serotonin

1. acetyl-CoA:aralkylamine N-acetyltransferase

Catalysed by AANATcytosol

1. transport of serotonin (cytosol to extracellular)

Catalysed by SLCO1A2, SLCO1B3extracellular space, cytosolOne of 2 routes

1. transport of GSH and serotonin (cytosol to extracellular)

Catalysed by SLCO1A2, SLCO1B3extracellular space, cytosolOne of 2 routes

1. acetyl-CoA:aralkylamine N-acetyltransferase

Catalysed by AANATcytosol

1. 5-hydroxy-L-tryptophan + H(+) = serotonin + CO2

Catalysed by DDC

1. serotonin + 3'-phosphoadenylyl sulfate = serotonin O-sulfate + adenosine 3',5'-bisphosphate + H(+)

Catalysed by SULT1A3, SULT1A4

1. transport of serotonin (cytosol to extracellular)

Catalysed by SLC6A4extracellular space, cytosol

1. serotonin(out) + K(+)(in) + Na(+)(out) + H(+)(in) = serotonin(in) + K(+)(out) + Na(+)(in) + H(+)(out)

Catalysed by SLC6A4inner side of the membrane, outer side of the membrane

1. S-Adenosyl-L-methionine:amine N-methyltransferase

Catalysed by INMTcytosol

1. 5-Hydroxytryptamine:oxygen oxidoreductase(deaminating)(flavin-containing)

Catalysed by MAOA, MAOBcytosolOne of 2 routes

1. acetyl-CoA:aralkylamine N-acetyltransferase
2. Carnitine O-Palmitoyltransferase

Catalysed by AANAT, CPT1A, CPT1C, CPT1BcytosolOne of 244 routes

1. transport of serotonin (cytosol to extracellular)
2. transport of S-glutathionyl-2-4-dinitrobenzene (cytosol to extracellular)

Catalysed by SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes