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Proteins/UNIPROT:Q5SVS4
Antiporter that transports inorganic anions (sulfate, sulfite, thiosulfate and phosphate) and, to a lesser extent, a variety of dicarboxylates (e.g. malonate, malate and citramalate) and, even more so, aspartate. The sulfate/sulfate exchange is much higher than the phosphate/phosphate and malate/malate exchanges. The transport affinities is higher for sulfate and thiosulfate than for any other substrate. May catalyze the export of sulfite and thiosulfate (the hydrogen sulfide degradation products) from the mitochondria, thereby modulating the level of the hydrogen sulfide (Probable). Also may mediate a very low unidirectional transport of sulfate, phosphate and (S)-malate..
Function from UniProtKB (Q5SVS4), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
39 statements
39 statements · 3 reference databases · Subject: SLC25A30 · Sources: Bgee, Hetionet, Rhea
17 reactions
hydrogenphosphatehydrogenphosphate
Transported by SLC25A14 or UCP2 or SLC25A30 or SLC17A7 or SLC17A6 or XPR1
Reaction pageLeft to rightBalanced
Rhea RHEA:32823CC BY 4.0Reference data
Transported by SLC25A14 or SLC25A30 or SLC26A7
Reaction pageDirection not asserted
4 names
Resolves to: SLC25A30
Rhea RHEA:34983CC BY 4.0Reference data
(S)-malate+sulfate(S)-malate+sulfate
Transported by SLC25A14 or SLC25A30 or SLC25A10
Reaction pageDirection not assertedBalanced
Rhea RHEA:71615CC BY 4.0Reference data
sulfate+hydrogenphosphatesulfate+hydrogenphosphate
Transported by SLC25A14 or SLC25A30 or SLC25A10
Reaction pageDirection not assertedBalanced
Rhea RHEA:71631CC BY 4.0Reference data
oxalate+sulfateoxalate+sulfate
Transported by SLC25A14 or SLC26A2 or SLC25A30 or SLC26A6 or SLC26A1
Reaction pageDirection not assertedBalanced
Rhea RHEA:72275CC BY 4.0Reference data
malonate+sulfatemalonate+sulfate
Transported by SLC25A14 or SLC25A30 or SLC25A10
Reaction pageDirection not assertedBalanced
Rhea RHEA:73195CC BY 4.0Reference data
maleate+sulfatemaleate+sulfate
Transported by SLC25A14 or SLC25A30
Reaction pageDirection not assertedBalanced
Rhea RHEA:73199CC BY 4.0Reference data
sulfite+sulfatesulfite+sulfate
Transported by SLC25A14 or SLC25A30
Reaction pageDirection not assertedBalanced
Rhea RHEA:73207CC BY 4.0Reference data
thiosulfate+sulfatethiosulfate+sulfate
Transported by SLC25A14 or SLC25A30 or SLC26A1 or SLC25A10
Reaction pageDirection not assertedBalanced
Rhea RHEA:73215CC BY 4.0Reference data
(3S)-citramalate+sulfate(3S)-citramalate+sulfate
Transported by SLC25A14 or SLC25A30
Reaction pageDirection not assertedBalanced
Rhea RHEA:73223CC BY 4.0Reference data
(3R)-citramalate+sulfate(3R)-citramalate+sulfate
Transported by SLC25A14 or SLC25A30
Reaction pageDirection not assertedBalanced
Rhea RHEA:73227CC BY 4.0Reference data
L-aspartate+sulfateL-aspartate+sulfate
Transported by SLC25A14 or SLC25A30
Reaction pageDirection not assertedBalanced
Rhea RHEA:73395CC BY 4.0Reference data