oxalic acid

Three steps

• a quinolReach from here →
  1. Mitochondrial Carrier (Mc) Tcdb:2.A.29.7.2
  2. Citrate Transport, Mitochondrial
  3. (S)-malate + a quinone = enol-oxaloacetate + a quinol

  Catalysed by SLC25A1, SDHB, SDHAmitochondrial matrix, cytosol

• alpha-linolenic acidReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. Carnitine Transport by Atb0
  3. Utilized Transport

  Catalysed by SLC26A6, SLC6A14extracellular space, cytosol, endoplasmic reticulum

• phenylacetylglycineReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. transport of chloride and glycine (cytosol to extracellular)
  3. phenylacetyl-CoA:glycine N-phenylacetyltransferase

  Catalysed by SLC26A6, SLC6A9, SLC6A14, GLYATextracellular space, cytosolOne of 3 routes

• 5-hydroxytryptophanReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. Transport of L-Tryptophan by Atb0 Transporter
  3. L-Tryptophan, Tetrahydrobiopterin:Oxygen Oxidoreductase (5-Hydroxylating)

  Catalysed by SLC26A6, SLC6A14, TPH1, TPH2extracellular space, cytosolOne of 2 routes

• CHEBI:28666Reach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. transport of chloride and glycine (cytosol to extracellular)
  3. LTD4 hydrolysis

  Catalysed by SLC26A6, SLC6A9, SLC6A14extracellular space, cytosol

• 3beta-hydroxyandrost-5-en-17-oneReach from here →
  1. transport of oxalate and sulfate (cytosol to extracellular)
  2. dehydroepiandrosterone 3-sulfate + H2O = 3beta-hydroxyandrost-5-en-17-one + sulfate + H(+)
  3. 3beta-Hydroxyandrost-5-en-17-one 3-sulfate sulfohydrolase

  Catalysed by SLC26A6, STSextracellular space, cytosolOne of 3 routes

• pyridoxine 5'-phosphateReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. transport of alanine and chloride (cytosol to extracellular)
  3. L-selenocysteine selenide-lyase (L-alanine-forming)

  Catalysed by SLC26A6, SLC6A14, SCLYextracellular space, cytosol

• N-acetyl-L-cysteineReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. transport of chloride and cysteine (cytosol to extracellular)
  3. N-acetylglutamate synthase (N-acetyl-L-cysteine)

  Catalysed by SLC26A6, SLC6A14, NAGSextracellular space, cytosol, mitochondrial matrix

• K(+)Reach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. transport of chloride and cysteine (cytosol to extracellular)
  3. K(+)(in) + L-cysteine(out) + 3 Na(+)(out) + H(+)(out) = K(+)(out) + L-cysteine(in) + 3 Na(+)(in) + H(+)(in)

  Catalysed by SLC26A6, SLC6A14, SLC1A1extracellular space, cytosol, inner side of the membrane, outer side of the membraneOne of 6 routes

• Ca(2+)Reach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. transport of chloride (cytosol to extracellular)
  3. transport of Ca2+ and K+ (cytosol to extracellular)

  Catalysed by SLC26A6, SLC12A2, SLC12A1, SLC24A1 and 4 moreextracellular space, cytosol

• Cys-tRNA(Cys)Reach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. transport of chloride and cysteine (cytosol to extracellular)
  3. L-Cysteine:tRNA(Cys) ligase (AMP-forming)

  Catalysed by SLC26A6, SLC6A14, CARS1extracellular space, cytosol

• Phe-tRNA(Phe)Reach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. Transport of L-Phenylalanine by Atb0 Transporter
  3. L-Phenylalanine:tRNA(Ala) ligase (AMP-forming)

  Catalysed by SLC26A6, SLC6A14, FARSB, FARSAextracellular space, cytosol

• Gly-tRNA(Gly)Reach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. transport of chloride and glycine (cytosol to extracellular)
  3. glycine:tRNA(Gly) ligase (AMP-forming)

