Compound
4-hydroxy-2-oxoglutaric acid
An oxo dicarboxylic acid comprising glutaric acid having oxo- and hydroxy substituents at the 2- and 4-positions respectively.
Definition from ChEBI (CHEBI:30923), read 2026-09-23. CC BY 4.0.
What it touches on the way
Mechanistic reach
1 entity
1 entities reached.
0 reported hops1 assembled from the scaffold
What the reference databases state
Statements
1 statement
1 statement · 1 reference database · Subject: 4-hydroxy-2-oxoglutaric acid · Sources: Human-GEM
- 4-hydroxy-2-oxoglutaric acid is a substrate of HOGA1ProteinHuman-GEM MAR04787Inferred only
Reactions
6 reactions
2-oxoglutarate(2-)+MAM02358m4-hydroxy-2-oxoglutaric acid+L-glutamate(1-)
Reaction pageLeft to rightBalancedEC 2.6.1.1, 2.6.1.23GO:0005759
Human-GEM MAR04786CC BY 4.0Reference data
4-hydroxy-2-oxoglutaric acidglyoxylic acid+pyruvate
Catalysed by HOGA1
Reaction pageLeft to rightBalancedEC 4.1.3.16GO:0005759
Human-GEM MAR04787CC BY 4.0Reference data
MAM02358m+oxaloacetate4-hydroxy-2-oxoglutaric acid+L-aspartate
Catalysed by GOT2
Reaction pageLeft to rightBalancedEC 2.6.1.21GO:0005759
Human-GEM MAR08098CC BY 4.0Reference data
2-oxoglutarate(2-)+MAM02358c4-hydroxy-2-oxoglutaric acid+L-glutamate(1-)
Catalysed by GOT1
Reaction pageLeft to rightBalancedEC 2.6.1.1GO:0005829
Human-GEM MAR11399CC BY 4.0Reference data
CHEBI:32812+2-oxoglutarate(2-)4-hydroxy-2-oxoglutaric acid+L-glutamate(1-)
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:10480CC BY 4.0Reference data
4-hydroxy-2-oxoglutaric acidglyoxylate+pyruvate
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:18169CC BY 4.0Reference data
Other names
1 name
Resolves to: 4-hydroxy-2-oxoglutaric acid
- Systematic name
- 2-hydroxy-4-oxopentanedioic acid