Compound
CHEBI:16284
A purine 2'-deoxyribonucleoside 5'-triphosphate having adenine as the nucleobase.
Definition from ChEBI (CHEBI:16284), read 2026-09-23. CC BY 4.0.
What it touches on the way
Mechanistic reach
36 entities
36 entities reached.
0 reported hops36 assembled from the scaffold
- NME1ProteinUNIPROT:P15531substrate ofInferred only162 paths27 endpoints
- NME2ProteinUNIPROT:P22392substrate ofInferred only146 paths26 endpoints
- HK1ProteinUNIPROT:P19367substrate ofInferred only132 paths33 endpoints
- HK2ProteinUNIPROT:P52789substrate ofInferred only100 paths25 endpoints
- RFC5ProteinUNIPROT:P40937substrate ofInferred only87 paths87 endpoints
- POLD2ProteinUNIPROT:P49005substrate ofInferred only73 paths73 endpoints
- POLD1ProteinUNIPROT:P28340substrate ofInferred only68 paths68 endpoints
- HK3ProteinUNIPROT:P52790substrate ofInferred only66 paths22 endpoints
- POLD3ProteinUNIPROT:Q15054substrate ofInferred only60 paths60 endpoints
- POLEProteinUNIPROT:Q07864substrate ofInferred only52 paths52 endpoints
- POLA1ProteinUNIPROT:P09884substrate ofInferred only49 paths49 endpoints
- POLD4ProteinUNIPROT:Q9HCU8substrate ofInferred only49 paths49 endpoints
Show the remaining 24
- NME7ProteinUNIPROT:Q9Y5B8substrate ofInferred only48 paths12 endpoints
- POLE2ProteinUNIPROT:P56282substrate ofInferred only45 paths45 endpoints
- POLA2ProteinUNIPROT:Q14181substrate ofInferred only44 paths44 endpoints
- NME3ProteinUNIPROT:Q13232substrate ofInferred only40 paths8 endpoints
- POLE4ProteinUNIPROT:Q9NR33substrate ofInferred only39 paths39 endpoints
- POLE3ProteinUNIPROT:Q9NRF9substrate ofInferred only38 paths38 endpoints
- POLBProteinUNIPROT:P06746substrate ofInferred only31 paths31 endpoints
- POLKProteinUNIPROT:Q9UBT6substrate ofInferred only31 paths31 endpoints
- NME4ProteinUNIPROT:O00746substrate ofInferred only30 paths6 endpoints
- NME6ProteinUNIPROT:O75414substrate ofInferred only30 paths6 endpoints
- POLHProteinUNIPROT:Q9Y253substrate ofInferred only27 paths27 endpoints
- REV3LProteinUNIPROT:O60673substrate ofInferred only20 paths20 endpoints
- HKDC1ProteinUNIPROT:Q2TB90substrate ofInferred only20 paths5 endpoints
- DTYMKProteinUNIPROT:P23919substrate ofInferred only18 paths9 endpoints
- POLIProteinUNIPROT:Q9UNA4substrate ofInferred only16 paths16 endpoints
- CMPK1ProteinUNIPROT:P30085substrate ofInferred only12 paths2 endpoints
- POLGProteinUNIPROT:P54098substrate ofInferred only9 paths9 endpoints
- POLLProteinUNIPROT:Q9UGP5substrate ofInferred only8 paths8 endpoints
- AK5ProteinUNIPROT:Q9Y6K8substrate ofInferred only8 paths8 endpoints
- TENT4AProteinUNIPROT:Q5XG87substrate ofInferred only7 paths7 endpoints
- POLG2ProteinUNIPROT:Q9UHN1substrate ofInferred only6 paths6 endpoints
- POLMProteinUNIPROT:Q9NP87substrate ofInferred only5 paths5 endpoints
- POLNProteinUNIPROT:Q7Z5Q5substrate ofInferred only4 paths4 endpoints
- POLQProteinUNIPROT:O75417substrate ofInferred only4 paths4 endpoints
What the reference databases state
Statements
93 statements
93 statements · 1 reference database · Subject: CHEBI:16284 · Sources: Human-GEM
- CHEBI:16284 is converted to CHEBI:16174CompoundHuman-GEM MAR08470Inferred only
- CHEBI:16284 is converted to CHEBI:16174CompoundHuman-GEM MAR04044Inferred only
- CHEBI:16174 is converted to CHEBI:16284CompoundHuman-GEM MAR04044Inferred only
- CHEBI:16174 is converted to CHEBI:16284CompoundHuman-GEM MAR07869Inferred only
