Loading the page.
Proteins/UNIPROT:P11498
Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. Catalyzes in a tissue specific manner, the initial reactions of glucose (liver, kidney) and lipid (adipose tissue, liver, brain) synthesis from pyruvate..
Function from UniProtKB (P11498), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
4 rows
183 statements
183 statements · 9 reference databases · Subject: PC · Sources: Bgee, gene ontology, Hetionet, Human Protein Atlas, Human-GEM, Reactome, Rhea, UniProt, WikiPathways
2 reactions
ATP+hydrogencarbonate+pyruvateADP+proton+oxaloacetate+phosphate(3-)
Catalysed by PC
Reaction pageLeft to rightBalancedEC 6.4.1.1mitochondrial matrix
Human-GEM MAR04143CC BY 4.0Reference data
2 names
Resolves to: PC
Catalysed by PC
Reaction pageLeft to rightBalanced
Rhea RHEA:20844CC BY 4.0Reference data