(S)-3-amino-2-methylpropanoate

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

58 compounds within 3 steps: 2 in 1, 6 in 2, 50 in 3

One step

2-methyl-3-oxopropanoic acidReach from here →
1. L-3-amino-isobutanoate:2-oxoglutarate aminotransferase
Catalysed by ABATmitochondrial matrix
2-methyl-3-oxopropanoateReach from here →
1. (S)-3-amino-2-methylpropanoate + 2-oxoglutarate = 2-methyl-3-oxopropanoate + L-glutamate
Catalysed by ABAT

Two steps

3-hydroxy-2-methylpropanoateReach from here →
1. (S)-3-amino-2-methylpropanoate + 2-oxoglutarate = 2-methyl-3-oxopropanoate + L-glutamate
2. 3-hydroxy-2-methylpropanoate + NAD(+) = 2-methyl-3-oxopropanoate + NADH + H(+)
Catalysed by ABAT, HIBADH
pyruvateReach from here →
1. L-3-amino-isobutanoate:2-oxoglutarate aminotransferase
2. (R)-3-Amino-2-methylpropanoate:pyruvate aminotransferase
Catalysed by ABAT, AGXT2mitochondrial matrix
propionyl-CoAReach from here →

Three steps

(S)-carnitineReach from here →
Catalysed by ABAT, ALDH6A1mitochondrial matrix, cytosolOne of 2 routes
CHEBI:1146900Reach from here →
Catalysed by ABAT, ALDH6A1

Catalysed by ABAT, ALDH6A1mitochondrial matrix

(R)-3-aminoisobutyric acidReach from here →

Catalysed by ABAT, AGXT2mitochondrial matrixOne of 2 routes

(R)-methylmalonyl-CoAReach from here →

Catalysed by ABAT, ALDH6A1mitochondrial matrix

propanoyl-CoAReach from here →

Catalysed by ABAT, ALDH6A1

, ACOT7

mitochondrial matrix, cytosol

One of 13 routes

2-hydroxybutyric acidReach from here →

Catalysed by ABAT, AGXT2, SLC16A4, SLC16A5 and 4 moremitochondrial matrix, extracellular space, cytosolOne of 2 routes

acetoacetateReach from here →

Catalysed by ABAT, AGXT2mitochondrial matrix, cytosolOne of 4 routes

acetylpyruvateReach from here →

Catalysed by ABAT, AGXT2, FAHD1mitochondrial matrix

all-trans-retinoic acidReach from here →

Catalysed by ABAT, AGXT2, SLC16A4, SLC16A5 and 4 moremitochondrial matrix, extracellular space, cytosolOne of 2 routes

CHEBI:15380Reach from here →

Catalysed by ABAT, ALDH6A1, MMUTmitochondrial matrix

(S)-malateReach from here →

Catalysed by ABAT, AGXT2, ME2mitochondrial matrixOne of 2 routes

oxaloacetateReach from here →

Catalysed by ABAT, AGXT2, PCmitochondrial matrixOne of 3 routes

(S)-lactateReach from here →

Catalysed by ABAT, AGXT2, LDHA, LDHB and 3 moremitochondrial matrix

2-oxobutanoateReach from here →

Catalysed by ABAT, AGXT2mitochondrial matrix

2-oxoglutaramateReach from here →

Catalysed by ABAT, AGXT2, KYAT1mitochondrial matrix, cytosolOne of 2 routes

3-fumarylpyruvateReach from here →

Catalysed by ABAT, AGXT2, FAHD1mitochondrial matrix

(R)-3-hydroxybutyric acidReach from here →

Catalysed by ABAT, AGXT2, SLC16A4, SLC16A5 and 4 moremitochondrial matrix, extracellular space, cytosolOne of 2 routes

3-hydroxypyruvateReach from here →

Catalysed by ABAT, AGXT2, AGXTmitochondrial matrix

propanoyl-4'-phosphopantetheineReach from here →

Catalysed by ABAT, ALDH6A1, NUDT19, NUDT7 and 1 more

propanoateReach from here →

Catalysed by ABAT, ALDH6A1, ACOT8, ACAA2 and 1 more

aceneuramateReach from here →

Catalysed by ABAT, AGXT2, NPLmitochondrial matrix

5'-deoxyadenosineReach from here →

Catalysed by ABAT, AGXT2, TYW1B, TYW1mitochondrial matrix

dTDPReach from here →

Catalysed by ABAT, AGXT2, PKM, PKLRmitochondrial matrix, cytosol

5-(3,3-dimethylguanidino)-2-oxopentanoateReach from here →

Catalysed by ABAT, AGXT2mitochondrial matrix

5-(3,3'-dimethylguanidino)-2-oxopentanoateReach from here →

Catalysed by ABAT, AGXT2mitochondrial matrix

5-(3-methylguanidino)-2-oxopentanoateReach from here →

Catalysed by ABAT, AGXT2mitochondrial matrix

acetateReach from here →

Catalysed by ABAT, AGXT2, SLC16A4, SLC16A5 and 3 moremitochondrial matrix, extracellular space, cytosolOne of 2 routes

formic acidReach from here →

Catalysed by ABAT, AGXT2, SLC16A4, SLC16A5 and 3 moremitochondrial matrix, extracellular space, cytosolOne of 2 routes

propionic acidReach from here →

Catalysed by ABAT, AGXT2, SLC16A4, SLC16A5 and 4 moremitochondrial matrix, extracellular space, cytosolOne of 5 routes

butyric acidReach from here →

Catalysed by ABAT, AGXT2, SLC16A4, SLC16A5 and 4 moremitochondrial matrix, extracellular space, cytosolOne of 2 routes

3-hydroxypyruvic acidReach from here →

Catalysed by ABAT, AGXT2, AGXTmitochondrial matrix, cytosolOne of 2 routes

3-oxopropanoateReach from here →

Catalysed by ABAT, AGXT2mitochondrial matrix

D-serineReach from here →

Catalysed by ABAT, AGXT2, SRRmitochondrial matrix

(R)-lactic acidReach from here →

Catalysed by ABAT, AGXT2, LDHDmitochondrial matrix, cytosol

(S)-lactic acidReach from here →

Catalysed by ABAT, AGXT2, LDHB, LDHAL6Bmitochondrial matrixOne of 5 routes

2-iminopropanoateReach from here →

Catalysed by ABAT, AGXT2, RIDAmitochondrial matrix

phosphoenolpyruvic acidReach from here →

Catalysed by ABAT, AGXT2, PKM, PKLRmitochondrial matrix, cytosol

N-acetyl-beta-neuraminic acidReach from here →

Catalysed by ABAT, AGXT2, NPLmitochondrial matrix, cytosol

O-propanoyl-(R)-carnitineReach from here →

Catalysed by ABAT, ALDH6A1, CRAT

a 3-acylpyruvateReach from here →

Catalysed by ABAT, AGXT2, FAHD1mitochondrial matrix

succinyl-CoAReach from here →

Catalysed by ABAT, ALDH6A1, MMUTmitochondrial matrix

(S)-methylmalonyl-CoAReach from here →

Catalysed by ABAT, ALDH6A1, PCCA, PCCBmitochondrial matrixOne of 2 routes

2-methyl-3-oxobutanoyl-CoAReach from here →

Catalysed by ABAT, ALDH6A1, ACAT1

acryloyl-CoAReach from here →

Catalysed by ABAT, ALDH6A1, ACADS, ACADSBmitochondrial matrixOne of 2 routes

2-oxo-3-sulfanylpropanoateReach from here →

Catalysed by ABAT, AGXT2, MPSTmitochondrial matrix