- CHEBI:16174 is converted to CHEBI:16284CompoundHuman-GEM MAR07870Inferred only
- CHEBI:16174 is converted to CHEBI:16284CompoundHuman-GEM MAR07892Inferred only
- CHEBI:16174 is converted to CHEBI:16284CompoundHuman-GEM MAR08469Inferred only
- CHEBI:16284 is converted to CHEBI:16174CompoundHuman-GEM MAR07870Inferred only
- CHEBI:16174 is converted to CHEBI:16284CompoundHuman-GEM MAR08470Inferred only
- CHEBI:16284 is converted to CHEBI:16174CompoundHuman-GEM MAR07869Inferred only
- CHEBI:16284 is converted to CHEBI:16174CompoundHuman-GEM MAR07892Inferred only
- CHEBI:16284 is converted to CHEBI:16174CompoundHuman-GEM MAR08469Inferred only
Show the remaining 81
- CHEBI:16284 is converted to CHEBI:16174CompoundHuman-GEM MAR04420Inferred only
- CHEBI:16284 is a substrate of AK5ProteinHuman-GEM MAR07802Inferred only
- CHEBI:16284 is a substrate of CMPK1ProteinHuman-GEM MAR08455Inferred only
- CHEBI:16284 is a substrate of CMPK1ProteinHuman-GEM MAR08469Inferred only
- CHEBI:16284 is a substrate of CMPK1ProteinHuman-GEM MAR08470Inferred only
- CHEBI:16284 is a substrate of CMPK1ProteinHuman-GEM MAR07869Inferred only
- CHEBI:16284 is a substrate of CMPK1ProteinHuman-GEM MAR08454Inferred only
- CHEBI:16284 is a substrate of CMPK1ProteinHuman-GEM MAR07870Inferred only
- CHEBI:16284 is a substrate of DTYMKProteinHuman-GEM MAR06612Inferred only
- CHEBI:16284 is a substrate of DTYMKProteinHuman-GEM MAR06613Inferred only
- CHEBI:16284 is a substrate of HK1ProteinHuman-GEM MAR04487Inferred only
- CHEBI:16284 is a substrate of HK1ProteinHuman-GEM MAR04493Inferred only
- CHEBI:16284 is a substrate of HK1ProteinHuman-GEM MAR04489Inferred only
- CHEBI:16284 is a substrate of HK1ProteinHuman-GEM MAR04496Inferred only
- CHEBI:16284 is a substrate of HK2ProteinHuman-GEM MAR04489Inferred only
- CHEBI:16284 is a substrate of HK2ProteinHuman-GEM MAR04496Inferred only
- CHEBI:16284 is a substrate of HK2ProteinHuman-GEM MAR04493Inferred only
- CHEBI:16284 is a substrate of HK2ProteinHuman-GEM MAR04487Inferred only
- CHEBI:16284 is a substrate of HK3ProteinHuman-GEM MAR04487Inferred only
- CHEBI:16284 is a substrate of HK3ProteinHuman-GEM MAR04489Inferred only
- CHEBI:16284 is a substrate of HK3ProteinHuman-GEM MAR04493Inferred only
- CHEBI:16284 is a substrate of HKDC1ProteinHuman-GEM MAR04487Inferred only
- CHEBI:16284 is a substrate of HKDC1ProteinHuman-GEM MAR04489Inferred only
- CHEBI:16284 is a substrate of HKDC1ProteinHuman-GEM MAR04496Inferred only
- CHEBI:16284 is a substrate of HKDC1ProteinHuman-GEM MAR04493Inferred only
- CHEBI:16284 is a substrate of NME1ProteinHuman-GEM MAR07892Inferred only
- CHEBI:16284 is a substrate of NME1ProteinHuman-GEM MAR04044Inferred only
- CHEBI:16284 is a substrate of NME1ProteinHuman-GEM MAR04420Inferred only
- CHEBI:16284 is a substrate of NME1ProteinHuman-GEM MAR06614Inferred only
- CHEBI:16284 is a substrate of NME1ProteinHuman-GEM MAR06615Inferred only
- CHEBI:16284 is a substrate of NME1ProteinHuman-GEM MAR06616Inferred only
- CHEBI:16284 is a substrate of NME2ProteinHuman-GEM MAR07892Inferred only
- CHEBI:16284 is a substrate of NME2ProteinHuman-GEM MAR06615Inferred only
- CHEBI:16284 is a substrate of NME2ProteinHuman-GEM MAR06616Inferred only
- CHEBI:16284 is a substrate of NME2ProteinHuman-GEM MAR06614Inferred only
