Compound
(S)-lactic acid
A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
Structure
Loading the model…
- Class
- Organic compound
- Formula
- C3H6O3
- Mass
- 90.078 g/mol
- Charge
- 0
- InChIKey
- JVTAAEKCZFNVCJ-REOHCLBHSA-N
- SMILES
- C[C@H](O)C(=O)O
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
9 entities
9 entities reached.
0 reported hops9 assembled from the scaffold
- SLC16A1ProteinUNIPROT:P53985transported byInferred only325 paths25 endpoints
- LDHAProteinUNIPROT:P00338substrate ofInferred only100 paths50 endpoints
- LDHBProteinUNIPROT:P07195substrate ofInferred only69 paths23 endpoints
- SLC16A7ProteinUNIPROT:O60669transported byInferred only66 paths6 endpoints
- SLC16A3ProteinUNIPROT:O15427transported byInferred only63 paths7 endpoints
- SLC16A8ProteinUNIPROT:O95907transported byInferred only11 paths1 endpoint
- LDHAL6BProteinUNIPROT:Q9BYZ2substrate ofInferred only10 paths5 endpoints
- LDHCProteinUNIPROT:P07864substrate ofInferred only9 paths9 endpoints
- LDHAL6AProteinUNIPROT:Q6ZMR3substrate ofInferred only3 paths3 endpoints
What the reference databases state
Chemical structure
- (R)-lactic acid is the enantiomer of (S)-lactic acidCompoundChEBI CHEBI:42111Inferred only
Statements
86 statements
86 statements · 2 reference databases · Subject: (S)-lactic acid · Sources: ChEBI, Human-GEM
- (S)-lactic acid is converted to pyruvateCompoundHuman-GEM MAR04281Inferred only
- pyruvate is converted to (S)-lactic acidCompoundHuman-GEM MAR04388Inferred only
- pyruvate is converted to (S)-lactic acidCompoundHuman-GEM MAR04281Inferred only
- (S)-lactic acid is converted to pyruvateCompoundHuman-GEM MAR04388Inferred only
- (S)-lactic acid is converted to pyruvateCompoundHuman-GEM MAR04280Inferred only
- pyruvate is converted to (S)-lactic acidCompoundHuman-GEM MAR04280Inferred only
- rac-lactic acid is converted to (S)-lactic acidCompoundChEBI CHEBI:28358Inferred only
- (S)-lactic acid is a substrate of CYB5D1ProteinHuman-GEM MAR08514Inferred only
- (S)-lactic acid is a substrate of LDHAProteinHuman-GEM MAR04388Inferred only
- (S)-lactic acid is a substrate of LDHAProteinHuman-GEM MAR04281Inferred only
- (S)-lactic acid is a substrate of LDHAL6AProteinHuman-GEM MAR04388Inferred only
- (S)-lactic acid is a substrate of LDHAL6BProteinHuman-GEM MAR04388Inferred only
Show the remaining 74
- (S)-lactic acid is a substrate of LDHAL6BProteinHuman-GEM MAR04280Inferred only
- (S)-lactic acid is a substrate of LDHBProteinHuman-GEM MAR04280Inferred only
- (S)-lactic acid is a substrate of LDHBProteinHuman-GEM MAR04281Inferred only
- (S)-lactic acid is a substrate of LDHBProteinHuman-GEM MAR04388Inferred only
- (S)-lactic acid is a substrate of LDHCProteinHuman-GEM MAR04388Inferred only
- (S)-lactic acid is transported by SLC16A1ProteinHuman-GEM MAR06011Inferred only
- (S)-lactic acid is transported by SLC16A1ProteinHuman-GEM MAR06026Inferred only
- (S)-lactic acid is transported by SLC16A1ProteinHuman-GEM MAR06038Inferred only
- (S)-lactic acid is transported by SLC16A1ProteinHuman-GEM MAR06033Inferred only
- (S)-lactic acid is transported by SLC16A1ProteinHuman-GEM MAR06004Inferred only
- (S)-lactic acid is transported by SLC16A1ProteinHuman-GEM MAR06050Inferred only
- (S)-lactic acid is transported by SLC16A1ProteinHuman-GEM MAR06018Inferred only
- (S)-lactic acid is transported by SLC16A1ProteinHuman-GEM MAR06049Inferred only
- (S)-lactic acid is transported by SLC16A1ProteinHuman-GEM MAR06048Inferred only
- (S)-lactic acid is transported by SLC16A1ProteinHuman-GEM MAR05998Inferred only
- (S)-lactic acid is transported by SLC16A1ProteinHuman-GEM MAR03007Inferred only
- (S)-lactic acid is transported by SLC16A1ProteinHuman-GEM MAR05411Inferred only
