Compound

2-oxoglutaramate

CHEBI:16769ChEBI

Structure

2D depiction · 3D model shown

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A generated conformer of 2-oxoglutaramate — one low-energy arrangement PubChem computed, not a measured structure. Hydrogens are not drawn; the formula counts them.

Class: Organic compound, anion
Formula: C5H6NO4
Mass: 144.106 g/mol
Charge: -1
InChIKey: COJBGNAUUSNXHX-UHFFFAOYSA-M
SMILES: NC(=O)CCC(=O)C(=O)[O-]
Look it up: ChEBI PubChem By InChIKey

Identity from ChEBI, geometry from PubChem. Not evidence.

What it touches on the way

Mechanistic reach

3 entities

3 entities reached.

0 reported hops3 assembled from the scaffold

L-glutamineCompoundCHEBI:18050converted toInferred only47 paths26 endpoints
KYAT1ProteinUNIPROT:Q16773substrate ofInferred only9 paths9 endpoints
NIT2ProteinUNIPROT:Q9NQR4substrate ofInferred only9 paths3 endpoints

What the reference databases state

Statements

6 statements

6 statements · 2 reference databases · Subject: 2-oxoglutaramate · Sources: Human-GEM, Rhea

Order

2-oxoglutaramate is converted to L-glutamineCompoundRhea RHEA:61260Inferred only
L-glutamine is converted to 2-oxoglutaramateCompoundRhea RHEA:61260Inferred only
2-oxoglutaramate is a substrate of KYAT1ProteinRhea RHEA:17593Inferred only
2-oxoglutaramate is a substrate of NIT2ProteinHuman-GEM MAR04114Inferred only
2-oxoglutaramate is a substrate of NIT2ProteinHuman-GEM MAR04115Inferred only
2-oxoglutaramate is a substrate of NIT2ProteinRhea RHEA:32963Inferred only

Reactions

17 reactions

2-oxoglutaramate+water2-oxoglutarate(2-)+proton+ammonium
Catalysed by NIT2
Reaction pageLeft to rightBalancedEC 3.5.1.3cytosol
Human-GEM MAR04114CC BY 4.0Reference data
2-oxoglutaramate+water2-oxoglutarate(2-)+proton+ammonium
Catalysed by NIT2
Reaction pageLeft to rightBalancedEC 3.5.1.3mitochondrial matrix
Human-GEM MAR04115CC BY 4.0Reference data
L-glutamine+pyruvate2-oxoglutaramate+L-alanine
Catalysed by KYAT1
Reaction pageLeft to rightBalancedEC 2.6.1.15, 2.6.1.63cytosol
Human-GEM MAR04196CC BY 4.0Reference data
L-glutamine+pyruvate2-oxoglutaramate+L-alanine
Catalysed by AADAT or KYAT3
Reaction pageLeft to rightBalancedEC 2.6.1.15, 2.6.1.63mitochondrial matrix
Human-GEM MAR04197CC BY 4.0Reference data
L-glutamine+pyruvate2-oxoglutaramate+L-alanine
Reaction pageDirection not assertedBalanced
Rhea RHEA:10400CC BY 4.0Reference data
3-phenylpyruvate+L-glutamine2-oxoglutaramate+L-phenylalanine
Catalysed by KYAT1
Reaction pageDirection not assertedBalanced
Rhea RHEA:17593CC BY 4.0Reference data
CHEBI:17811+L-glutamineCHEBI:57671+2-oxoglutaramate
Reaction pageDirection not assertedBalanced
Rhea RHEA:22920CC BY 4.0Reference data
4-methylsulfanyl-2-oxobutanoate+L-glutamine2-oxoglutaramate+L-methionine
Reaction pageDirection not assertedBalanced
Rhea RHEA:30391CC BY 4.0Reference data
2-oxoglutaramate+water2-oxoglutarate(2-)+ammonium
Catalysed by NIT2
Reaction pageLeft to rightBalanced
Rhea RHEA:32963CC BY 4.0Reference data
CHEBI:64796+L-glutamineCHEBI:65003+2-oxoglutaramate
Reaction pageDirection not assertedBalanced
Rhea RHEA:34147CC BY 4.0Reference data
CHEBI:65002+L-glutamineCHEBI:65069+2-oxoglutaramate
Reaction pageDirection not assertedBalanced
Rhea RHEA:34151CC BY 4.0Reference data
CHEBI:71965+L-glutamineCHEBI:71964+2-oxoglutaramate
Reaction pageDirection not assertedBalanced
Rhea RHEA:35775CC BY 4.0Reference data

Show the remaining 5

Other names

3 names

Resolves to: 2-oxoglutaramate

Also called: alpha-ketoglutaramateα-ketoglutaramate
Systematic name: 5-amino-2,5-dioxopentanoate