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Proteins/UNIPROT:Q9Y345
Sodium- and chloride-dependent glycine transporter. Terminates the action of glycine by its high affinity sodium-dependent reuptake into presynaptic terminals. May be responsible for the termination of neurotransmission at strychnine-sensitive glycinergic synapses..
[Isoform 2]: Lacks sodium- and chloride-dependent glycine transporter activity..
[Isoform 3]: Lacks sodium- and chloride-dependent glycine transporter activity..
Function from UniProtKB (Q9Y345), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 1 · transported by
1 compound
1 compound.
0 reported routes1 assembled route
2 rows
28 statements
28 statements · 5 reference databases · Subject: SLC6A5 · Sources: Hetionet, Human-GEM, Reactome, Rhea, WikiPathways
5 reactions
chlorine(.)+glycine+3sodium(1+)chlorine(.)+glycine+3sodium(1+)
Transported by SLC6A5
Reaction pageLeft to rightBalancedextracellular space, cytosol
Human-GEM MAR05457CC BY 4.0Reference data
4 names
Resolves to: SLC6A5
Reaction pageLeft to rightBalancedextracellular space, cytosol
Human-GEM MAR09616CC BY 4.0Reference data
CHEBI:240943+chlorine(.)+3sodium(1+)CHEBI:240943+chlorine(.)+3sodium(1+)
Transported by SLC6A5
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR11450CC BY 4.0Reference data
MAM00825c+chlorine(.)+3sodium(1+)MAM00825e+chlorine(.)+3sodium(1+)
Transported by SLC6A5
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR11453CC BY 4.0Reference data
glycine+chloride+3sodium(1+)glycine+chloride+3sodium(1+)
Transported by SLC6A5
Reaction pageDirection not assertedBalanced
Rhea RHEA:70695CC BY 4.0Reference data