  Catalysed by SLC26A6, SLC6A9, SLC6A14, GARS1extracellular space, cytosol

• Asp-tRNA(Asp)Reach from here →
  1. transport of oxalate and sulfate (cytosol to extracellular)
  2. L-aspartate(in) + sulfate(out) = L-aspartate(out) + sulfate(in)
  3. L-Aspartate:tRNA(Asp) ligase (AMP-forming)

  Catalysed by SLC26A6, SLC25A14, SLC25A30, DARS1extracellular space, cytosol, inner side of the membrane, outer side of the membrane

• Trp-tRNA(Trp)Reach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. Transport of L-Tryptophan by Atb0 Transporter
  3. L-Tryptophan -tRNA(Trp) ligase (AMP-forming)

  Catalysed by SLC26A6, SLC6A14, WARS1extracellular space, cytosol

• Ile-tRNA(Ile)Reach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. transport of chloride and isoleucine (cytosol to extracellular)
  3. L-Isoleucine:tRNA(Ile) ligase (AMP-forming)

  Catalysed by SLC26A6, SLC6A14, IARS1extracellular space, cytosol

• Gln-tRNA(Gln)Reach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. Transport of L-Glutamine by Atb0 Transporter
  3. L-Glutamine:tRNA(Gln) ligase (AMP-forming)

  Catalysed by SLC26A6, SLC6A14, QARS1extracellular space, cytosol

• hypoioditeReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. transport of chloride and iodide (cytosol to extracellular)
  3. iodide + H2O2 = hypoiodite + H2O

  Catalysed by SLC26A6, SLC26A4, MPO, LPOextracellular space, cytosol

• Asn-tRNA(Asn)Reach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. Transport of L-Asparagine by Atb0 Transporter
  3. L-Asparagine:tRNA(Asn) ligase (AMP-forming)

  Catalysed by SLC26A6, SLC6A14, NARS1extracellular space, cytosol

• phosphocholineReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. transport of chloride and choline (cytosol to extracellular)
  3. phosphocholine + H2O = choline + phosphate

  Catalysed by SLC26A6, SLC5A7, PHOSPHO1extracellular space, cytosolOne of 2 routes

• glycocholateReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. transport of chloride and glycine (cytosol to extracellular)
  3. bile acid-CoA: amino acid N-acyltransferase

  Catalysed by SLC26A6, SLC6A9, SLC6A14, BAATextracellular space, cytosol, peroxisomeOne of 3 routes

• hydrogen sulfideReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. transport of chloride and cysteine (cytosol to extracellular)
  3. L-cysteine hydrogen-sulfide-lyase (deaminating

  Catalysed by SLC26A6, SLC6A14, CTHextracellular space, cytosolOne of 4 routes

• acetateReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. transport of chloride and formate (cytosol to extracellular)
  3. transport of acetate and formate (cytosol to extracellular)

  Catalysed by SLC26A6, SLC26A4, SLC16A4, SLC16A5 and 1 moreextracellular space, cytosolOne of 2 routes

• CHEBI:30249Reach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. Transport of L-Tryptophan by Atb0 Transporter
  3. L-tryptophan:oxygen 2,3-oxidoreductase (decyclizing)

  Catalysed by SLC26A6, SLC6A14, IDO1, TDO2 and 1 moreextracellular space, cytosol

• propionic acidReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. transport of chloride and formate (cytosol to extracellular)
  3. transport of formate and propanoate (cytosol to extracellular)

  Catalysed by SLC26A6, SLC26A4, SLC16A4, SLC16A5 and 1 moreextracellular space, cytosolOne of 2 routes

• butyric acidReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. transport of chloride and formate (cytosol to extracellular)
  3. transport of butyrate and formate (cytosol to extracellular)

  Catalysed by SLC26A6, SLC26A4, SLC16A4, SLC16A5extracellular space, cytosolOne of 2 routes

• (9Z)-octadecenoateReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. Carnitine Transport by Atb0
  3. Utilized Transport

