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Proteins/UNIPROT:P53396
Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate in multiple biochemical reactions in protein, carbohydrate and lipid metabolism..
Function from UniProtKB (P53396), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
422 statements
422 statements · 9 reference databases · Subject: ACLY · Sources: Bgee, gene ontology, Hetionet, Human Protein Atlas, Human-GEM, Reactome, Rhea, UniProt, WikiPathways · Rows fetched: 300
2 reactions
ATP+citric acid+CHEBI:1146900CHEBI:15351+ADP+oxaloacetate+phosphate(3-)
Catalysed by ACLY
Reaction pageLeft to rightBalancedEC 2.3.3.8cytosol
Human-GEM MAR04149CC BY 4.0Reference data
3 names
Resolves to: ACLY
Catalysed by ACLY
Reaction pageRight to leftBalanced
Rhea RHEA:21160CC BY 4.0Reference data