- (S)-lactic acid is transported by SLC16A1ProteinHuman-GEM MAR06042Inferred only
- (S)-lactic acid is transported by SLC16A3ProteinHuman-GEM MAR06038Inferred only
- (S)-lactic acid is transported by SLC16A3ProteinHuman-GEM MAR06011Inferred only
- (S)-lactic acid is transported by SLC16A3ProteinHuman-GEM MAR06049Inferred only
- (S)-lactic acid is transported by SLC16A3ProteinHuman-GEM MAR06042Inferred only
- (S)-lactic acid is transported by SLC16A3ProteinHuman-GEM MAR06033Inferred only
- (S)-lactic acid is transported by SLC16A3ProteinHuman-GEM MAR06048Inferred only
- (S)-lactic acid is transported by SLC16A3ProteinHuman-GEM MAR06026Inferred only
- (S)-lactic acid is transported by SLC16A3ProteinHuman-GEM MAR05998Inferred only
- (S)-lactic acid is transported by SLC16A3ProteinHuman-GEM MAR06018Inferred only
- (S)-lactic acid is transported by SLC16A4ProteinHuman-GEM MAR06038Inferred only
- (S)-lactic acid is transported by SLC16A4ProteinHuman-GEM MAR06042Inferred only
- (S)-lactic acid is transported by SLC16A4ProteinHuman-GEM MAR06011Inferred only
- (S)-lactic acid is transported by SLC16A4ProteinHuman-GEM MAR06018Inferred only
- (S)-lactic acid is transported by SLC16A4ProteinHuman-GEM MAR06050Inferred only
- (S)-lactic acid is transported by SLC16A4ProteinHuman-GEM MAR06048Inferred only
- (S)-lactic acid is transported by SLC16A4ProteinHuman-GEM MAR06033Inferred only
- (S)-lactic acid is transported by SLC16A4ProteinHuman-GEM MAR06004Inferred only
- (S)-lactic acid is transported by SLC16A4ProteinHuman-GEM MAR05998Inferred only
- (S)-lactic acid is transported by SLC16A4ProteinHuman-GEM MAR06049Inferred only
- (S)-lactic acid is transported by SLC16A4ProteinHuman-GEM MAR06026Inferred only
- (S)-lactic acid is transported by SLC16A5ProteinHuman-GEM MAR06026Inferred only
- (S)-lactic acid is transported by SLC16A5ProteinHuman-GEM MAR06048Inferred only
- (S)-lactic acid is transported by SLC16A5ProteinHuman-GEM MAR06049Inferred only
- (S)-lactic acid is transported by SLC16A5ProteinHuman-GEM MAR05998Inferred only
- (S)-lactic acid is transported by SLC16A5ProteinHuman-GEM MAR06004Inferred only
- (S)-lactic acid is transported by SLC16A5ProteinHuman-GEM MAR06011Inferred only
- (S)-lactic acid is transported by SLC16A5ProteinHuman-GEM MAR06018Inferred only
- (S)-lactic acid is transported by SLC16A5ProteinHuman-GEM MAR06033Inferred only
- (S)-lactic acid is transported by SLC16A5ProteinHuman-GEM MAR06038Inferred only
- (S)-lactic acid is transported by SLC16A5ProteinHuman-GEM MAR06042Inferred only
- (S)-lactic acid is transported by SLC16A5ProteinHuman-GEM MAR06050Inferred only
- (S)-lactic acid is transported by SLC16A6ProteinHuman-GEM MAR06011Inferred only
- (S)-lactic acid is transported by SLC16A7ProteinHuman-GEM MAR05998Inferred only
- (S)-lactic acid is transported by SLC16A7ProteinHuman-GEM MAR06004Inferred only
- (S)-lactic acid is transported by SLC16A7ProteinHuman-GEM MAR06026Inferred only
- (S)-lactic acid is transported by SLC16A7ProteinHuman-GEM MAR06033Inferred only
- (S)-lactic acid is transported by SLC16A7ProteinHuman-GEM MAR06038Inferred only
- (S)-lactic acid is transported by SLC16A7ProteinHuman-GEM MAR06042Inferred only
- (S)-lactic acid is transported by SLC16A7ProteinHuman-GEM MAR06048Inferred only
- (S)-lactic acid is transported by SLC16A7ProteinHuman-GEM MAR06050Inferred only
- (S)-lactic acid is transported by SLC16A7ProteinHuman-GEM MAR06049Inferred only
- (S)-lactic acid is transported by SLC16A7ProteinHuman-GEM MAR06011Inferred only
- (S)-lactic acid is transported by SLC16A7ProteinHuman-GEM MAR06018Inferred only
- (S)-lactic acid is transported by SLC16A8ProteinHuman-GEM MAR06049Inferred only
- (S)-lactic acid is transported by SLC16A8ProteinHuman-GEM MAR06038Inferred only
