CHEBI:16497

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

94 compounds within 3 steps: 4 in 1, 12 in 2, 78 in 3

One step

dUMPReach from here →
1. thymidine kinase (deoxyuridine)
No catalyst recordedcytosolOne of 2 routes
CHEBI:28862Reach from here →
1. ATP:dGDP phosphotransferase
Catalysed by NME4, NME6, NME1, NME2 and 2 morecytosolOne of 12 routes
dGMPReach from here →
1. 2-Deoxyguanosine 5-Triphosphate Pyrophosphohydrolase
Catalysed by ITPAextracellular space
dCDPReach from here →
1. UMP/CMP kinase (dCDP)
No catalyst recordedcytosolOne of 2 routes

Two steps

pyruvateReach from here →
1. ATP:dGDP phosphotransferase
2. dGTP:pyruvate 2-O-phosphotransferase
Catalysed by NME4, NME6, NME1, NME2 and 4 morecytosol
thioredoxin dithiolReach from here →
1. ATP:dGDP phosphotransferase
2. 2-Deoxyuridine 5-Diphosphate:Oxidized-Thioredoxin 2-Oxidoreductase
Catalysed by NME4, NME6, NME1, NME2 and 7 morecytosol, mitochondrial matrixOne of 2 routes

Three steps

2-hydroxybutyric acidReach from here →
Catalysed by NME4, NME6, NME1, NME2 and 10 morecytosol, extracellular spaceOne of 2 routes
acetoacetateReach from here →

CHEBI:16174Reach from here →

Catalysed by ITPAextracellular space, mitochondrial matrix

CHEBI:16284Reach from here →

Catalysed by NME4, NME6, NME1, NME2 and 2 morecytosol, mitochondrial matrixOne of 3 routes

2'-deoxyuridineReach from here →

Catalysed by NT5C, NT5McytosolOne of 3 routes

2'-deoxyguanosineReach from here →

Catalysed by ITPA, ACP3, NT5E, NT5C2 and 6 moreextracellular space, cytosolOne of 5 routes

7,8-dihydrofolateReach from here →

Catalysed by TYMScytosolOne of 2 routes

dCMPReach from here →

Catalysed by NME4, NME6, NME1, NME2 and 2 morecytosolOne of 18 routes

IMPReach from here →

Catalysed by ITPA, NT5C2extracellular space

dCTPReach from here →

Catalysed by NME4, NME6, NME1, NME2 and 2 morecytosolOne of 11 routes

dUTPReach from here →

Catalysed by DUTcytosol

dTMPReach from here →

Catalysed by TYMScytosolOne of 2 routes

Catalysed by NME4, NME6, NME1, NME2 and 4 more

cytosol, mitochondrial matrix

One of 4 routes

acetylpyruvateReach from here →

Catalysed by NME4, NME6, NME1, NME2 and 5 morecytosol

all-trans-retinoic acidReach from here →

Catalysed by NME4, NME6, NME1, NME2 and 10 morecytosol, extracellular spaceOne of 2 routes

(S)-malateReach from here →

Catalysed by NME4, NME6, NME1, NME2 and 5 morecytosolOne of 2 routes

L-leucineReach from here →

Catalysed by NME4, NME6, NME1, NME2 and 7 morecytosol, mitochondrial matrixOne of 2 routes

2'-deoxycytidineReach from here →

Catalysed by NME4, NME6, NME1, NME2 and 11 morecytosolOne of 8 routes

alpha-D-glucosamine 6-phosphateReach from here →

Catalysed by NME4, NME6, NME1, NME2 and 5 morecytosol, mitochondrial matrix

keto-D-fructose 6-phosphateReach from here →

Catalysed by NME4, NME6, NME1, NME2 and 6 morecytosol, mitochondrial matrix

CHEBI:15971Reach from here →

Catalysed by NME4, NME6, NME1, NME2 and 7 morecytosol, mitochondrial matrixOne of 2 routes

guanineReach from here →

Catalysed by ITPA, ACP3, NT5E, NT5C2 and 7 moreextracellular space, cytosolOne of 2 routes

2-methyl-3-oxopropanoic acidReach from here →

Catalysed by NME4, NME6, NME1, NME2 and 5 morecytosol, mitochondrial matrix

L-valineReach from here →

Catalysed by NME4, NME6, NME1, NME2 and 7 morecytosol, mitochondrial matrixOne of 2 routes

oxaloacetateReach from here →

Catalysed by NME4, NME6, NME1, NME2 and 5 morecytosol, mitochondrial matrixOne of 3 routes

L-arginineReach from here →

Catalysed by NME4, NME6, NME1, NME2 and 7 morecytosol, mitochondrial matrix

(S)-lactateReach from here →

Catalysed by NME4, NME6, NME1, NME2 and 9 morecytosol

2-oxobutanoateReach from here →

Catalysed by NME4, NME6, NME1, NME2 and 5 morecytosol

2-oxoglutaramateReach from here →

Catalysed by NME4, NME6, NME1, NME2 and 5 morecytosolOne of 2 routes

3-fumarylpyruvateReach from here →

Catalysed by NME4, NME6, NME1, NME2 and 5 morecytosol

CHEBI:16857Reach from here →

Catalysed by NME4, NME6, NME1, NME2 and 7 morecytosol, mitochondrial matrixOne of 2 routes

(R)-3-hydroxybutyric acidReach from here →

Catalysed by NME4, NME6, NME1, NME2 and 10 morecytosol, extracellular spaceOne of 2 routes

3-hydroxypyruvateReach from here →

Catalysed by NME4, NME6, NME1, NME2 and 5 morecytosol

L-isoleucineReach from here →

Catalysed by NME4, NME6, NME1, NME2 and 7 morecytosol, mitochondrial matrixOne of 2 routes

CHEBI:17203Reach from here →

Catalysed by NME4, NME6, NME1, NME2 and 7 morecytosol, mitochondrial matrixOne of 2 routes

aceneuramateReach from here →

Catalysed by NME4, NME6, NME1, NME2 and 5 morecytosol

5'-deoxyadenosineReach from here →

Catalysed by NME4, NME6, NME1, NME2 and 6 morecytosol

sulfiteReach from here →

Catalysed by NME4, NME6, NME1, NME2 and 8 morecytosol, mitochondrial matrix

L-cysteineReach from here →

Catalysed by NME4, NME6, NME1, NME2 and 7 morecytosol, mitochondrial matrixOne of 2 routes

uracilReach from here →

Catalysed by NT5C, NT5M, UPP2, UPP1cytosolOne of 2 routes

inosineReach from here →

Catalysed by ITPA, ACP3, NT5E, NT5C2 and 6 moreextracellular space, cytosolOne of 8 routes

thymidineReach from here →

Catalysed by TYMS, ACP3, NT5E, NT5C2 and 7 morecytosolOne of 4 routes

CHEBI:17895Reach from here →

Catalysed by NME4, NME6, NME1, NME2 and 7 morecytosol, mitochondrial matrixOne of 2 routes

CHEBI:18019Reach from here →

Catalysed by NME4, NME6, NME1, NME2 and 7 morecytosol, mitochondrial matrixOne of 2 routes

triphosphateReach from here →

Catalysed by NME4, NME6, NME1, NME2 and 3 morecytosol