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Proteins/UNIPROT:Q02252
Malonate and methylmalonate semialdehyde dehydrogenase involved in the catabolism of valine, thymine, and compounds catabolized by way of beta-alanine, including uracil and cytidine..
Function from UniProtKB (Q02252), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
146 statements
146 statements · 7 reference databases · Subject: ALDH6A1 · Sources: Bgee, Hetionet, Human Protein Atlas, Human-GEM, Reactome, Rhea, WikiPathways
9 reactions
(R)-lactaldehyde+water+NAD(+)(R)-lactic acid+2proton+NADH(2-)
Catalysed by ALDH18A1 or ALDH2 or ALDH5A1 or ALDH6A1 or ALDH1B1 or ALDH4A1
Reaction pageLeft to rightBalancedEC 1.2.1.3mitochondrial matrix
Human-GEM MAR01474CC BY 4.0Reference data
3 names
Resolves to: ALDH6A1
Catalysed by ALDH6A1
Reaction pageLeft to rightBalancedEC 1.2.1.18mitochondrial matrix
Human-GEM MAR03761CC BY 4.0Reference data
CHEBI:1146900+proton+MAM02479m(R)-methylmalonyl-CoA+water
Catalysed by ALDH6A1
Reaction pageLeft to rightBalancedEC 3.1.2.17, 1.2.1.18mitochondrial matrix
Human-GEM MAR03763CC BY 4.0Reference data
2-methyl-3-oxopropanoic acid+CHEBI:1146900+NAD(+)carbon dioxide+NADH(2-)+propionyl-CoA
Catalysed by ALDH6A1
Reaction pageLeft to rightBalancedEC 1.2.1.27mitochondrial matrix
Human-GEM MAR03795CC BY 4.0Reference data
3-oxopropanoic acid+CHEBI:1146900+NAD(+)CHEBI:15351+carbon dioxide+NADH(2-)
Catalysed by ALDH6A1
Reaction pageLeft to rightBalancedEC 1.2.1.18, 1.2.1.27mitochondrial matrix
Human-GEM MAR04282CC BY 4.0Reference data
2-methyl-3-oxopropanoate+NAD(1-)+coenzyme A(4-)+waterpropanoyl-CoA+hydrogencarbonate+NADH(2-)+hydron
Catalysed by ALDH6A1
Reaction pageLeft to rightBalanced
Rhea RHEA:20804CC BY 4.0Reference data
3-oxopropanoate+NAD(1-)+coenzyme A(4-)+waterhydrogencarbonate+acetyl-CoA+NADH(2-)+hydron
Catalysed by ALDH6A1
Reaction pageLeft to rightBalanced
Rhea RHEA:76615CC BY 4.0Reference data
(R)-2-methyl-3-oxopropanoate+NAD(1-)+coenzyme A(4-)+waterpropanoyl-CoA+hydrogencarbonate+NADH(2-)+hydron
Catalysed by ALDH6A1
Reaction pageLeft to rightBalanced
Rhea RHEA:76623CC BY 4.0Reference data
(S)-2-methyl-3-oxopropanoate+NAD(1-)+coenzyme A(4-)+waterpropanoyl-CoA+hydrogencarbonate+NADH(2-)+hydron
Catalysed by ALDH6A1
Reaction pageLeft to rightBalanced
Rhea RHEA:76627CC BY 4.0Reference data