L-lysine

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

353 compounds within 3 steps: 7 in 1, 60 in 2, 286 in 3

One step

epsilon-(gamma-L-glutamyl)-L-lysineReach from here →
1. epsilon-(gamma-L-glutamyl)-L-lysine = 5-oxo-L-proline + L-lysine
Catalysed by GGACT
L-leucineReach from here →
1. L-lysine(in) + L-leucine(out) + Na(+)(out) = L-lysine(out) + L-leucine(in) + Na(+)(in)
Catalysed by SLC7A7inner side of the membrane, outer side of the membraneOne of 2 routes
L-arginineReach from here →
1. L-lysine(out) + L-arginine(in) = L-lysine(in) + L-arginine(out)
Catalysed by SLC7A9, SLC25A29, SLC7A6inner side of the membrane, outer side of the membrane
biocytinReach from here →
1. biocytin + H2O = biotin + L-lysine
Catalysed by BTD
L-ornithineReach from here →
1. L-ornithine(out) + L-lysine(in) = L-ornithine(in) + L-lysine(out)
Catalysed by SLC25A2, SLC25A15inner side of the membrane, outer side of the membraneOne of 2 routes
L-saccharopineReach from here →
1. L-saccharopine + NADP(+) + H2O = L-lysine + 2-oxoglutarate + NADPH + H(+)
Catalysed by AASS
N(omega),N(omega)-dimethyl-L-arginineReach from here →
1. N(omega),N(omega)-dimethyl-L-arginine(in) + L-lysine(out) = N(omega),N(omega)-dimethyl-L-arginine(out) + L-lysine(in)
Catalysed by SLC25A2inner side of the membrane, outer side of the membraneOne of 2 routes

Two steps

CHEBI:1146900Reach from here →
1. L-lysine(in) + L-leucine(out) + Na(+)(out) = L-lysine(out) + L-leucine(in) + Na(+)(in)
2. Acetylation of Leucine
Catalysed by SLC7A7inner side of the membrane, outer side of the membrane, mitochondrial matrix
N(omega)-methyl-L-arginineReach from here →
1. L-lysine(out) + L-arginine(in) = L-lysine(in) + L-arginine(out)
2. N(omega)-methyl-L-arginine(in) + L-arginine(out) = N(omega)-methyl-L-arginine(out) + L-arginine(in)
Catalysed by SLC7A9, SLC25A29, SLC7A6inner side of the membrane, outer side of the membraneOne of 2 routes
N-(9Z-octadecenoyl)-L-leucine

Reach from here →

Catalysed by SLC7A7, PM20D1inner side of the membrane, outer side of the membrane

D-histidineReach from here →

Catalysed by SLC25A2, SLC25A15inner side of the membrane, outer side of the membraneOne of 2 routes

L-homoarginineReach from here →

Catalysed by SLC25A2, SLC25A15inner side of the membrane, outer side of the membraneOne of 4 routes

kinetensinReach from here →

Catalysed by SLC7A7, CMA1inner side of the membrane, outer side of the membrane, extracellular spaceOne of 2 routes

CHEBI:15699Reach from here →

Catalysed by SLC25A2, SLC25A15, SLC7A6inner side of the membrane, outer side of the membrane, extracellular space, cytosolOne of 7 routes

CHEBI:15765Reach from here →

Catalysed by SLC7A7, SLC3A2, SLC7A5inner side of the membrane, outer side of the membrane, extracellular space, cytosol

CHEBI:15971Reach from here →

Catalysed by SLC25A2, SLC25A15, SLC7A5, SLC7A6inner side of the membrane, outer side of the membrane, extracellular space, cytosolOne of 12 routes

ureaReach from here →

Catalysed by SLC7A9, SLC25A29, SLC7A6, ARG1inner side of the membrane, outer side of the membrane, cytosolOne of 3 routes

L-cystineReach from here →

Catalysed by SLC7A9, SLC25A29, SLC7A6inner side of the membrane, outer side of the membraneOne of 2 routes

L-citrullineReach from here →

Catalysed by SLC25A2, SLC25A15, SLC7A9inner side of the membrane, outer side of the membrane, extracellular space, cytosolOne of 20 routes

L-valineReach from here →

Catalysed by SLC25A2, SLC25A15, SLC7A6inner side of the membrane, outer side of the membrane, extracellular space, cytosolOne of 8 routes

nitric oxideReach from here →

Catalysed by SLC7A9, SLC25A29, SLC7A6, NOS3 and 2 moreinner side of the membrane, outer side of the membrane, cytosolOne of 2 routes

protein polypeptide chainReach from here →

Catalysed by SLC7A9, SLC25A29, SLC7A6inner side of the membrane, outer side of the membrane, cytosolOne of 2 routes

