Compound
pregnenolone
No description recorded for this entry yet. Everything this graph holds about pregnenolone is below.
Structure
- Class
- Organic compound
- Formula
- C21H32O2
- Mass
- 316.485 g/mol
- Charge
- 0
- InChIKey
- ORNBQBCIOKFOEO-QGVNFLHTSA-N
- SMILES
- [H][C@@]12CC=C3C[C@@H](O)CC[C@]3(C)[C@@]1([H])CC[C@]1(C)[C@@H](C(C)=O)CC[C@@]21[H]
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence — none of it carries a grade.
What it touches on the way
A finding says pregnenolone moved an endpoint. This is the biology in between: the proteins and reactions it runs through to get there. It is where to look for the two things a list of findings cannot answer — why a result might happen, and what else acts on the same machinery.
7 of these are proteins with a page of their own, and that is the door: a protein page says what else it carries, which is how one compound leads to the next.
Mechanistic reach
7 entities
7 entities reached, most connected first. Hub metabolites are excluded, so this is not a claim that the compound touches everything.
0 reported hops7 assembled from the scaffold
- CYP17A1ProteinUNIPROT:P05093metabolized byInferred only66 paths22 endpoints
- CYP11A1ProteinUNIPROT:P05108metabolized byInferred only50 paths25 endpoints
- SULT2A1ProteinUNIPROT:Q06520metabolized byInferred only21 paths21 endpoints
- CYP7B1ProteinUNIPROT:O75881metabolized byInferred only19 paths19 endpoints
- HSD3B1ProteinUNIPROT:P14060substrate ofInferred only18 paths18 endpoints
- HSD3B2ProteinUNIPROT:P26439substrate ofInferred only18 paths18 endpoints
- SULT2B1ProteinUNIPROT:O00204metabolized byInferred only4 paths4 endpoints
What the reference databases state
The section above shows paths a projection assembled. This is the reference layer itself, one step from pregnenolone: what the cleared databases state it reacts with, is carried by, is converted to and takes part in, whether or not a projection has walked it yet.
Statements
12 statements
12 statements in 2 reference databases name pregnenolone — Human-GEM, Rhea. Press a relation to see only its rows; every count is the rows behind it.
- pregnenolone is converted to pregn-5-ene-3,20-dioneCompoundRhea RHEA:43924Inferred only
- pregn-5-ene-3,20-dione is converted to pregnenoloneCompoundRhea RHEA:43924Inferred only
- pregnenolone is metabolised by CYP11A1ProteinRhea RHEA:34343Inferred only
- pregnenolone is metabolised by CYP11A1ProteinRhea RHEA:35739Inferred only
- pregnenolone is metabolised by CYP17A1ProteinHuman-GEM MAR01944Inferred only
- pregnenolone is metabolised by CYP17A1ProteinHuman-GEM MAR01945Inferred only
- pregnenolone is metabolised by CYP17A1ProteinRhea RHEA:50236Inferred only
- pregnenolone is metabolised by CYP7B1ProteinRhea RHEA:46196Inferred only
- pregnenolone is metabolised by SULT2A1ProteinRhea RHEA:52356Inferred only
- pregnenolone is metabolised by SULT2B1ProteinRhea RHEA:52356Inferred only
- pregnenolone is a substrate of HSD3B1ProteinRhea RHEA:43924Inferred only
- pregnenolone is a substrate of HSD3B2ProteinRhea RHEA:43924Inferred only
On the label
The findings above state the dose each study gave. This is the dose a label declares, which is the one a person actually meets. A label is a manufacturer’s statement about a package; nothing here says what the product does.
Labelled products
86 products
86 products in the NIH Dietary Supplement Label Database list pregnenolone as an active ingredient. 86 of them state an amount per serving in mg, from 1.25 to 150 mg.