  Catalysed by SLC26A6, SLC6A14extracellular space, cytosol, endoplasmic reticulumOne of 2 routes

• (indol-3-yl)acetateReach from here →
  1. transport of oxalate and sulfate (cytosol to extracellular)
  2. a dicarboxylate(in) + sulfate(out) = a dicarboxylate(out) + sulfate(in)
  3. (indol-3-yl)acetate(out) + a dicarboxylate(in) = (indol-3-yl)acetate(in) + a dicarboxylate(out)

  Catalysed by SLC26A6, SLC25A35, SLC25A34, SLC22A6 and 1 moreextracellular space, cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

• glutarateReach from here →
  1. Mitochondrial Carrier (Mc) Tcdb:2.A.29.7.2
  2. cis-aconitate carboxy-lyase
  3. itaconate + glutaryl-CoA = itaconyl-CoA + glutarate

  Catalysed by SLC25A1, ACOD1, SUGCTmitochondrial matrix, cytosolOne of 5 routes

• 4-hydroxy-2-oxoglutaric acidReach from here →
  1. Mitochondrial Carrier (Mc) Tcdb:2.A.29.7.2
  2. ATP citrate lyase (citrate)
  3. D-aspartate:2-oxoglutarate aminotransferase

  Catalysed by SLC25A1, ACLY, GOT2mitochondrial matrix, cytosol

• pentanoateReach from here →
  1. transport of oxalate and sulfate (cytosol to extracellular)
  2. dehydroepiandrosterone 3-sulfate + H2O = 3beta-hydroxyandrost-5-en-17-one + sulfate + H(+)
  3. pentanoate(out) + dehydroepiandrosterone 3-sulfate(in) = pentanoate(in) + dehydroepiandrosterone 3-sulfate(out)

  Catalysed by SLC26A6, STS, SLC22A9extracellular space, cytosol, inner side of the membrane, outer side of the membraneOne of 4 routes

• (9Z)-hexadecenoateReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. Carnitine Transport by Atb0
  3. Utilized Transport

  Catalysed by SLC26A6, SLC6A14extracellular space, cytosol, endoplasmic reticulumOne of 6 routes

• (5Z,8Z,11Z,14Z)-eicosatetraenoateReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. Carnitine Transport by Atb0
  3. Utilized Transport

  Catalysed by SLC26A6, SLC6A14extracellular space, cytosol, endoplasmic reticulumOne of 2 routes

• L-lysineReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. transport of arginine and chloride (cytosol to extracellular)
  3. L-lysine(out) + L-arginine(in) = L-lysine(in) + L-arginine(out)

  Catalysed by SLC26A6, SLC6A14, SLC7A9, SLC25A29 and 1 moreextracellular space, cytosol, inner side of the membrane, outer side of the membraneOne of 3 routes

• putrescineReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. transport of arginine and chloride (cytosol to extracellular)
  3. Putrescine Export via Putrescine/Arginine Antiporter

  Catalysed by SLC26A6, SLC6A14, SLC3A2, SLC7A7extracellular space, cytosol

• N-carbamoyl-L-aspartateReach from here →
  1. transport of oxalate and sulfate (cytosol to extracellular)
  2. L-aspartate(in) + sulfate(out) = L-aspartate(out) + sulfate(in)
  3. carbamoyl phosphate + L-aspartate = N-carbamoyl-L-aspartate + phosphate + H(+)

  Catalysed by SLC26A6, SLC25A14, SLC25A30, CADextracellular space, cytosol, inner side of the membrane, outer side of the membrane

• 3-oxopropanoateReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. transport of beta-alanine and chloride (cytosol to extracellular)
  3. 3-oxopropanoate + L-alanine = beta-alanine + pyruvate

  Catalysed by SLC26A6, SLC6A6, SLC6A14, AGXT2extracellular space, cytosol

• 4-methylthio-2-oxobutanoic acidReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. transport of chloride and methionine (cytosol to extracellular)
  3. L-Methionine:oxygen oxidoreductase (deaminating)

