CHEBI:15380

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

558 compounds within 3 steps: 3 in 1, 109 in 2, 446 in 3

One step

CHEBI:1146900Reach from here →
1. 5-aminolevulinate synthase (2-amino-3-oxoadipate)
Catalysed by ALAS1, CPNE7mitochondrial matrixOne of 8 routes
CHEBI:15345Reach from here →
1. succinyl-CoA:acetoacetate CoA-transferase
Catalysed by OXCT1, OXCT2mitochondrial matrix
5-aminolevulinic acidReach from here →
1. succinyl-CoA:glycine C-succinyltransferase (decarboxylating)
Catalysed by ALAS1, ALAS2, CPNE7mitochondrial matrix

Two steps

(S)-carnitineReach from here →
1. 5-aminolevulinate synthase (2-amino-3-oxoadipate)
2. Carnitine O-Palmitoyltransferase
Catalysed by ALAS1, CPNE7, CPT1A, CPT1C and 1 moremitochondrial matrix, cytosolOne of 244 routes
(7Z)-octadecenoyl-CoAReach from here →
1. 5-aminolevulinate synthase (2-amino-3-oxoadipate)
2. carnitine O-palmitoyltransferase ((7Z)-octadecenoyl-CoA)
Catalysed by ALAS1, CPNE7, CPT1A, CPT1C and 1 more

mitochondrial matrix, cytosol

One of 3 routes

cholineReach from here →

Catalysed by ALAS1, CPNE7, CHATmitochondrial matrix, nucleus

CHEBI:15467Reach from here →

Catalysed by OXCT1, OXCT2, HMGCS1mitochondrial matrix, cytosolOne of 3 routes

CHEBI:15477Reach from here →

Catalysed by ALAS1, CPNE7, GLYAT, GLYATL2 and 1 moremitochondrial matrixOne of 2 routes

2-methylcrotonoyl-CoAReach from here →

Catalysed by ALAS1, CPNE7, CPT1A, CPT1Bmitochondrial matrix, cytosolOne of 2 routes

isobutyryl-CoAReach from here →

Catalysed by ALAS1, CPNE7, HADHA, ACAA2 and 1 moremitochondrial matrixOne of 3 routes

3-methylbut-2-enoyl-CoAReach from here →

Catalysed by ALAS1, CPNE7, GLYATmitochondrial matrix

isovaleryl-CoAReach from here →

Catalysed by ALAS1, CPNE7, GLYAT, GLYATL2 and 1 moremitochondrial matrixOne of 3 routes

arachidonoyl-CoAReach from here →

Catalysed by ALAS1, CPNE7, SLC27A2, ACSL4 and 6 moremitochondrial matrix, cytosolOne of 11 routes

CHEBI:15519Reach from here →

Catalysed by ALAS1, CPNE7, ACAA1, SCP2 and 1 moremitochondrial matrix, peroxisomeOne of 2 routes

palmitoyl-CoAReach from here →

Catalysed by ALAS1, CPNE7, SLC27A2, ACSL4 and 6 moremitochondrial matrix, cytosolOne of 11 routes

oleoyl-CoAReach from here →

Catalysed by ALAS1, CPNE7, CPT1A, CPT1C and 1 moremitochondrial matrix, cytosolOne of 11 routes

phenylacetyl-CoAReach from here →

Catalysed by ALAS1, CPNE7mitochondrial matrix, cytosolOne of 3 routes

propionyl-CoAReach from here →

Catalysed by ALAS1, CPNE7, ACSS3, ACSS2 and 1 moremitochondrial matrix, cytosolOne of 43 routes

CHEBI:15650Reach from here →

Catalysed by ALAS1, CPNE7, ZDHHC11B, NAA10 and 30 moremitochondrial matrix, cytosolOne of 2 routes

CHEBI:15727Reach from here →

Catalysed by ALAS1, CPNE7, NAA10mitochondrial matrix, cytosol

CHEBI:15746Reach from here →

Catalysed by ALAS1, CPNE7, SAT1, SAT2mitochondrial matrix, cytosolOne of 2 routes