86 labels state an amount0 do not
- AbsonutrixPregnenolone Complex100 mgper 0.59 mLDSLD:322368
- Adaptogen ResearchPregnenolone 25 mgWild Yam · Pregnenolone (Form: derived from Wild Yam) Note: micronized25 mgper 1 Capsule(s)DSLD:247242
- Allergy Research GroupPregnenolone 150150 mgper 1 Tablet(s)DSLD:20359
- Allergy Research GroupPregnenolone 5050 mgper 1 Tablet(s)DSLD:183651
- BioGenesis NutraceuticalsAdrenal Support Plus7 mgper 2 Capsule(s)DSLD:20760
- BulkSupplements.comPregnenolone20 mgper 20 mgDSLD:254351
- BulkSupplements.comPregnenolone20 mgper 20 mgDSLD:254354
- BulkSupplements.comPregnenoloneWild Yam20 mgper 20 mgDSLD:254357
- BulkSupplements.comPregnenolone20 mgper 20 mgDSLD:311630
- BulkSupplements.comPregnenolone20 mgper 20 mgDSLD:311633
- BulkSupplements.comPregnenolone Powder 20 mg20 mgper 20 mgDSLD:330357
- CHK NutritionPregnenolone100 mgper 1 Capsule(s)DSLD:12005
Show the remaining 74
- Confidence USAFe-Mon-970 mgper 2 Capsule(s)DSLD:246710
- Core NutritionalsFURY Cherry Burst10 mgper 12.4 Gram(s)DSLD:269757
- Core NutritionalsFURY Sangria10 mgper 11.8 Gram(s)DSLD:297984
- Core NutritionalsFURY Tropic Thunder10 mgper 12.4 Gram(s)DSLD:269760
- Core NutritionalsPregnenolone25 mgper 1 Capsule(s)DSLD:269442
- Core NutritionalsPregnenolone25 mgper 1 Capsule(s)DSLD:298259
- Core NutritionalsZONE Arnold Palmer10 mgper 8 Gram(s)DSLD:270175
- Core NutritionalsZONE Berrylicious10 mgper 7.9 Gram(s)DSLD:298368
- Core NutritionalsZONE Sour Candy10 mgper 8 Gram(s)DSLD:298369
- Country LifePregnenolone 30 mg30 mgper 1 Capsule(s)DSLD:14107
- DCDHEA Plus25 mgper 1 Capsule(s)DSLD:267162
- DCFormula 9010 mgper 1 Capsule(s)DSLD:266291
- Designs for HealthPregnenolone CRT30 mgper 1 Tablet(s)DSLD:22794
- Douglas LaboratoriesPregnenolone 25 mg25 mgper 0.5 Tablet(s)DSLD:10163
- Douglas LaboratoriesPregnenolone 25 mg25 mgper 1 Tablet(s)DSLD:232050
- Douglas LaboratoriesPregnenolone 5 mg5 mgper 0.5 Bisected Tablet(s)DSLD:30809
- Eurovital NutraceuticalsPregnenolone 50 mg50 mgper 1 Vegetarian Capsule(s)DSLD:66091
- Foster RegalDHEA Plus25 mgper 1 Capsule(s)DSLD:296993
- Greens First FemalePregnenolone 50 mg50 mgper 1 Capsule(s)DSLD:181048
- Healthy Choice NaturalsTriple Hormone25 mgper 1 Capsule(s)DSLD:11318
- HoltraCeuticalsAdrenal Boost25 mgper 3 Capsule(s)DSLD:19219
- HoltraCeuticalsDHEA/Pregnenolone 25 mg/100 mg100 mgper 1 Capsule(s)DSLD:19399
- HoltraCeuticalsPregnenolone100 mgper 1 Capsule(s)DSLD:19837
- InfoWars LifeThe Real Red Pill Plus50 mgper 2 Capsule(s)DSLD:218867
- KarunaPregnenolone50 mgper 1 Capsule(s)DSLD:25236
- Life ExtensionPregnenolone 100 mg100 mgper 1 Capsule(s)DSLD:231683
- Life ExtensionPregnenolone 100 mg100 mgper 1 Capsule(s)DSLD:58756
- Life ExtensionPregnenolone 100 mg100 mgper 1 Capsule(s)DSLD:58758
- Life ExtensionPregnenolone 50 mg50 mgper 1 Capsule(s)DSLD:231650
- Life ExtensionPregnenolone 50 mg50 mgper 1 Capsule(s)DSLD:58616
- LifeLinkPregnenolone 10 mg10 mgper 1 Capsule(s)DSLD:11745
- LifeLinkPregnenolone 30 mg30 mgper 1 Capsule(s)DSLD:11746
- LifeLinkPregnenolone 30 mg30 mgper 1 Capsule(s)DSLD:11748
- LifeLinkPregnenolone 50 mg50 mgper 1 Capsule(s)DSLD:11750
- LifeLinkPregnenolone 50 mg50 mgper 1 Capsule(s)DSLD:11751
