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Reference

Evidence

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Outcomes
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Reach

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Materials
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Diseases

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tryptamine

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

Inferred

Every route here is a hypothesis drawn from reference reactions (Rhea and Human-GEM), not a finding. Currency species such as water, ATP and NAD(H) never form a step. Evidence key

5 compounds within 3 steps: 2 in 1, 1 in 2, 2 in 3

Does it reach a compound?

One step

indole-3-acetaldehydeReach from here →
1. Tryptamine:oxygen oxidoreductase(deaminating)
Catalysed by AOC1, MAOA, MAOBcytosolOne of 2 routes
N-methyltryptamineReach from here →
1. S-Adenosyl-L-methionine:amine N-methyltransferase
Catalysed by INMTcytosol

Two steps

(indol-3-yl)acetateReach from here →
1. Tryptamine:oxygen oxidoreductase(deaminating)
2. Indole-3-acetaldehyde:NAD+ oxidoreductase
Catalysed by AOC1, MAOA, MAOB, ALDH2 and 4 morecytosolOne of 2 routes

Three steps

a dicarboxylateReach from here →
Catalysed by AOC1, MAOA, MAOB, ALDH2 and 6 morecytosol, inner side of the membrane, outer side of the membraneOne of 2 routes
methyl (indol-3-yl)acetateReach from here →

Catalysed by AOC1, MAOA, MAOB, ALDH2 and 6 morecytosol