  Catalysed by SLC26A6, SLC6A14, IL4I1extracellular space, cytosol

• di-mu-sulfido-diiron(2+)Reach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. transport of chloride and cysteine (cytosol to extracellular)
  3. De novo synthesis of 2Fe2S

  Catalysed by SLC26A6, SLC6A14, NDUFAB1, FDXR and 5 moreextracellular space, cytosol, mitochondrial matrix

• a phenolReach from here →
  1. transport of oxalate and sulfate (cytosol to extracellular)
  2. an aryl sulfate + H2O = a phenol + sulfate + H(+)
  3. an aryl sulfate + H2O = a phenol + sulfate + H(+)

  Catalysed by SLC26A6, ARSL, ARSF, ARSK and 3 moreextracellular space, cytosol

• serotoninReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. transport of chloride (cytosol to extracellular)
  3. transport of serotonin (cytosol to extracellular)

  Catalysed by SLC26A6, SLC12A2, SLC12A1, SLC6A4extracellular space, cytosol

• (S)-3-methyl-2-oxopentanoateReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. transport of chloride and isoleucine (cytosol to extracellular)
  3. L-isoleucine + 2-oxoglutarate = (S)-3-methyl-2-oxopentanoate + L-glutamate

  Catalysed by SLC26A6, SLC6A14, BCAT2, BCAT1extracellular space, cytosol

• D-cysteineReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. transport of alanine and chloride (cytosol to extracellular)
  3. D-cysteine(out) + L-alanine(in) = D-cysteine(in) + L-alanine(out)

  Catalysed by SLC26A6, SLC6A14, SLC7A10extracellular space, cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

• D-serineReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. Transport of L-Glutamine by Atb0 Transporter
  3. D-serine(in) + L-glutamine(out) + Na(+)(out) = D-serine(out) + L-glutamine(in) + Na(+)(in)

  Catalysed by SLC26A6, SLC6A14, SLC1A5extracellular space, cytosol, inner side of the membrane, outer side of the membraneOne of 10 routes

• an acylcholineReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. transport of chloride and choline (cytosol to extracellular)
  3. an acylcholine + H2O = a carboxylate + choline + H(+)

  Catalysed by SLC26A6, SLC5A7, BCHEextracellular space, cytosol

• 5-aminolevulinateReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. transport of chloride and glycine (cytosol to extracellular)
  3. succinyl-CoA + glycine + H(+) = 5-aminolevulinate + CO2 + CoA

  Catalysed by SLC26A6, SLC6A9, SLC6A14, ALAS1 and 1 moreextracellular space, cytosol

• 3-methyl-2-oxovaleric acidReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. transport of chloride and isoleucine (cytosol to extracellular)
  3. L-Leucine:2-oxoglutarate aminotransferase

  Catalysed by SLC26A6, SLC6A14, BCAT1extracellular space, cytosolOne of 2 routes

• 3-(4-hydroxyphenyl)pyruvateReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. Transport of L-Tyrosine by Atb0 Transporter
  3. L-tyrosine:2-oxoglutarate aminotransferase

  Catalysed by SLC26A6, SLC6A14, GOT2, GOT1 and 1 moreextracellular space, cytosolOne of 3 routes

• glycochenodeoxycholateReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. transport of chloride and glycine (cytosol to extracellular)
  3. chenodeoxycholoyl-CoA + glycine = glycochenodeoxycholate + CoA + H(+)

  Catalysed by SLC26A6, SLC6A9, SLC6A14, BAATextracellular space, cytosol

• taurocholateReach from here →
  1. transport of chloride and oxalate (cytosol to extracellular)
  2. Neurotransmitter:Sodium Symporter (Nss) Tcdb:2.A.22.3.3
  3. Choloyl-CoA:glycine N-choloyltransferase

  Catalysed by SLC26A6, SLC6A6, BAATextracellular space, cytosol, peroxisomeOne of 3 routes