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A reference for what the literature reports. Not medical advice.

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Compound

succinic semialdehyde

CHEBI:16265ChEBI

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What it touches on the way

Inferred

Not reported; assembled from reference reactions.

Mechanistic reach

2 entities

2 entities reached.

0 reported hops2 assembled from the scaffold

ABATProteinUNIPROT:P80404substrate ofInferred only15 paths15 endpoints
ALDH5A1ProteinUNIPROT:P51649metabolized byInferred only7 paths7 endpoints

What the reference databases state

Statements

5 statements

5 statements · 1 reference database · Subject: succinic semialdehyde · Sources: Human-GEM

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succinic semialdehyde is converted to 4-aminobutanoateCompoundHuman-GEM MAR04693Inferred only
4-aminobutanoate is converted to succinic semialdehydeCompoundHuman-GEM MAR04693Inferred only
succinic semialdehyde is converted to 4-hydroxybutanoateCompoundHuman-GEM MAR11565Inferred only
succinic semialdehyde is metabolised by ALDH5A1ProteinHuman-GEM MAR04285Inferred only
succinic semialdehyde is a substrate of ABATProteinHuman-GEM MAR04693Inferred only

Reactions

7 reactions

water+NAD(+)+succinic semialdehyde2proton+NADH(2-)+succinate(2-)
Catalysed by ALDH5A1
Reaction pageLeft to rightBalancedEC 1.2.1.24, 1.2.1.16GO:0005759
Human-GEM MAR04285CC BY 4.0Reference data
water+NADP(3-)+succinic semialdehyde2proton+NADPH(4-)+succinate(2-)
Reaction pageLeft to rightBalancedEC 1.2.1.16GO:0005759
Human-GEM MAR04287CC BY 4.0Reference data
4-aminobutanoate+2-oxoglutarate(2-)L-glutamate(1-)+succinic semialdehyde
Catalysed by ABAT
Reaction pageReversibleBalancedEC 2.6.1.19GO:0005759
Human-GEM MAR04693CC BY 4.0Reference data
proton+NADH(2-)+succinic semialdehydeNAD(+)+4-hydroxybutanoate
Reaction pageLeft to rightBalancedEC 2.3.1.9GO:0005759
Human-GEM MAR11565CC BY 4.0Reference data
succinic semialdehydesuccinic semialdehyde
Reaction pageReversibleBalancedGO:0005759, GO:0005829
Human-GEM MAR11825CC BY 4.0Reference data
succinic semialdehydesuccinic semialdehyde
Reaction pageReversibleBalancedEC 3.1.2.2GO:0005829, GO:0005615
Human-GEM MAR11826CC BY 4.0Reference data
succinic semialdehyde
Reaction pageReversibleBalance undeterminableGO:0005615
Human-GEM MAR11827CC BY 4.0Reference data

Other names

9 names

Resolves to: succinic semialdehyde

Also called: 3-formylpropanoic acid3-formylpropionic acid4-Oxobutanoatebeta-formylpropionic acidsuccinaldehydic acidSuccinate semialdehydesuccinic acid semialdehydeβ-formylpropionic acid
Systematic name: 4-oxobutanoic acid