acetoacetate

Structure

Identity from ChEBI, geometry from PubChem. Not evidence.

What it touches on the way

What the reference databases state

• acetoacetate⇌acetoacetate

  Reaction pageReversibleBalancedEC 2.3.1.16cytosol, peroxisome

  Human-GEM MAR00056CC BY 4.0Reference data

• acetoacetate+ATP+CHEBI:1146900→CHEBI:15345+AMP+diphosphate(3-)

  Catalysed by AACS

  Reaction pageLeft to rightBalancedEC 6.2.1.16cytosol

  Human-GEM MAR01436CC BY 4.0Reference data

• CHEBI:15467→acetoacetate+CHEBI:15351

  Catalysed by HMGCL

  Reaction pageLeft to rightBalancedEC 4.1.3.4peroxisome

  Human-GEM MAR01449CC BY 4.0Reference data

• acetoacetate+ATP+CHEBI:1146900→CHEBI:15345+AMP+diphosphate(3-)

  Catalysed by AACS

  Reaction pageLeft to rightBalancedEC 6.2.1.16mitochondrial matrix

  Human-GEM MAR01576CC BY 4.0Reference data

• CHEBI:15467→acetoacetate+CHEBI:15351

  Catalysed by HMGCL or HMGCLL1

  Reaction pageLeft to rightBalancedEC 4.1.3.4mitochondrial matrix

  Human-GEM MAR01577CC BY 4.0Reference data

• acetoacetate+CHEBI:15380→CHEBI:15345+succinate(2-)

  Catalysed by OXCT1 or OXCT2

  Reaction pageLeft to rightBalancedEC 2.8.3.5mitochondrial matrix

  Human-GEM MAR03787CC BY 4.0Reference data

• (R)-3-hydroxybutyric acid+NAD(+)⇌acetoacetate+proton+NADH(2-)

  Catalysed by BDH1 or BDH2

  Reaction pageReversibleBalancedEC 1.1.1.30mitochondrial matrix

  Human-GEM MAR04461CC BY 4.0Reference data

• acetoacetate+proton→acetone+carbon dioxide

  Reaction pageLeft to rightBalancedEC 4.1.1.4mitochondrial matrix

  Human-GEM MAR04464CC BY 4.0Reference data

• acetoacetate+proton→acetoacetate+proton

  Transported by SLC16A8 or SLC16A6 or SLC16A7 or SLC16A1 or SLC16A4 or SLC16A5

  Reaction pageLeft to rightBalancedextracellular space, cytosol

  Human-GEM MAR04976CC BY 4.0Reference data

• acetoacetate+proton→acetoacetate+proton

  Transported by SLC16A1

  Reaction pageLeft to rightBalancedcytosol, mitochondrial matrix

  Human-GEM MAR04977CC BY 4.0Reference data

• acetoacetate+pyruvate⇌acetoacetate+pyruvate

  Reaction pageReversibleBalancedcytosol, mitochondrial matrix

  Human-GEM MAR05426CC BY 4.0Reference data

• acetoacetate+pyruvate⇌acetoacetate+pyruvate

  Transported by SLC16A7 or SLC16A3 or SLC16A1 or SLC16A4 or SLC16A5

  Reaction pageReversibleBalancedcytosol, extracellular space

  Human-GEM MAR06000CC BY 4.0Reference data

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Where it reaches

9 systems, 17 regions, 34 tissues, 35 transporter routes — routes, not measurements: transporters known to carry acetoacetate are expressed there, and no source reports it arriving.

Resolves to: acetoacetate

Also called

Acetoacetate ion(1-)Butanoic acid, 3-oxo-, ion(1-)

Systematic name

3-oxobutanoate