11-cis-retinolReach from here →

Catalysed by ALAS1, CPNE7, DGAT1, LRAT and 3 moremitochondrial matrix, cytosol

oxaloacetateReach from here →

Catalysed by ALAS1, CPNE7, ACLYmitochondrial matrix, cytosol

anilineReach from here →

Catalysed by ALAS1, CPNE7, NAT2, NAT1mitochondrial matrix, cytosol

CHEBI:17312Reach from here →

Catalysed by ALAS1, CPNE7mitochondrial matrix, cytosolOne of 2 routes

L-cysteineReach from here →

Catalysed by ALAS1, CPNE7, NAGSmitochondrial matrix

(7Z,10Z,13Z)-hexadecatrienoyl-CoAReach from here →

Catalysed by ALAS1, CPNE7, HADHA, ACADVL and 1 moremitochondrial matrix

CHEBI:17927Reach from here →

Catalysed by ALAS1, CPNE7mitochondrial matrix, cytosol

(5Z)-dodecenoyl-CoAReach from here →

Catalysed by ALAS1, CPNE7, HADHA, ACAA2 and 1 moremitochondrial matrixOne of 2 routes

(11Z)-docosenoyl-CoA(4-)Reach from here →

Catalysed by ALAS1, CPNE7, SLC27A2, ACSL4 and 6 moremitochondrial matrix, cytosolOne of 5 routes

(7Z)-tetradecenoyl-CoAReach from here →

Catalysed by ALAS1, CPNE7, SLC27A2, ACSL4 and 6 moremitochondrial matrix, cytosolOne of 8 routes

(4Z,7Z,10Z,13Z)-hexadecatetraenoyl-CoAReach from here →

Catalysed by ALAS1, CPNE7, HADHA, ACADVL and 1 moremitochondrial matrixOne of 3 routes

(7Z,10Z)-hexadecadienoyl-CoAReach from here →

Catalysed by ALAS1, CPNE7, HADHA, ACADVL and 1 moremitochondrial matrix

(4Z,7Z)-decadienoyl-CoAReach from here →

Catalysed by ALAS1, CPNE7, ECHS1, ACAA2 and 1 moremitochondrial matrixOne of 2 routes

(5Z)-octenoyl-CoAReach from here →

Catalysed by ALAS1, CPNE7, ECHS1, ACAA2 and 1 moremitochondrial matrixOne of 2 routes

CHEBI:27540Reach from here →

Catalysed by ALAS1, CPNE7, ACSM4, ACSM1 and 4 moremitochondrial matrix, cytosolOne of 6 routes

elaidic acidReach from here →

Catalysed by ALAS1, CPNE7, SLC27A2, ACSL4 and 6 moremitochondrial matrix, cytosolOne of 5 routes

CHEBI:28701Reach from here →

Catalysed by ALAS1, CPNE7, ACAA1, SCP2 and 1 moremitochondrial matrix, peroxisomeOne of 7 routes

taurineReach from here →

Catalysed by ALAS1, CPNE7, BAATmitochondrial matrix, cytosolOne of 2 routes

glycineReach from here →

Catalysed by ALAS1, CPNE7, GLYAT, GLYATL2 and 1 moremitochondrial matrixOne of 10 routes

(R)-methylmalonyl-CoAReach from here →

Catalysed by ALAS1, CPNE7, ALDH6A1mitochondrial matrixOne of 2 routes

(S)-methylmalonyl-CoAReach from here →

Catalysed by ALAS1, CPNE7mitochondrial matrix

3'-dephospho-CoAReach from here →

Catalysed by ALAS1, CPNE7, ACP2mitochondrial matrix, lysosomeOne of 2 routes

(2E)-dodecenoyl-CoAReach from here →

Catalysed by ALAS1, CPNE7mitochondrial matrixOne of 3 routes

4,8,12-trimethyltridecanoyl-CoAReach from here →

Catalysed by ALAS1, CPNE7, ACAA1, MYO5Bmitochondrial matrix, peroxisomeOne of 2 routes

(6Z,9Z,12Z)-octadecatrienoyl-CoAReach from here →

Catalysed by ALAS1, CPNE7, SLC27A2, ACSL4 and 6 moremitochondrial matrix, cytosolOne of 7 routes

butanoyl-CoAReach from here →

Catalysed by ALAS1, CPNE7, ACSM4, ACSM1 and 4 moremitochondrial matrix, cytosolOne of 9 routes

dodecanoyl-CoAReach from here →

Catalysed by ALAS1, CPNE7, SLC27A2, ACSL4 and 6 moremitochondrial matrix, cytosolOne of 9 routes

glutaryl-CoAReach from here →

Catalysed by ALAS1, CPNE7, CPT1A, CPT1C and 1 moremitochondrial matrix, cytosolOne of 2 routes

eicosanoyl-CoAReach from here →

Catalysed by ALAS1, CPNE7, SLC27A2, ACSL4 and 6 moremitochondrial matrix, cytosolOne of 12 routes