2-oxobutanoate

Structure

Identity from ChEBI, geometry from PubChem. Not evidence.

What it touches on the way

What the reference databases state

• 2-oxobutanoate+proton+thiamine(1+) diphosphate→carbon dioxide+2-(alpha-Hydroxypropyl)thiamine diphosphate

  Catalysed by BCKDHA & BCKDHB

  Reaction pageLeft to rightBalance undeterminableEC 1.2.4.4mitochondrial matrix

  Human-GEM MAR03800CC BY 4.0Reference data

• water+L,L-cystathionine→2-oxobutanoate+L-cysteine+proton+ammonium

  Catalysed by CTH

  Reaction pageLeft to rightBalancedEC 4.4.1.1cytosol

  Human-GEM MAR03881CC BY 4.0Reference data

• CHEBI:16857→2-oxobutanoate+proton+ammonium

  Catalysed by SDS or SDSL

  Reaction pageLeft to rightBalancedEC 4.3.1.19cytosol

  Human-GEM MAR04348CC BY 4.0Reference data

• 2-oxobutanoate+proton→2-oxobutanoate+proton

  Transported by SLC16A8 or SLC16A6 or SLC16A7 or SLC16A3 or SLC16A1 or SLC16A4 or SLC16A5

  Reaction pageLeft to rightBalancedcytosol, mitochondrial matrix

  Human-GEM MAR05348CC BY 4.0Reference data

• 2-oxobutanoate+proton→2-oxobutanoate+proton

  Transported by SLC16A8 or SLC16A6 or SLC16A7 or SLC16A3 or SLC16A1 or SLC16A4 or SLC16A5

  Reaction pageLeft to rightBalancedmitochondrial matrix, mitochondrial intermembrane space, cytosol

  Human-GEM MAR05349CC BY 4.0Reference data

• 2-hydroxybutyric acid+NAD(+)⇌2-oxobutanoate+proton+NADH(2-)

  Catalysed by LDHB or LDHC or LDHAL6A or LDHAL6B

  Reaction pageReversibleBalancedEC 1.1.1.27cytosol

  Human-GEM MAR05351CC BY 4.0Reference data

• L-alpha-aminobutyric acid+2-oxoglutarate(2-)⇌2-oxobutanoate+L-glutamate(1-)

  Catalysed by GPT

  Reaction pageReversibleBalancedEC 2.6.1.2cytosol

  Human-GEM MAR06970CC BY 4.0Reference data

• water+CHEBI:27760⇌2-oxobutanoate+proton+ammonium+CHEBI:16633

  Catalysed by CTH

  Reaction pageReversibleBalancedEC 4.4.1.1cytosol

  Human-GEM MAR07134CC BY 4.0Reference data

• water+selenomethionine⇌2-oxobutanoate+proton+MAM02469c+ammonium

  Catalysed by CTH

  Reaction pageReversibleBalancedEC 4.4.1.1cytosol

  Human-GEM MAR07137CC BY 4.0Reference data

• 2-oxobutanoate+CHEBI:1146900+NAD(+)→carbon dioxide+NADH(2-)+propionyl-CoA

  Reaction pageLeft to rightBalancedcytosol

  Human-GEM MAR08442CC BY 4.0Reference data

• 2-oxobutanoate⇌

  Reaction pageReversibleBalance undeterminableextracellular space

  Human-GEM MAR11391CC BY 4.0Reference data

• 2-oxobutanoate+proton⇌2-oxobutanoate+proton

  Transported by SLC16A7

  Reaction pageReversibleBalancedextracellular space, cytosol

  Human-GEM MAR11785CC BY 4.0Reference data

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Where it reaches

9 systems, 17 regions, 34 tissues, 34 transporter routes — routes, not measurements: transporters known to carry 2-oxobutanoate are expressed there, and no source reports it arriving.

Resolves to: 2-oxobutanoate

Also called

2-Ketobutanoate2-ketobutyrate2-Oxobutyratealpha-ketobutyratealpha-oxobutyrateα-ketobutyrateα-oxobutyrate