- CHEBI:16284 is a substrate of NME2ProteinHuman-GEM MAR04044Inferred only
- CHEBI:16284 is a substrate of NME2ProteinHuman-GEM MAR04420Inferred only
- CHEBI:16284 is a substrate of NME3ProteinHuman-GEM MAR06615Inferred only
- CHEBI:16284 is a substrate of NME3ProteinHuman-GEM MAR06616Inferred only
- CHEBI:16284 is a substrate of NME3ProteinHuman-GEM MAR06614Inferred only
- CHEBI:16284 is a substrate of NME3ProteinHuman-GEM MAR04420Inferred only
- CHEBI:16284 is a substrate of NME3ProteinHuman-GEM MAR04044Inferred only
- CHEBI:16284 is a substrate of NME4ProteinHuman-GEM MAR06614Inferred only
- CHEBI:16284 is a substrate of NME4ProteinHuman-GEM MAR04420Inferred only
- CHEBI:16284 is a substrate of NME4ProteinHuman-GEM MAR06615Inferred only
- CHEBI:16284 is a substrate of NME4ProteinHuman-GEM MAR06616Inferred only
- CHEBI:16284 is a substrate of NME4ProteinHuman-GEM MAR04044Inferred only
- CHEBI:16284 is a substrate of NME6ProteinHuman-GEM MAR04044Inferred only
- CHEBI:16284 is a substrate of NME6ProteinHuman-GEM MAR06614Inferred only
- CHEBI:16284 is a substrate of NME6ProteinHuman-GEM MAR04420Inferred only
- CHEBI:16284 is a substrate of NME6ProteinHuman-GEM MAR06616Inferred only
- CHEBI:16284 is a substrate of NME6ProteinHuman-GEM MAR06615Inferred only
- CHEBI:16284 is a substrate of NME7ProteinHuman-GEM MAR06615Inferred only
- CHEBI:16284 is a substrate of NME7ProteinHuman-GEM MAR06616Inferred only
- CHEBI:16284 is a substrate of NME7ProteinHuman-GEM MAR04420Inferred only
- CHEBI:16284 is a substrate of NME7ProteinHuman-GEM MAR06614Inferred only
- CHEBI:16284 is a substrate of POLA1ProteinHuman-GEM MAR07160Inferred only
- CHEBI:16284 is a substrate of POLA2ProteinHuman-GEM MAR07160Inferred only
- CHEBI:16284 is a substrate of POLBProteinHuman-GEM MAR07160Inferred only
- CHEBI:16284 is a substrate of POLD1ProteinHuman-GEM MAR07160Inferred only
- CHEBI:16284 is a substrate of POLD2ProteinHuman-GEM MAR07160Inferred only
- CHEBI:16284 is a substrate of POLD3ProteinHuman-GEM MAR07160Inferred only
- CHEBI:16284 is a substrate of POLD4ProteinHuman-GEM MAR07160Inferred only
- CHEBI:16284 is a substrate of POLEProteinHuman-GEM MAR07160Inferred only
- CHEBI:16284 is a substrate of POLE2ProteinHuman-GEM MAR07160Inferred only
- CHEBI:16284 is a substrate of POLE3ProteinHuman-GEM MAR07160Inferred only
- CHEBI:16284 is a substrate of POLE4ProteinHuman-GEM MAR07160Inferred only
- CHEBI:16284 is a substrate of POLGProteinHuman-GEM MAR07160Inferred only
- CHEBI:16284 is a substrate of POLG2ProteinHuman-GEM MAR07160Inferred only
- CHEBI:16284 is a substrate of POLHProteinHuman-GEM MAR07160Inferred only
- CHEBI:16284 is a substrate of POLIProteinHuman-GEM MAR07160Inferred only
- CHEBI:16284 is a substrate of POLKProteinHuman-GEM MAR07160Inferred only
- CHEBI:16284 is a substrate of POLLProteinHuman-GEM MAR07160Inferred only
- CHEBI:16284 is a substrate of POLMProteinHuman-GEM MAR07160Inferred only
- CHEBI:16284 is a substrate of POLNProteinHuman-GEM MAR07160Inferred only
- CHEBI:16284 is a substrate of POLQProteinHuman-GEM MAR07160Inferred only
- CHEBI:16284 is a substrate of REV3LProteinHuman-GEM MAR07160Inferred only
- CHEBI:16284 is a substrate of RFC5ProteinHuman-GEM MAR07160Inferred only
- CHEBI:16284 is a substrate of TENT4AProteinHuman-GEM MAR07160Inferred only
- CHEBI:16284 is transported by SLC25A19ProteinHuman-GEM MAR20183Inferred only