N(2)-acetyl-L-ornithineReach from here →

Catalysed by SLC25A2, SLC25A15, ACY1inner side of the membrane, outer side of the membrane, cytosol

CHEBI:16857Reach from here →

Catalysed by SLC25A2, SLC25A15, SLC7A6inner side of the membrane, outer side of the membrane, extracellular space, cytosolOne of 8 routes

L-isoleucineReach from here →

Catalysed by SLC25A2, SLC25A15, SLC7A6inner side of the membrane, outer side of the membrane, extracellular space, cytosolOne of 7 routes

CHEBI:17203Reach from here →

Catalysed by SLC25A2, SLC25A15, SLC7A6inner side of the membrane, outer side of the membrane, extracellular space, cytosolOne of 7 routes

L-glutamic 5-semialdehydeReach from here →

Catalysed by SLC25A2, SLC25A15, OATinner side of the membrane, outer side of the membrane, mitochondrial matrix

agmatineReach from here →

Catalysed by SLC7A9, SLC25A29, SLC7A6inner side of the membrane, outer side of the membrane, mitochondrial matrix

L-cysteineReach from here →

Catalysed by SLC25A2, SLC25A15, SLC7A6inner side of the membrane, outer side of the membrane, extracellular space, cytosolOne of 10 routes

4-methyl-2-oxopentanoateReach from here →

Catalysed by SLC7A7, BCAT2inner side of the membrane, outer side of the membrane, mitochondrial matrixOne of 4 routes

CHEBI:17895Reach from here →

Catalysed by SLC25A2, SLC25A15, SLC7A6inner side of the membrane, outer side of the membrane, extracellular space, cytosolOne of 8 routes

CHEBI:17927Reach from here →

Catalysed by SLC7A9, SLC25A29, SLC7A6, SLC3A2inner side of the membrane, outer side of the membrane, extracellular space, cytosol

CHEBI:18019Reach from here →

Catalysed by GGACTcytosolOne of 16 routes

L-glutamineReach from here →

Catalysed by SLC25A2, SLC25A15, SLC7A6inner side of the membrane, outer side of the membrane, extracellular space, cytosolOne of 11 routes

CHEBI:18183Reach from here →

Catalysed by GGACTcytosolOne of 2 routes

S-methylmercury-L-cysteineReach from here →

Catalysed by SLC7A7, SLC7A8inner side of the membrane, outer side of the membraneOne of 2 routes

5-(3,3-dimethylguanidino)-2-oxopentanoateReach from here →

Catalysed by SLC25A2, AGXT2inner side of the membrane, outer side of the membraneOne of 6 routes

chlorine(.)Reach from here →

Catalysed by SLC7A9, SLC25A29, SLC7A6, SLC6A14inner side of the membrane, outer side of the membrane, extracellular space, cytosolOne of 4 routes

L-aspartateReach from here →

Catalysed by SLC25A2, AGXT2inner side of the membrane, outer side of the membraneOne of 3 routes

D-lysineReach from here →

Catalysed by SLC25A2, SLC25A15inner side of the membrane, outer side of the membraneOne of 2 routes

putrescineReach from here →

Catalysed by SLC25A2, SLC25A15, ODC1inner side of the membrane, outer side of the membrane, cytosolOne of 4 routes

D-arginineReach from here →

Catalysed by SLC25A2, SLC25A15inner side of the membrane, outer side of the membraneOne of 2 routes

glycineReach from here →

Catalysed by SLC25A2, SLC25A15, GATMinner side of the membrane, outer side of the membrane, cytosolOne of 12 routes

2-(N(omega)-L-arginino)succinateReach from here →

Catalysed by SLC7A9, SLC25A29, SLC7A6, ASLinner side of the membrane, outer side of the membrane, cytosolOne of 2 routes

4-guanidinobutanoateReach from here →

Catalysed by SLC7A9, SLC25A29, SLC7A6, GATMinner side of the membrane, outer side of the membrane

biotinReach from here →

Catalysed by BTDmitochondrial matrixOne of 5 routes

3-guanidinopropanoateReach from here →

Catalysed by SLC7A9, SLC25A29, SLC7A6, GATMinner side of the membrane, outer side of the membrane

L-histidineReach from here →

Catalysed by SLC25A2, SLC25A15inner side of the membrane, outer side of the membraneOne of 5 routes

D-ornithineReach from here →

Catalysed by SLC25A2, SLC25A15inner side of the membrane, outer side of the membraneOne of 2 routes

guanidinoacetateReach from here →

Catalysed by SLC7A9, SLC25A29, SLC7A6, GATMinner side of the membrane, outer side of the membrane, cytosolOne of 2 routes