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Proteins/UNIPROT:O00154
Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels. Preferentially hydrolyzes palmitoyl-CoA, but has a broad specificity acting on other fatty acyl-CoAs with chain-lengths of C8-C18. May play an important physiological function in brain..
Function from UniProtKB (O00154), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
129 statements
129 statements · 7 reference databases · Subject: ACOT7 · Sources: Bgee, Hetionet, Human Protein Atlas, Human-GEM, Reactome, Rhea, WikiPathways
82 reactions
water+propionyl-CoACHEBI:1146900+proton+propionic acid
Catalysed by ACOT7
Reaction pageLeft to rightBalancedEC 3.1.2.2cytosol
Human-GEM MAR00154CC BY 4.0Reference data
water+dodecanoyl-CoACHEBI:1146900+proton+dodecanoate
Catalysed by ACOT1 or
7 names
Resolves to: ACOT7
Reaction pageLeft to rightBalancedEC 3.1.2.2cytosol
Human-GEM MAR00189CC BY 4.0Reference data
water+MAM03050cCHEBI:1146900+proton+MAM03051c
Catalysed by ACOT1 or ACOT7 or BAAT or ACOT13
Reaction pageLeft to rightBalancedEC 3.1.2.2cytosol
Human-GEM MAR00193CC BY 4.0Reference data
water+tetradecanoyl-CoACHEBI:1146900+proton+tetradecanoate
Catalysed by ACOT1 or ACOT7 or BAAT or ACOT13 or THEM4
Reaction pageLeft to rightBalancedEC 3.1.2.2cytosol
Human-GEM MAR00197CC BY 4.0Reference data
MAM00129c+waterMAM00128c+CHEBI:1146900+proton
Catalysed by ACOT1 or ACOT7 or BAAT or ACOT13 or THEM4
Reaction pageLeft to rightBalancedEC 3.1.2.2cytosol
Human-GEM MAR00201CC BY 4.0Reference data
(7Z)-tetradecenoyl-CoA+waterMAM00117c+CHEBI:1146900+proton
Catalysed by ACOT1 or ACOT7 or BAAT or ACOT13 or THEM4
Reaction pageLeft to rightBalancedEC 3.1.2.2cytosol
Human-GEM MAR00206CC BY 4.0Reference data
(5Z)-tetradecenoyl-CoA+waterCHEBI:1146900+proton+MAM02745c
Catalysed by ACOT1 or ACOT7 or BAAT or THEM4
Reaction pageLeft to rightBalancedEC 3.1.2.2cytosol
Human-GEM MAR00210CC BY 4.0Reference data
water+MAM02689cCHEBI:1146900+proton+MAM02690c
Catalysed by ACOT1 or ACOT7 or BAAT or ACOT13 or THEM4
Reaction pageLeft to rightBalancedEC 3.1.2.2cytosol
Human-GEM MAR00214CC BY 4.0Reference data
water+palmitoyl-CoACHEBI:1146900+proton+hexadecanoic acid
Catalysed by ACOT1 or ACOT7 or BAAT or ACOT13 or THEM4
Reaction pageLeft to rightBalancedEC 3.1.2.2cytosol
Human-GEM MAR00223CC BY 4.0Reference data
water+(9Z)-hexadecenoyl-CoACHEBI:1146900+proton+(9Z)-hexadecenoate
Catalysed by ACOT1 or ACOT7 or BAAT or ACOT13 or THEM4
Reaction pageLeft to rightBalancedEC 3.1.2.2cytosol
Human-GEM MAR00230CC BY 4.0Reference data
(7Z)-hexadecenoyl-CoA+waterMAM01197c+CHEBI:1146900+proton
Catalysed by ACOT1 or ACOT7 or BAAT or ACOT13 or THEM4
Reaction pageLeft to rightBalancedEC 3.1.2.2cytosol
Human-GEM MAR00234CC BY 4.0Reference data
water+heptadecanoyl-CoACHEBI:1146900+proton+MAM02456c
Catalysed by ACOT1 or ACOT7 or BAAT or ACOT13 or THEM4
Reaction pageLeft to rightBalancedEC 3.1.2.2cytosol
Human-GEM MAR00238CC BY 4.0Reference data