- CHEBI:16284 is transported by SLC25A19ProteinHuman-GEM MAR20182Inferred only
Reactions
28 reactions
ADP+CHEBI:16284ATP+CHEBI:16174
Catalysed by NME3 or NME4 or NME6 or NME1 or NME2
Reaction pageReversibleBalancedEC 2.7.4.6cytosol
Human-GEM MAR04044CC BY 4.0Reference data
0.505626L-alanine+0.35926L-arginine+0.279425L-asparagine+0.352607L-aspartate+20.704451ATP+0.020401CHEBI:1307929+0.011658a cardiolipin+0.039036CHEBI:17677+0.046571L-cysteine+0.013183CHEBI:16284+0.009442dCTP+0.009898CHEBI:16497+0.013091dTTP+0.275194D-glucopyranose 6-phosphate+0.385872L-glutamate(1-)+0.325996L-glutamine+0.538891glycine+0.036117GTP+20.650823water+0.126406CHEBI:15971+0.286078L-isoleucine+0.545544L-leucine+0.592114CHEBI:18019+0.153018L-methionine+0.1544631,2-diacyl-sn-glycero-3-phosphocholine(1+)+0.055374phosphatidylethanolamine+0.002914MAM02715c+0.259466L-phenylalanine+0.0233151-phosphatidyl-1D-myo-inositol+0.412484CHEBI:17203+0.005829phosphatidyl-L-serine+0.392525L-seryl residue+0.017486a sphingomyelin+0.31269CHEBI:16857+0.013306L-tryptophan+0.159671CHEBI:17895+0.053446UTP+0.352607L-valine20.650823ADP+20.650823proton+20.650823phosphate(3-)+MAM03970c
Reaction pageBlockedBalance undeterminablecytosol, nucleus
Human-GEM MAR04413CC BY 4.0Reference data
ADP+CHEBI:16284ATP+CHEBI:16174
Catalysed by NME3 or NME4 or NME7 or NME6 or NME1 or NME2
Reaction pageLeft to rightBalancedEC 2.7.4.6mitochondrial matrix
Human-GEM MAR04420CC BY 4.0Reference data
CHEBI:16174+proton+phosphoenolpyruvic acidCHEBI:16284+pyruvate
Reaction pageLeft to rightBalancedEC 2.7.1.40cytosol
Human-GEM MAR04421CC BY 4.0Reference data
CHEBI:16284+D-glucoseCHEBI:16174+D-glucopyranose 6-phosphate+proton
Catalysed by HKDC1 or HK1 or HK2 or HK3
Reaction pageLeft to rightBalancedEC 2.7.1.1cytosol
Human-GEM MAR04487CC BY 4.0Reference data
CHEBI:16284+beta-D-fructoseCHEBI:16174+keto-D-fructose 6-phosphate+proton
Catalysed by HKDC1 or HK1 or HK2 or HK3
Reaction pageLeft to rightBalancedEC 2.7.1.1cytosol
Human-GEM MAR04489CC BY 4.0Reference data
CHEBI:16284+D-mannoseCHEBI:16174+proton+MAM02455c
Catalysed by HKDC1 or HK1 or HK2 or HK3
Reaction pageLeft to rightBalancedEC 2.7.1.1cytosol
Human-GEM MAR04493CC BY 4.0Reference data
CHEBI:16284+glucosamineCHEBI:16174+alpha-D-glucosamine 6-phosphate+proton
Catalysed by HKDC1 or HK1 or HK2
Reaction pageLeft to rightBalancedEC 2.7.1.1cytosol
Human-GEM MAR04496CC BY 4.0Reference data
ATP+thioredoxin dithiolCHEBI:16284+water+thioredoxin disulfide
Catalysed by RRM1 & RRM2 & RRM2B & TXN2 or TXN & RRM1 & RRM2 & RRM2B
Reaction pageLeft to rightBalancedEC 1.17.4.1cytosol
Human-GEM MAR04611CC BY 4.0Reference data
CHEBI:16174+dTDPCHEBI:16284+dTMP
Catalysed by DTYMK
Reaction pageReversibleBalancedEC 2.7.4.9mitochondrial matrix
Human-GEM MAR06612CC BY 4.0Reference data
CHEBI:16174+dTDPCHEBI:16284+dTMP
Catalysed by DTYMK
Reaction pageReversibleBalancedEC 2.7.4.9nucleus
Human-GEM MAR06613CC BY 4.0Reference data
CHEBI:16174+dTTPCHEBI:16284+dTDP
Catalysed by NME3 or NME4 or NME7 or NME6 or NME1 or NME2
Reaction pageReversibleBalancedEC 2.7.4.6cytosol
Human-GEM MAR06614CC BY 4.0Reference data
Other names
8 names
Resolves to: CHEBI:16284
- Also called
- 2'-dATP2'-deoxy-ATP2'-deoxyadenosine 5'-triphosphate2'-deoxyadenosine triphosphatedATPDeoxyadenosine 5'-triphosphateDeoxyadenosine triphosphate
- Systematic name
- 2'-deoxyadenosine 5'-(tetrahydrogen triphosphate)