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Proteins/UNIPROT:P07195
Interconverts simultaneously and stereospecifically pyruvate and lactate with concomitant interconversion of NADH and NAD(+)..
Function from UniProtKB (P07195), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
784 statements
784 statements · 7 reference databases · Subject: LDHB · Sources: Bgee, Hetionet, Human Protein Atlas, Human-GEM, Reactome, Rhea, WikiPathways · Rows fetched: 300
10 reactions
3proton+23-hydroxypyruvic acid+NADH(2-)NAD(+)+2MAM03620c
Catalysed by LDHB or LDHA or LDHC or LDHAL6A or LDHD or LDHAL6B
Reaction pageLeft to rightUnbalancedEC 1.1.1.27cytosol
Human-GEM MAR01453CC BY 4.0Reference data
4 names
Resolves to: LDHB
Reaction pageReversibleBalancedEC 1.1.1.27mitochondrial matrix
Human-GEM MAR04280CC BY 4.0Reference data
proton+NADH(2-)+pyruvate(S)-lactic acid+NAD(+)
Reaction pageReversibleBalancedEC 1.1.1.27peroxisome
Human-GEM MAR04281CC BY 4.0Reference data
proton+NADH(2-)+pyruvate(S)-lactic acid+NAD(+)
Catalysed by LDHB or LDHA or LDHC or LDHAL6A or LDHAL6B
Reaction pageReversibleBalancedEC 1.1.1.27cytosol
Human-GEM MAR04388CC BY 4.0Reference data
2-hydroxybutyric acid+NAD(+)2-oxobutanoate+proton+NADH(2-)
Catalysed by LDHB or LDHC or LDHAL6A or LDHAL6B
Reaction pageReversibleBalancedEC 1.1.1.27cytosol
Human-GEM MAR05351CC BY 4.0Reference data
3-mercaptolactic acid+NAD(+)proton+2-oxo-3-sulfanylpropanoate+NADH(2-)
Catalysed by LDHB or LDHC or LDHAL6A or LDHAL6B
Reaction pageReversibleBalancedEC 1.1.1.27cytosol
Human-GEM MAR06519CC BY 4.0Reference data
glyoxylic acid+water+NAD(+)2proton+NADH(2-)+oxalic acid
Catalysed by LDHB or LDHC or LDHAL6A or LDHD or LDHAL6B
Reaction pageLeft to rightBalancedEC 1.1.1.27cytosol
Human-GEM MAR08780CC BY 4.0Reference data
3-methyl-2-oxovaleric acid+proton+NADH(2-)NAD(+)+MAM03176c
Catalysed by LDHB or LDHA or LDHC or LDHD or LDHAL6B
Reaction pageReversibleBalancedEC 1.1.1.27cytosol
Human-GEM MAR11476CC BY 4.0Reference data
3-methyl-2-oxobutanoate+proton+NADH(2-)NAD(+)+MAM03186c
Catalysed by LDHB or LDHA or LDHC or LDHAL6A or LDHD or LDHAL6B
Reaction pageReversibleBalancedEC 1.1.1.27cytosol
Human-GEM MAR11479CC BY 4.0Reference data
(S)-lactate+NAD(1-)pyruvate+NADH(2-)+hydron
Catalysed by LDHA or LDHB or LDHC or LDHAL6A or LDHAL6B
Reaction pageReversibleBalanced
Rhea RHEA:23444CC BY 4.0Reference data