Compound
acryloyl-CoA
Tetraanion of acryloyl-CoA arising from deprotonation of phosphate and diphosphate functions.
Definition from ChEBI (CHEBI:57367), read 2026-09-23. CC BY 4.0.
Structure
No three-dimensional record for this entry.
- Class
- Organic compound, anion
- Formula
- C24H34N7O17P3S
- Mass
- 817.557 g/mol
- Charge
- -4
- InChIKey
- POODSGUMUCVRTR-IEXPHMLFSA-J
- SMILES
- C=CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(=O)([O-])OP(=O)([O-])OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1OP(=O)([O-])[O-]
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
2 entities
2 entities reached.
0 reported hops2 assembled from the scaffold
What the reference databases state
Statements
10 statements
10 statements · 2 reference databases · Subject: acryloyl-CoA · Sources: Human-GEM, Rhea
- (S)-methylmalonyl-CoA is converted to acryloyl-CoACompoundRhea RHEA:60252Inferred only
- acryloyl-CoA is converted to (S)-methylmalonyl-CoACompoundRhea RHEA:60252Inferred only
- acryloyl-CoA is converted to propanoyl-CoACompoundRhea RHEA:26454Inferred only
- propanoyl-CoA is converted to acryloyl-CoACompoundRhea RHEA:26454Inferred only
- propanoyl-CoA is converted to acryloyl-CoACompoundRhea RHEA:34471Inferred only
- acryloyl-CoA is converted to propanoyl-CoACompoundRhea RHEA:34471Inferred only
- propionyl-CoA is converted to acryloyl-CoACompoundHuman-GEM MAR03212Inferred only
- acryloyl-CoA is a substrate of ECHS1ProteinRhea RHEA:26518Inferred only
- acryloyl-CoA is a substrate of ECHS1ProteinHuman-GEM MAR04735Inferred only
- acryloyl-CoA is a substrate of EHHADHProteinHuman-GEM MAR01655Inferred only
Reactions
10 reactions
acryloyl-CoA+waterMAM00799x
Catalysed by EHHADH
Reaction pageLeft to rightBalancedEC 4.2.1.17peroxisome
Human-GEM MAR01655CC BY 4.0Reference data
FAD+propionyl-CoAacryloyl-CoA+FADH2
Reaction pageLeft to rightBalancedEC 1.3.8.7, 1.3.8.8, 1.3.8.9mitochondrial matrix
Human-GEM MAR03212CC BY 4.0Reference data
acryloyl-CoA+waterMAM00799m
Catalysed by ECHS1
Reaction pageReversibleBalancedEC 4.2.1.17mitochondrial matrix
Human-GEM MAR04735CC BY 4.0Reference data
CHEBI:57362acryloyl-CoA+ammonium
Reaction pageDirection not assertedBalanced
Rhea RHEA:12416CC BY 4.0Reference data
propanoyl-CoA+NADP(3-)acryloyl-CoA+NADPH(4-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:26454CC BY 4.0Reference data
CHEBI:58528acryloyl-CoA+water
Catalysed by ECHS1
Reaction pageRight to leftBalanced
Rhea RHEA:26518CC BY 4.0Reference data
propanoyl-CoA+oxidized [electron-transfer flavoprotein]+hydronacryloyl-CoA+reduced [electron-transfer flavoprotein]
Catalysed by ACAD8
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:31287CC BY 4.0Reference data
propanoyl-CoA+NAD(1-)acryloyl-CoA+NADH(2-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:34471CC BY 4.0Reference data
CHEBI:70980acryloyl-CoA+water
Reaction pageDirection not assertedBalanced
Rhea RHEA:34691CC BY 4.0Reference data
(S)-methylmalonyl-CoA+NADP(3-)acryloyl-CoA+carbon dioxide+NADPH(4-)
Reaction pageDirection not assertedBalanced
Rhea RHEA:60252CC BY 4.0Reference data
Other names
1 name
Resolves to: acryloyl-CoA
- Systematic name
- 3'-phosphonatoadenosine 5'-(3-{(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-[(3-oxo-3-{[2-(prop-2-enoylsulfanyl)ethyl]amino}propyl)amino]butyl} diphosphate)