- Nature's PlusUltra PregnenolonePregnenolone Note: pharmaceutical grade50 mgper 1 Capsule(s)DSLD:15368
- Nature's SunshinePregnenolone20 mgper 1 Capsule(s)DSLD:4595
- Natures PlusUltra PregnenolonePregnenolone Note: pharmaceutical grade50 mgper 1 Capsule(s)DSLD:223061
- NHC Natural Healthy ConceptsPregnenolone Micronized10 mgper 1 Tablet(s)DSLD:256205
- Nova NutritionsPregnenolone 30 mg30 mgper 1 Tablet(s)DSLD:229272
- NutriCologyPregnenolone 100100 mgper 1 Tablet(s)DSLD:198373
- NutriCologyPregnenolone 150150 mgper 1 Tablet(s)DSLD:191139
- NutriCologyPregnenolone 5050 mgper 1 Tablet(s)DSLD:235415
- Oceanus NaturalsPerformance Tablet5 mgper 1 Tablet(s)DSLD:5891
- Patient One 1 MediNutritionalsAdrenal D-Stress10 mgper 3 Capsule(s)DSLD:249140
- Premier Research LabsPremier Pregnenolone100 mgper 1 Capsule(s)DSLD:297564
- Pure EncapsulationsPregnenolone 10 mg10 mgper 1 Capsule(s)DSLD:184836
- Pure EncapsulationsPregnenolone 10 mg10 mgper 1 Capsule(s)DSLD:218864
- Pure EncapsulationsPregnenolone 30 mg30 mgper 1 Capsule(s)DSLD:204895
- Pure EncapsulationsPregnenolone 30 mg30 mgper 1 Capsule(s)DSLD:218869
- Pure EncapsulationsPregnenolone 30 mg30 mgper 1 Capsule(s)DSLD:218889
- Pure EncapsulationsPregnenolone 30 mg30 mgper 1 Capsule(s)DSLD:278249
- Puritan's PridePregnenolone 50 mg50 mgper 1 Capsule(s)DSLD:286031
- Return HealthyPregnenolone CR30 mgper 1 Tablet(s)DSLD:313319
- Source NaturalsIntimate Response1.25 mgper 1 Tablet(s)DSLD:213861
- Source NaturalsPregnenolone 25 mg25 mgper 1 Tablet(s)DSLD:275398
- Source NaturalsPregnenolone 25 mg25 mgper 1 Tablet(s)DSLD:296155
- Source NaturalsPregnenolone 50 mg50 mgper 1 Tablet(s)DSLD:296156
- Source NaturalsPregnenolone Cherry Flavored 25 mg25 mgper 1 Tablet(s)DSLD:296153
- Source NaturalsWellness D-mmunity 125 MCG10 mgper 2 Capsule(s)DSLD:296375
- Source NaturalsWellness D-mmunity 125 MCG10 mgper 2 Capsule(s)DSLD:296376
- Supplement SpotPregnenolone 100 mg100 mgper 1 Capsule(s)DSLD:265192
- Supplement SpotPregnenolone 150 mg150 mgper 1 Capsule(s)DSLD:265193
- SwansonPregnenolone 50 mg Super Strength50 mgper 1 Capsule(s)DSLD:188898
- Swanson Premium BrandPregnenolone 10 mg10 mgper 1 Capsule(s)DSLD:175359
- Swanson UltraDHEA and Pregnenolone Complex100 mgper 1 Veggie Capsule(s)DSLD:240042
- Swanson UltraHigh Potency Pregnenolone 25 mg25 mgper 1 Capsule(s)DSLD:203724
- Terry NaturallyAdrenaplex15 mgper 1 Capsule(s)DSLD:202329
- Terry NaturallyAdrenaplex15 mgper 1 Capsule(s)DSLD:304487
- Terry NaturallyAdrenaplex15 mgper 1 Capsule(s)DSLD:39340
- Terry NaturallyAdrenaplex15 mgper 1 Capsule(s)DSLD:54565
- Vitamin WorldYouth Guard Pregnenolone 50 mg50 mgper 1 Capsule(s)DSLD:1324
- Wonder LaboratoriesDHEA Plus25 mgper 1 Capsule(s)DSLD:315172
- XYMOGENMax Brain5 mgper 1 Capsule(s)DSLD:50373
Each row links to its label record at the NIH Office of Dietary Supplements, which is where the declaration lives. CC0.
Other names
5 names
Every name this graph resolves to pregnenolone. Searching any of them lands here.
- Also called
- (3BETA)-3-HYDROXYPREGN-5-EN-20-ONE5-Pregnen-3beta-ol-20-oneST 21:2;O2
- Systematic name
- 3beta-hydroxypregn-5-en-20-one3β-hydroxypregn-5-en-20-one