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Proteins/UNIPROT:P21549
Peroxisomal aminotransferase that catalyzes the transamination of glyoxylate to glycine and contributes to the glyoxylate detoxification. Also catalyzes the transamination between L-serine and pyruvate and contributes to gluconeogenesis from the L-serine metabolism..
Function from UniProtKB (P21549), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
2 rows
28 statements
28 statements · 8 reference databases · Subject: AGXT · Sources: Bgee, Hetionet, Human Protein Atlas, Human-GEM, Reactome, Rhea, UniProt, WikiPathways
6 reactions
pyruvate+L-seryl residueL-alanine+3-hydroxypyruvic acid
Catalysed by AGXT
Reaction pageLeft to rightBalancedEC 2.6.1.51cytosol
Human-GEM MAR04198CC BY 4.0Reference data
pyruvate+L-seryl residueL-alanine+3-hydroxypyruvic acid
Catalysed by AGXT
Reaction pageLeft to rightBalancedEC 2.6.1.51peroxisome
5 names
Resolves to: AGXT
L-alanine+glyoxylic acidglycine+pyruvate
Reaction pageLeft to rightBalancedEC 2.6.1.44mitochondrial matrix
Human-GEM MAR04788CC BY 4.0Reference data
L-alanine+glyoxylic acidglycine+pyruvate
Catalysed by AGXT
Reaction pageLeft to rightBalancedEC 2.6.1.44peroxisome
Human-GEM MAR04791CC BY 4.0Reference data
L-seryl residue+pyruvate3-hydroxypyruvate+L-alanine
Catalysed by AGXT
Reaction pageLeft to rightBalanced
Rhea RHEA:22852CC BY 4.0Reference data
glyoxylate+L-alanineglycine+pyruvate
Reaction pageLeft to rightBalanced
Rhea RHEA:24248CC BY 4.0Reference data