- (S)-lactic acid is transported by SLC16A8ProteinHuman-GEM MAR06033Inferred only
- (S)-lactic acid is transported by SLC16A8ProteinHuman-GEM MAR06042Inferred only
- (S)-lactic acid is transported by SLC16A8ProteinHuman-GEM MAR06018Inferred only
- (S)-lactic acid is transported by SLC16A8ProteinHuman-GEM MAR05998Inferred only
- (S)-lactic acid is transported by SLC16A8ProteinHuman-GEM MAR06048Inferred only
- (S)-lactic acid is transported by SLC16A8ProteinHuman-GEM MAR06004Inferred only
- (S)-lactic acid is transported by SLC16A8ProteinHuman-GEM MAR06050Inferred only
- (S)-lactic acid is transported by SLC16A8ProteinHuman-GEM MAR06011Inferred only
- (S)-lactic acid is transported by SLC16A8ProteinHuman-GEM MAR06026Inferred only
- (S)-lactic acid is transported by SLC22A12ProteinHuman-GEM MAR09622Inferred only
- (S)-lactic acid is transported by SLC5A8ProteinHuman-GEM MAR08515Inferred only
Reactions
30 reactions
(S)-lactic acid(S)-lactic acid
Reaction pageLeft to rightBalancedEC 2.3.1.21cytosol, mitochondrial matrix
Human-GEM MAR01485CC BY 4.0Reference data
proton+(S)-lactic acidproton+(S)-lactic acid
Transported by SLC16A1
Reaction pageReversibleBalancedcytosol, peroxisome
Human-GEM MAR03007CC BY 4.0Reference data
proton+NADH(2-)+pyruvate(S)-lactic acid+NAD(+)
Reaction pageReversibleBalancedEC 1.1.1.27mitochondrial matrix
Human-GEM MAR04280CC BY 4.0Reference data
proton+NADH(2-)+pyruvate(S)-lactic acid+NAD(+)
Reaction pageReversibleBalancedEC 1.1.1.27peroxisome
Human-GEM MAR04281CC BY 4.0Reference data
proton+NADH(2-)+pyruvate(S)-lactic acid+NAD(+)
Catalysed by LDHB or LDHA or LDHC or LDHAL6A or LDHAL6B
Reaction pageReversibleBalancedEC 1.1.1.27cytosol
Human-GEM MAR04388CC BY 4.0Reference data
proton+(S)-lactic acidproton+(S)-lactic acid
Transported by SLC16A1
Reaction pageReversibleBalancedcytosol, mitochondrial matrix
Human-GEM MAR05411CC BY 4.0Reference data
proton+(S)-lactic acidproton+(S)-lactic acid
Transported by SLC16A8 or SLC16A7 or SLC16A3 or SLC16A1 or SLC16A4 or SLC16A5
Reaction pageReversibleBalancedextracellular space, cytosol
Human-GEM MAR05998CC BY 4.0Reference data
acetoacetate+(S)-lactic acidacetoacetate+(S)-lactic acid
Transported by SLC16A8 or SLC16A7 or SLC16A1 or SLC16A4 or SLC16A5
Reaction pageReversibleBalancedextracellular space, cytosol
Human-GEM MAR06004CC BY 4.0Reference data
2-hydroxybutyric acid+(S)-lactic acid2-hydroxybutyric acid+(S)-lactic acid
Transported by SLC16A8 or SLC16A6 or SLC16A7 or SLC16A3 or SLC16A1 or SLC16A4 or SLC16A5
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR06011CC BY 4.0Reference data
(S)-lactic acid+pyruvate(S)-lactic acid+pyruvate
Transported by SLC16A8 or SLC16A7 or SLC16A3 or SLC16A1 or SLC16A4 or SLC16A5
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR06018CC BY 4.0Reference data
2-oxoglutarate(2-)+(S)-lactic acid2-oxoglutarate(2-)+(S)-lactic acid
Transported by SLC16A8 or SLC16A7 or SLC16A3 or SLC16A1 or SLC16A4 or SLC16A5
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR06026CC BY 4.0Reference data
acetate+(S)-lactic acidacetate+(S)-lactic acid
Transported by SLC16A8 or SLC16A7 or SLC16A3 or SLC16A1 or SLC16A4 or SLC16A5
Reaction pageReversibleBalancedextracellular space, cytosol
Human-GEM MAR06033CC BY 4.0Reference data
Where it reaches
9 systems, 17 regions, 34 tissues, 34 transporter routes — routes, not measurements: transporters known to carry (S)-lactic acid are expressed there, and no source reports it arriving.
Loading the model…
Other names
9 names
Resolves to: (S)-lactic acid
- Also called
- (+)-lactic acid(S)-(+)-lactic acid(S)-2-hydroxypropanoic acid(S)-2-hydroxypropionic acidL-(+)-alpha-hydroxypropionic acidL-(+)-lactic acidL-(+)-α-hydroxypropionic acidL-Lactic acid
- Systematic name
- (2S)-2-hydroxypropanoic acid