succinyl-CoA

1. succinyl-CoA + H2O = succinyl-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)

Catalysed by NUDT19, NUDT7, NUDT8

1. succinyl-CoA + glycine + H(+) = 5-aminolevulinate + CO2 + CoA

Catalysed by ALAS1, ALAS2

1. 3-hydroxy-3-methylglutarate + succinyl-CoA = (3S)-3-hydroxy-3-methylglutaryl-CoA + succinate

Catalysed by SUGCT

1. acetoacetate + succinyl-CoA = acetoacetyl-CoA + succinate

Catalysed by OXCT1

1. glutarate + succinyl-CoA = glutaryl-CoA + succinate

Catalysed by SUGCT

1. itaconate + succinyl-CoA = itaconyl-CoA + succinate

Catalysed by SUGCT

1. a 3-oxo acid + succinyl-CoA = a 3-oxoacyl-CoA + succinate

Catalysed by OXCT1, OXCT2

1. itaconate + succinyl-CoA = itaconyl-CoA + succinate
2. Itaconate:CoA ligase (GDP-forming)

Catalysed by SUGCT, SUCLG1, SUCLG2, SUCLA2mitochondrial matrixOne of 3 routes

1. 3-hydroxy-3-methylglutarate + succinyl-CoA = (3S)-3-hydroxy-3-methylglutaryl-CoA + succinate
2. (3S)-3-hydroxy-3-methylglutaryl-CoA = acetoacetate + acetyl-CoA

Catalysed by SUGCT, HMGCL, HMGCLL1One of 2 routes

1. 3-hydroxy-3-methylglutarate + succinyl-CoA = (3S)-3-hydroxy-3-methylglutaryl-CoA + succinate
2. (3S)-3-hydroxy-3-methylglutaryl-CoA = acetoacetate + acetyl-CoA
3. (S)-3-hydroxybutanoate + 2-oxoglutarate = (R)-2-hydroxyglutarate + acetoacetate

Catalysed by SUGCT, HMGCL, HMGCLL1, ADHFE1

1. itaconate + succinyl-CoA = itaconyl-CoA + succinate
2. Itaconate:CoA ligase (GDP-forming)
3. Carnitine O-Palmitoyltransferase

Catalysed by and 3 more