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Proteins/UNIPROT:P48775
Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety..
Function from UniProtKB (P48775), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
20 statements
20 statements · 7 reference databases · Subject: TDO2 · Sources: Bgee, Hetionet, Human-GEM, Reactome, Rhea, UniProt, WikiPathways
2 reactions
dioxygen+L-tryptophanCHEBI:30249
Catalysed by IDO1 or TDO2 or IDO2
Reaction pageLeft to rightBalancedEC 1.13.11.11, 1.13.11.52cytosol
Human-GEM MAR04214CC BY 4.0Reference data
L-tryptophan+dioxygenN-formyl-L-kynurenine
Catalysed by IDO1 or TDO2 or IDO2
Reaction pageDirection not asserted
7 names
Resolves to: TDO2
Rhea RHEA:24536CC BY 4.0Reference data