What it touches on the way
Mechanistic reach
8 entities
8 entities reached.
0 reported hops8 assembled from the scaffold
- HSPA9ProteinUNIPROT:P38646substrate ofInferred only67 paths67 endpoints
- FDXRProteinUNIPROT:P22570substrate ofInferred only18 paths18 endpoints
- FDX2ProteinUNIPROT:Q6P4F2substrate ofInferred only15 paths15 endpoints
- HSCBProteinUNIPROT:Q8IWL3substrate ofInferred only10 paths10 endpoints
- ISCA2ProteinUNIPROT:Q86U28substrate ofInferred only5 paths5 endpoints
- ISCA1ProteinUNIPROT:Q9BUE6substrate ofInferred only5 paths5 endpoints
- GLRX5ProteinUNIPROT:Q86SX6substrate ofInferred only4 paths4 endpoints
- IBA57ProteinUNIPROT:Q5T440substrate ofInferred only1 path1 endpoint
What the reference databases state
Statements
9 statements
9 statements · 1 reference database · Subject: di-mu-sulfido-diiron(2+) · Sources: Human-GEM
- di-mu-sulfido-diiron(2+) is converted to tetra-mu3-sulfido-tetrairon(2+)CompoundHuman-GEM MAR20184Inferred only
- di-mu-sulfido-diiron(2+) is a substrate of FDX2ProteinHuman-GEM MAR20184Inferred only
- di-mu-sulfido-diiron(2+) is a substrate of FDXRProteinHuman-GEM MAR20184Inferred only
- di-mu-sulfido-diiron(2+) is a substrate of GLRX5ProteinHuman-GEM MAR20184Inferred only
- di-mu-sulfido-diiron(2+) is a substrate of HSCBProteinHuman-GEM MAR20184Inferred only
- di-mu-sulfido-diiron(2+) is a substrate of HSPA9ProteinHuman-GEM MAR20184Inferred only
- di-mu-sulfido-diiron(2+) is a substrate of IBA57ProteinHuman-GEM MAR20184Inferred only
- di-mu-sulfido-diiron(2+) is a substrate of ISCA1ProteinHuman-GEM MAR20184Inferred only
- di-mu-sulfido-diiron(2+) is a substrate of ISCA2ProteinHuman-GEM MAR20184Inferred only
Reactions
2 reactions
2ATP+2water+NADPH(4-)+2di-mu-sulfido-diiron(2+)2ADP+3proton+NADP(3-)+2phosphate(3-)+tetra-mu3-sulfido-tetrairon(2+)
Catalysed by FDXR & HSPA9 & IBA57 & FDX2 & GLRX5 & ISCA2 & HSCB & ISCA1
Reaction pageLeft to rightBalancedmitochondrial matrix
Human-GEM MAR20184CC BY 4.0Reference data
2L-cysteine+2iron(2+)+NADPH(4-)2L-alanine+proton+NADP(3-)+di-mu-sulfido-diiron(2+)
Catalysed by NDUFAB1 & FDXR & FXN & FDX2 & ISCU & LYRM4 & NFS1
Reaction pageLeft to rightBalancedmitochondrial matrix
Human-GEM MAR20185CC BY 4.0Reference data
Other names
9 names
Resolves to: di-mu-sulfido-diiron(2+)
- Also called
- [2Fe-2S](2+)[2Fe-2S]2+[Fe2(mu-S)2](2+)[Fe2(μ-S)2]2+[Fe2S2](2+)[Fe2S2]2+
- Systematic name
- di-mu-sulfido-diiron(III)di-μ-sulfido-diiron(2+)di-μ-sulfido-diiron(III)