Loading the page.
Proteins/UNIPROT:P20711
Catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine and L-5-hydroxytryptophan to serotonin..
Function from UniProtKB (P20711), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 1 · substrate of
1 compound
1 compound.
0 reported routes1 assembled route
1 row
82 statements
82 statements · 8 reference databases · Subject: DDC · Sources: Bgee, Hetionet, Human Protein Atlas, Human-GEM, Reactome, Rhea, UniProt, WikiPathways
10 reactions
5-hydroxytryptophan+protoncarbon dioxide+serotonin
Catalysed by DDC
Reaction pageLeft to rightBalancedEC 4.1.1.28cytosol
Human-GEM MAR04545CC BY 4.0Reference data
proton+L-phenylalaninecarbon dioxide+2-phenylethylamine
Catalysed by DDC
Reaction pageLeft to rightBalancedEC 4.1.1.28cytosol
2 names
Resolves to: DDC
proton+L-tryptophancarbon dioxide+tryptamine
Catalysed by DDC
Reaction pageLeft to rightBalancedEC 4.1.1.28cytosol
Human-GEM MAR06707CC BY 4.0Reference data
MAM01106c+protonMAM01105c+carbon dioxide
Catalysed by DDC
Reaction pageLeft to rightBalancedEC 4.1.1.28cytosol
Human-GEM MAR06718CC BY 4.0Reference data
proton+CHEBI:15765carbon dioxide+dopamine
Catalysed by DDC
Reaction pageLeft to rightBalancedEC 4.1.1.28cytosol
Human-GEM MAR06731CC BY 4.0Reference data
MAM02876cMAM00231c+carbon dioxide+2proton
Catalysed by DDC
Reaction pageLeft to rightUnbalancedEC 4.1.1.28cytosol
Human-GEM MAR06740CC BY 4.0Reference data
proton+CHEBI:17895carbon dioxide+MAM03099c
Catalysed by DDC
Reaction pageLeft to rightBalancedEC 4.1.1.28cytosol
Human-GEM MAR06787CC BY 4.0Reference data
CHEBI:17380+protonMAM00786c+carbon dioxide
Catalysed by DDC
Reaction pageLeft to rightBalancedEC 4.1.1.28cytosol
Human-GEM MAR08091CC BY 4.0Reference data
L-dopa+hydrondopamine+carbon dioxide
Catalysed by DDC
Reaction pageDirection not assertedBalanced
Rhea RHEA:12272CC BY 4.0Reference data
5-hydroxy-L-tryptophan+hydronserotonin+carbon dioxide
Catalysed by DDC
Reaction pageDirection not assertedBalanced
Rhea RHEA:18533CC BY 4.0Reference data