a 3-acylpyruvate

1. a 3-acylpyruvate + H2O = a carboxylate + pyruvate + H(+)

Catalysed by FAHD1

1. a 3-acylpyruvate + H2O = a carboxylate + pyruvate + H(+)

Catalysed by FAHD1

1. a 3-acylpyruvate + H2O = a carboxylate + pyruvate + H(+)
2. transport of 2-hydroxybutyrate and pyruvate (cytosol to extracellular)

Catalysed by FAHD1, SLC16A4, SLC16A5, SLC16A3 and 3 moreextracellular space, cytosolOne of 2 routes

1. a 3-acylpyruvate + H2O = a carboxylate + pyruvate + H(+)
2. transport of acetoacetate and pyruvate (cytosol to mitochondria)

Catalysed by FAHD1mitochondrial matrix, cytosolOne of 4 routes

1. a 3-acylpyruvate + H2O = a carboxylate + pyruvate + H(+)
2. transport of acetoacetate and pyruvate (cytosol to mitochondria)
3. (S)-3-hydroxybutanoate + 2-oxoglutarate = (R)-2-hydroxyglutarate + acetoacetate

Catalysed by FAHD1, ADHFE1mitochondrial matrix, cytosol