dTDP

1. pyruvate kinase (dTDP)

Catalysed by PKM, PKLRcytosol

1. nucleoside-diphosphate kinase (dADP)

Catalysed by NME4, NME6, NME1, NME2 and 2 morecytosolOne of 3 routes

1. deoxythymidylate kinase (dADP)

Catalysed by DTYMKmitochondrial matrixOne of 2 routes

1. DTTP Nucleotidohydrolase

Catalysed by ENTPD3, ENTPD1, ENTPD8extracellular spaceOne of 10 routes

1. DTDP Diphosphohydrolase

Catalysed by ENTPD3, ENTPD1, ENTPD8extracellular spaceOne of 5 routes

1. pyruvate kinase (dTDP)
2. transport of 2-hydroxybutyrate and pyruvate (cytosol to extracellular)

Catalysed by PKM, PKLR, SLC16A4, SLC16A5 and 4 morecytosol, extracellular spaceOne of 2 routes

1. pyruvate kinase (dTDP)
2. transport of acetoacetate and pyruvate (cytosol to mitochondria)

Catalysed by PKM, PKLRcytosol, mitochondrial matrixOne of 4 routes