolOne of 4 routes

glycine betaineReach from here →

Catalysed by ABAT, SLC6A12mitochondrial matrix, extracellular space, cytosolOne of 3 routes

CHEBI:17895Reach from here →

Catalysed by ABAT, SLC6A12, SLC6A14mitochondrial matrix, extracellular space, cytosolOne of 4 routes

CHEBI:18019Reach from here →

Catalysed by ABAT, SLC6A12, SLC6A14mitochondrial matrix, extracellular space, cytosolOne of 5 routes

L-glutamineReach from here →

Catalysed by ABAT, SLC6A12, SLC6A14mitochondrial matrix, extracellular space, cytosolOne of 3 routes

CHEBI:18095Reach from here →

Catalysed by ABAT, SLC6A12, CLTRN, SLC6A20mitochondrial matrix, extracellular space, cytosol

N-carbamoyl-beta-alanineReach from here →

Catalysed by ABAT, SLC6A12mitochondrial matrix, extracellular space, cytosolOne of 2 routes

CHEBI:240943Reach from here →

Catalysed by ABAT, SLC6A12, SLC6A5mitochondrial matrix, extracellular space, cytosolOne of 2 routes

hypochlorous acidReach from here →

Catalysed by ABAT, SLC6A12, LPOmitochondrial matrix, extracellular space, cytosolOne of 4 routes

potassium atomReach from here →

Catalysed by ABAT, SLC6A12, SLC12A2, SLC12A1mitochondrial matrix, extracellular space, cytosolOne of 2 routes

Ca(2+)Reach from here →

Catalysed by ABAT, CARNS1mitochondrial matrix, cytosol, extracellular spaceOne of 2 routes

formic acidReach from here →

Catalysed by ABAT, SLC6A12, SLC26A4mitochondrial matrix, extracellular space, cytosolOne of 2 routes

malonic acidReach from here →

Catalysed by ABAT, SLC6A12mitochondrial matrix, extracellular space, cytosolOne of 2 routes

L-lysineReach from here →

Catalysed by ABAT, GATM, SLC25A2, SLC25A15mitochondrial matrix, inner side of the membrane, outer side of the membraneOne of 2 routes

D-lysineReach from here →

Catalysed by ABAT, GATM, SLC25A2mitochondrial matrix, inner side of the membrane, outer side of the membraneOne of 2 routes

putrescineReach from here →

Catalysed by ABAT, GATM, ODC1mitochondrial matrix, cytosolOne of 3 routes

D-arginineReach from here →

Catalysed by ABAT, GATM, SLC25A2mitochondrial matrix, inner side of the membrane, outer side of the membraneOne of 2 routes

taurineReach from here →

Catalysed by ABAT, SLC6A12, SLC6A6mitochondrial matrix, extracellular space, cytosolOne of 2 routes

glycineReach from here →

Catalysed by ABAT, SLC6A12, SLC6A9, SLC6A14mitochondrial matrix, extracellular space, cytosolOne of 7 routes

L-histidineReach from here →

Catalysed by ABAT, CARNS1, CNDP1mitochondrial matrix, cytosolOne of 3 routes

D-ornithineReach from here →

Catalysed by ABAT, GATM, SLC25A2mitochondrial matrix, inner side of the membrane, outer side of the membraneOne of 2 routes