L-citrulline

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

616 compounds within 3 steps: 22 in 1, 174 in 2, 420 in 3

One step

L-leucineReach from here →
1. transport of citrulline and leucine (cytosol to extracellular)
No catalyst recordedextracellular space, cytosolOne of 2 routes
CHEBI:15699Reach from here →
1. transport of citrulline and homoserine (cytosol to extracellular)
Catalysed by SLC7A9, SLC3A1, SLC7A6extracellular space, cytosol
CHEBI:15971Reach from here →
1. transport of citrulline and histidine (cytosol to extracellular)
Catalysed by SLC7A5, SLC7A6extracellular space, cytosolOne of 4 routes
L-valineReach from here →
1. transport of citrulline and valine (cytosol to extracellular)
Catalysed by SLC7A9, SLC3A1, SLC7A6extracellular space, cytosol
L-arginineReach from here →
1. transport of arginine and citrulline (cytosol to extracellular)
Catalysed by SLC7A5, SLC7A6extracellular space, cytosolOne of 4 routes
CHEBI:16857Reach from here →
1. transport of citrulline and threonine (cytosol to extracellular)
Catalysed by SLC7A6extracellular space, cytosolOne of 2 routes
L-isoleucineReach from here →
1. transport of citrulline and isoleucine (cytosol to extracellular)
Catalysed by SLC7A6extracellular space, cytosolOne of 2 routes
CHEBI:17203Reach from here →
1. transport of citrulline and proline (cytosol to extracellular)
Catalysed by SLC7A6extracellular space, cytosolOne of 2 routes
L-cysteineReach from here →
1. transport of citrulline and cysteine (cytosol to extracellular)
Catalysed by SLC7A6extracellular space, cytosolOne of 2 routes
CHEBI:17895Reach from here →
1. transport of citrulline and tyrosine (cytosol to extracellular)
Catalysed by SLC7A6extracellular space, cytosolOne of 2 routes
CHEBI:18019Reach from here →
1. transport of citrulline and lysine (cytosol to extracellular)
Catalysed by SLC7A5, SLC7A6extracellular space, cytosolOne of 4 routes
L-glutamineReach from here →
1. transport of citrulline and glutamine (cytosol to extracellular)
Catalysed by SLC7A6extracellular space, cytosolOne of 2 routes
isocyanateReach from here →
1. L-citrulline + H(+) = isocyanate + L-ornithine
Catalysed by LACC1
L-ornithineReach from here →
1. Amino Acid-Polyamine-Organocation (Apc) Tcdb:2.A.3.8.15
Catalysed by SLC7A9extracellular space, cytosolOne of 11 routes
glycineReach from here →
1. transport of citrulline and glycine (cytosol to extracellular)
Catalysed by SLC7A9, SLC3A1, SLC7A6extracellular space, cytosol
2-(N(omega)-L-arginino)succinateReach from here →
1. L-Citrulline:L-aspartate ligase (AMP-forming)
Catalysed by ASS1cytosolOne of 2 routes
L-methionineReach from here →
1. transport of citrulline and methionine (cytosol to extracellular)
Catalysed by SLC7A6extracellular space, cytosolOne of 2 routes
L-tryptophanReach from here →
1. transport of citrulline and tryptophan (cytosol to extracellular)
Catalysed by SLC7A9, SLC3A1, SLC7A6extracellular space, cytosol
L-alanineReach from here →
1. transport of alanine and citrulline (cytosol to extracellular)
Catalysed by SLC7A6extracellular space, cytosolOne of 2 routes
L-asparagineReach from here →
1. transport of asparagine and citrulline (cytosol to extracellular)
Catalysed by SLC7A9, SLC3A1, SLC7A6extracellular space, cytosol
L-phenylalanineReach from here →
1. transport of citrulline and phenylalanine (cytosol to extracellular)
Catalysed by SLC7A6extracellular space, cytosolOne of 2 routes
carbamoyl phosphateReach from here →
1. Carbamoyl-phosphate:L-ornithine carbamoyltransferase
Catalysed by OTCmitochondrial matrixOne of 2 routes

Two steps

beta-carbolineReach from here →
1. transport of citrulline and tryptophan (cytosol to extracellular)
2. beta-carboline hydrolysis
Catalysed by SLC7A9, SLC3A1, SLC7A6extracellular space, cytosol
CHEBI:1146900Reach from here →
1. transport of citrulline and lysine (cytosol to extracellular)
2. Acetylation of Lysine
Catalysed by SLC7A5, SLC7A6extracellular space, cytosol, mitochondrial matrixOne of 39 routes
N(omega)-methyl-L-arginine