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Proteins/UNIPROT:Q8N159
Plays a role in the regulation of ureagenesis by producing the essential cofactor N-acetylglutamate (NAG), thus modulating carbamoylphosphate synthase I (CPS1) activity..
Function from UniProtKB (Q8N159), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 2 · substrate of
2 compounds
2 compounds.
0 reported routes2 assembled routes
1 row
27 statements
27 statements · 6 reference databases · Subject: NAGS · Sources: Bgee, Hetionet, Human-GEM, Reactome, Rhea, WikiPathways
6 reactions
CHEBI:1146900+proton+MAM02533mCHEBI:15351+L,L-cystathionine
Catalysed by NAGS
Reaction pageReversibleBalancedEC 2.3.1.1mitochondrial matrix
Human-GEM MAR03922CC BY 4.0Reference data
CHEBI:1146900+proton+MAM02540mCHEBI:15351+L-methionine
Catalysed by NAGS
1 name
Resolves to: NAGS
Human-GEM MAR05418CC BY 4.0Reference data
CHEBI:1146900+proton+N-acetyl-L-cysteineCHEBI:15351+L-cysteine
Catalysed by NAGS
Reaction pageReversibleBalancedEC 2.3.1.1mitochondrial matrix
Human-GEM MAR05419CC BY 4.0Reference data
CHEBI:1146900+proton+MAM02531mCHEBI:15351+L-asparagine
Catalysed by NAGS
Reaction pageReversibleBalancedEC 2.3.1.1mitochondrial matrix
Human-GEM MAR06968CC BY 4.0Reference data
CHEBI:15351+L-glutamate(1-)CHEBI:1146900+proton+MAM02536m
Catalysed by NAGS
Reaction pageLeft to rightBalancedEC 2.3.1.1mitochondrial matrix
Human-GEM MAR08416CC BY 4.0Reference data
L-glutamate(1-)+acetyl-CoAN-acetyl-L-glutamate+coenzyme A(4-)+hydron
Catalysed by NAGS
Reaction pageDirection not assertedBalanced
Rhea RHEA:24292CC BY 4.0Reference data