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Proteins/UNIPROT:O14521
Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). SDH also oxidizes malate to the non-canonical enol form of oxaloacetate, enol-oxaloacetate (By similarity). Enol-oxaloacetate, which is a potent inhibitor of the succinate dehydrogenase activity, is further isomerized into keto-oxaloacetate (By similarity)..
Function from UniProtKB (O14521), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
7 rows
80 statements
80 statements · 4 reference databases · Subject: SDHD · Sources: Hetionet, Human-GEM, Reactome, WikiPathways
1 reaction
fumaric acid+ubiquinolsuccinate(2-)+ubiquinones
Catalysed by SDHD & SDHB & SDHA & SDHC
Reaction pageReversibleBalancedEC 1.3.5.1mitochondrial matrix
Human-GEM MAR04652CC BY 4.0Reference data
8 names
Resolves to: SDHD