Compound
2-methyl-3-oxopropanoate
The conjugate base of 2-methyl-3-oxopropanoic acid; major species at pH 7.3.
Definition from ChEBI (CHEBI:57700), read 2026-09-23. CC BY 4.0.
Structure
Loading the model…
- Class
- Organic compound, anion
- Formula
- C4H5O3
- Mass
- 101.081 g/mol
- Charge
- -1
- InChIKey
- VOKUMXABRRXHAR-UHFFFAOYSA-M
- SMILES
- CC(C=O)C(=O)[O-]
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
2 entities
2 entities reached.
0 reported hops2 assembled from the scaffold
What the reference databases state
Statements
6 statements
6 statements · 1 reference database · Subject: 2-methyl-3-oxopropanoate · Sources: Rhea
- (S)-3-amino-2-methylpropanoate is converted to 2-methyl-3-oxopropanoateCompoundRhea RHEA:13993Inferred only
- 2-methyl-3-oxopropanoate is converted to 3-hydroxy-2-methylpropanoateCompoundRhea RHEA:17681Inferred only
- 3-hydroxy-2-methylpropanoate is converted to 2-methyl-3-oxopropanoateCompoundRhea RHEA:17681Inferred only
- 2-methyl-3-oxopropanoate is converted to propanoyl-CoACompoundRhea RHEA:20804Inferred only
- 2-methyl-3-oxopropanoate is metabolised by ALDH6A1ProteinRhea RHEA:20804Inferred only
- 2-methyl-3-oxopropanoate is a substrate of HIBADHProteinRhea RHEA:17681Inferred only
Reactions
4 reactions
(S)-3-amino-2-methylpropanoate+2-oxoglutarate(2-)2-methyl-3-oxopropanoate+L-glutamate(1-)
Catalysed by ABAT
Reaction pageLeft to rightBalanced
Rhea RHEA:13993CC BY 4.0Reference data
3-hydroxy-2-methylpropanoate+NAD(1-)2-methyl-3-oxopropanoate+NADH(2-)+hydron
Catalysed by HIBADH
Reaction pageDirection not assertedBalanced
Rhea RHEA:17681CC BY 4.0Reference data
(R)-3-amino-2-methylpropanoate+pyruvate2-methyl-3-oxopropanoate+L-alanine
Catalysed by AGXT2
Reaction pageLeft to rightBalanced
Rhea RHEA:18393CC BY 4.0Reference data
2-methyl-3-oxopropanoate+NAD(1-)+coenzyme A(4-)+waterpropanoyl-CoA+hydrogencarbonate+NADH(2-)+hydron
Catalysed by ALDH6A1
Reaction pageLeft to rightBalanced
Rhea RHEA:20804CC BY 4.0Reference data