Compound
(R)-lactic acid
A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
Structure
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- Class
- Organic compound
- Formula
- C3H6O3
- Mass
- 90.078 g/mol
- Charge
- 0
- InChIKey
- JVTAAEKCZFNVCJ-UWTATZPHSA-N
- SMILES
- C[C@@H](O)C(=O)O
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
5 entities
5 entities reached.
0 reported hops5 assembled from the scaffold
- SLC16A1ProteinUNIPROT:P53985transported byInferred only50 paths25 endpoints
- LDHDProteinUNIPROT:Q86WU2substrate ofInferred only10 paths5 endpoints
- SLC16A3ProteinUNIPROT:O15427transported byInferred only7 paths7 endpoints
- SLC16A7ProteinUNIPROT:O60669transported byInferred only6 paths6 endpoints
- SLC16A8ProteinUNIPROT:O95907transported byInferred only1 path1 endpoint
What the reference databases state
Chemical structure
- (R)-lactic acid is the enantiomer of (S)-lactic acidCompoundChEBI CHEBI:42111Inferred only
Statements
15 statements
15 statements · 2 reference databases · Subject: (R)-lactic acid · Sources: ChEBI, Human-GEM
- (R)-lactaldehyde is converted to (R)-lactic acidCompoundHuman-GEM MAR08504Inferred only
- (R)-lactaldehyde is converted to (R)-lactic acidCompoundHuman-GEM MAR01474Inferred only
- pyruvate is converted to (R)-lactic acidCompoundHuman-GEM MAR08512Inferred only
- (R)-lactic acid is converted to pyruvateCompoundHuman-GEM MAR08512Inferred only
- rac-lactic acid is converted to (R)-lactic acidCompoundChEBI CHEBI:28358Inferred only
- (R)-lactic acid is a substrate of LDHDProteinHuman-GEM MAR08512Inferred only
- (R)-lactic acid is a substrate of LDHDProteinHuman-GEM MAR03859Inferred only
- (R)-lactic acid is transported by SLC16A1ProteinHuman-GEM MAR08513Inferred only
- (R)-lactic acid is transported by SLC16A1ProteinHuman-GEM MAR03858Inferred only
- (R)-lactic acid is transported by SLC16A3ProteinHuman-GEM MAR03858Inferred only
- (R)-lactic acid is transported by SLC16A4ProteinHuman-GEM MAR03858Inferred only
- (R)-lactic acid is transported by SLC16A5ProteinHuman-GEM MAR03858Inferred only
Show the remaining 3
- (R)-lactic acid is transported by SLC16A6ProteinHuman-GEM MAR03858Inferred only
- (R)-lactic acid is transported by SLC16A7ProteinHuman-GEM MAR03858Inferred only
- (R)-lactic acid is transported by SLC16A8ProteinHuman-GEM MAR03858Inferred only
Reactions
9 reactions
(R)-lactaldehyde+water+NAD(+)(R)-lactic acid+2proton+NADH(2-)
Catalysed by ALDH18A1 or ALDH2 or ALDH5A1 or ALDH6A1 or ALDH1B1 or ALDH4A1
Reaction pageLeft to rightBalancedEC 1.2.1.3mitochondrial matrix
Human-GEM MAR01474CC BY 4.0Reference data
(R)-S-lactoylglutathione+water(R)-lactic acid+CHEBI:16856+proton
Reaction pageLeft to rightBalancedEC 3.1.2.6cytosol
Human-GEM MAR03857CC BY 4.0Reference data
(R)-lactic acid+proton(R)-lactic acid+proton
Transported by SLC16A8 or SLC16A6 or SLC16A7 or SLC16A3 or SLC16A1 or SLC16A4 or SLC16A5
Reaction pageLeft to rightBalancedextracellular space, cytosol
Human-GEM MAR03858CC BY 4.0Reference data
(R)-lactic acid+2ferricytochrome c2ferrocytochrome c+2proton+pyruvate
Catalysed by LDHD
Reaction pageLeft to rightBalancedEC 1.1.2.4cytosol, mitochondrial matrix
Human-GEM MAR03859CC BY 4.0Reference data
(R)-lactaldehyde+water+NAD(+)(R)-lactic acid+2proton+NADH(2-)
Catalysed by ALDH3A2 or ALDH2 or ALDH1B1 or ALDH9A1 or ALDH7A1
Reaction pageLeft to rightBalancedEC 1.2.1.3cytosol
Human-GEM MAR08504CC BY 4.0Reference data
(R)-S-lactoylglutathione+water(R)-lactic acid+CHEBI:16856+proton
Reaction pageLeft to rightBalancedEC 3.1.2.6mitochondrial matrix
Human-GEM MAR08511CC BY 4.0Reference data
(R)-lactic acid+NAD(+)proton+NADH(2-)+pyruvate
Catalysed by LDHD
Reaction pageReversibleBalancedEC 1.1.2.4cytosol
Human-GEM MAR08512CC BY 4.0Reference data
(R)-lactic acid+proton(R)-lactic acid+proton
Transported by SLC16A1
Reaction pageReversibleBalancedcytosol, mitochondrial matrix
Human-GEM MAR08513CC BY 4.0Reference data
Reaction pageReversibleBalance undeterminableextracellular space
Human-GEM MAR09136CC BY 4.0Reference data
Where it reaches
9 systems, 17 regions, 34 tissues, 34 transporter routes — routes, not measurements: transporters known to carry (R)-lactic acid are expressed there, and no source reports it arriving.
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Other names
9 names
Resolves to: (R)-lactic acid
- Also called
- (-)-lactic acid(−)-lactic acid(R)-(-)-lactic acid(R)-(−)-lactic acidD-2-Hydroxypropanoic acidD-2-Hydroxypropionic acidD-lactic acidLACTIC ACID
- Systematic name
- (2R)-2-hydroxypropanoic acid